Clinical characteristics of seizures associated with viral gastroenteritis in children

Ueda, Hiroyuki; Tajiri, Hitoshi; Kimura, Shigeharu; Etani, Yuri; Hosoi, Gaku; Maruyama, Tomoko; Noma, Haruyoshi; Kusumoto, Yoshio; Takano, Tomoko; Baba, Yoshiko; Nagai, Toshikazu

doi:10.1016/j.eplepsyres.2014.10.021

Cited by 35 publications

(41 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…We did not find evidence of brain inflammation via CSF studies, although tests were performed in only four of the 12 PSE patients. In previous studies, patients with seizures associated with gastroenteritis showed normal MRI and EEG findings [3][4][5][6][7][8]17,[20][21][22]26,27) , which is consistent with our study findings. Previous studies had few reports on prolonged seizure in CwG 20,22,23,28) without considering the risk factors for prolonged seizure.…”

Section: The Duration Of Seizures In Cwg Is Usually 30 Seconds To <5supporting

confidence: 93%

“…It may result in severe complications such as severe dehydration, bowel obstructions, and convulsions. The relationship between mild viral gastroenteritis and afebrile convulsions has been studied [2][3][4][5][6][7][8] since Morroka initially described convulsions associated with mild viral gastroenteritis in 1982 1) . Convulsions with mild gastroenteritis (CwG) is characterized by an 234 Kang SY, et al • Convulsions with Noroviral Gastroenteritis in Children at a Single Center in Korea http://www.cns.or.kr afebrile (<38℃) condition, and brief, generalized seizures accompanying gastroenteritis without electrolyte abnormalities or dehydration in previously healthy children with normal laboratory values, cerebrospinal fluid values, neuroimaging results, and electroencephalography (EEG) findings.…”

Section: Introductionmentioning

confidence: 99%

“…Rotavirus was the most commonly detected pathogen in CwG [3][4][5] . However, after the introduction of a rotavirus vaccine, norovirus has become the most common cause of viral gastroenteritis [13][14][15][16] , even in cases of CwG in infants and children,…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Convulsions with Noroviral Gastroenteritis in Children at a Single Center in Korea

강수연¹,

이현주²,

김신혜³

2018

Child Neurol

View full text Add to dashboard Cite

Viral gastroenteritis is a common disease in infants and children. Seizures can be associated with viral gastroenteritis as benign convulsions with mild gastroenteritis (CwG). After the development of the rotavirus vaccination, norovirus has become inreasingly significant in children. We retrospectively analyzed the clinical features in a pediatric population presenting with seizures and confirmed enteral viral infections, especially norovirus infections. Methods: We retrospectively reviewed the medical records of pediatric patients aged <15 years admitted due to convulsions and gastroenteritis to the Department of Pediatrics of Myongji Hospital between July 2014 and June 2016. Results: A total of 46 patients (24 male and 22 female) were included. Norovirus was detected in 21 (45.7%) patients, adenovirus in three (6.5%), rotavirus in two (4.3%), astrovirus in one (2.2%), and none of agents were detected in 19 (41.3%) patients. Patients in the norovirus gastroenteritis (NGE) group had a higher incidence of diarrhea than that among in the non-norovirus gastroenteritis (NNGE) group (61.9% vs 28.0%; P<0.05). Twelve patients experienced status epilepticus, including five (23.8%) in the NGE group and seven (33.0%) in the NNGE group (P=0.837). Seizures were effectively terminated by intravenous benzodiazepines in 8 (66.7%) of 12 patients. Additional long-acting antiepileptic drugs such as fosphenytoin or levetiracetam were required in three (25%) of 12 patients. Conclusion: Patients with CwG with and without noroviurs infection did not differ in terms of clinical features. However, status epilepticus was not uncommon among patients with CwG by definition.

show abstract

Section: The Duration Of Seizures In Cwg Is Usually 30 Seconds To <5supporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Convulsions with Noroviral Gastroenteritis in Children at a Single Center in Korea

강수연¹,

이현주²,

김신혜³

2018

Child Neurol

View full text Add to dashboard Cite

show abstract

“…In contrast, a different theory was put forth by Ueda et al in a recent study. 52 They performed a retrospective analysis of 293 consecutive paediatric patients with viral AGE, among whom 18 developed seizures; 8 of the cases did not develop a fever and 10 developed a fever. Almost all of the children with fever presented with seizures at an early stage of AGE and had more episodes of clustered seizures.…”

Section: Factorsmentioning

confidence: 99%

Benign convulsions in children with mild gastroenteritis

Castellazzi

Principi

Agostoni

et al. 2016

European Journal of Paediatric Neurology

View full text Add to dashboard Cite

“…Hence, we presume relevant miss-codification from the MBDS when it is used as data source of risk factors for rotavirus. Because of its neurotropism, rotavirus is the most important agent in benign seizures caused by an AGE [27,28], with seizures occurring in 3% of ARGE cases with no pre-existing neurological conditions [29]. In CLM, seizures were coded less often and only 1·3% of ARGE cases with seizures were complicated with dehydration.…”

Section: Discussionmentioning

confidence: 99%

A multifactorial regression analysis of the features of community-acquired rotavirus requiring hospitalization in Spain as represented in the Minimum Basic Data Set

González

Tenias²

2016

Epidemiol. Infect.

View full text Add to dashboard Cite

Over 10% of acute rotavirus gastroenteritis (ARGE) requires hospitalization because of complications. The aggravating factors have been widely analysed, but in an isolated way. We aimed to explore the interrelationship between the clinical and epidemiological factors that characterize rotavirus hospitalizations in Spain using information from the Minimum Basic Data Set (MBDS). Using ICD-9-CM codes, we classified acute gastroenteritis (AGE) cases by principal diagnosis fields and then categorized their comorbidities, complications, and epidemiological features by secondary fields. A multivariable, logistic, step-wise regression model was then constructed. We identified 1657 ARGE cases from 17 415 cases of AGE. Rotavirus hospitalizations were associated with place of residence, age, and season (P < 0·0001), as well as with dehydration [odds ratio (OR) 12·44, 95% confidence interval (CI) 1·52-40·38], intravenous rehydration (OR 1·74, 95% CI 1·29-2·35), metabolic acidosis (OR 1·51, 95% CI 1·24-1·83), respiratory tract infections (RTIs) (OR 1·60, 95% CI 1·09-1·98), and concomitant AGE (OR 1·52, 95% CI 1·03-2·25). Dehydration was four times more likely in patients aged <5 years (OR 4·36, 95% CI 1·20-12·96) and was associated with acidosis when ARGE and RTI were present simultaneously (P < 0·0001). Specific co-infecting viruses may play a role in acute respiratory symptoms and aggravation of gastrointestinal manifestations of rotaviruses, thus leading to complications requiring hospitalization.

show abstract

Clinical characteristics of seizures associated with viral gastroenteritis in children

Cited by 35 publications

References 24 publications

Convulsions with Noroviral Gastroenteritis in Children at a Single Center in Korea

Convulsions with Noroviral Gastroenteritis in Children at a Single Center in Korea

Benign convulsions in children with mild gastroenteritis

A multifactorial regression analysis of the features of community-acquired rotavirus requiring hospitalization in Spain as represented in the Minimum Basic Data Set

Contact Info

Product

Resources

About