Clinical characteristics of patients with cardiac arrest induced by pesticide poisoning: Analysis of 15 cases

Jiang, Min; Han, Ling; He, Fei

doi:10.1016/j.medcli.2022.08.006

Cited by 4 publications

(1 citation statement)

References 16 publications

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“…Cardiac arrest, a fatal and an uncommon event caused by acute myocardial infarction [ 1 , 2 ], pesticide poisoning, [ 3 ] trauma, [ 4 ] etc., has an estimated average global incidence of approximately 100 cardiac arrests per 100,000 persons among adults [ 5 , 6 ]. The rate of survival to discharge is 10% in patients with out-of-hospital cardiac arrest worldwide, and 22% in patients with in-hospital cardiac arrest [ 7 – 9 ].…”

Section: Introductionmentioning

confidence: 99%

Serum neurofilament light chain as a predictive marker of neurologic outcome after cardiac arrest: a meta-analysis

Wang

Feng

et al. 2023

BMC Cardiovasc Disord

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Objective Recently, an increasing number of studies have suggested using serum neurofilament light (NfL) chain to predict the neurologic outcome after cardiac arrest. However, the predictive ability of this approach remains inconclusive. Meta-analysis was performed on related studies to assess the ability of serum NfL to predict the neurologic outcome after cardiac arrest. Materials and methods PubMed, ScienceDirect and Embase were systematically searched from the date of their inception until June 2022. Data were extracted to calculate the area under the receiver operating characteristic curve (AUC), the sensitivity, the specificity and the publication bias to evaluate the predictive power of serum NfL using Stata 14.0. Results Nine studies were included in the present meta-analysis. Seven studies involving 1296 participants reported serum NfL 24 h post arrest for predicting the neurological outcome, and the AUC was 0.92 (77% sensitivity and 96% specificity). Seven studies involving 1020 participants reported serum NfL 48 h post arrest for predicting the neurological outcome, and the AUC was 0.94 (78% sensitivity and 98% specificity). Four studies involving 804 participants reported serum NfL 72 h post arrest for predicting the neurological outcome, and the AUC was 0.96 (90% sensitivity and 98% specificity). No significant publication bias was observed among the included studies. Conclusion The present meta-analysis results support the potential use of serum NfL as an early biomarker of neurologic outcome, especially 72 h post arrest.

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