Clinical Characteristics of Six Cases of Tracheobronchopathia Osteochondroplastica

Guo, Rong R; Zhou, Mingming; Wei, Xiaohui; Niu, Ling

doi:10.1155/2020/8685126

Cited by 8 publications

(11 citation statements)

References 16 publications

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“…Some reports have found that the most frequent presentation is chronic cough and dyspnea, 9 which were complaints voiced by our subjects. Some patients also have restrictive or pulmonary ventilation dysfunction 10 ; our patients had slightly anormal pulmonary function.…”

Section: Discussionmentioning

confidence: 57%

Multi-Nodule of Large Airway: Tracheobronchopathia Osteochondroplastica, Two Cases Report and Literature Review

Jiang¹,

Yang²,

Guo

2021

Ear Nose Throat J

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We report two subjects with tracheobronchopathia osteochondroplastica (TO), including the clinical manifestations, histological findings, and clinical treatments, which were analyzed retrospectively. One patient with TO was a 60-year-old woman, and the other was a 47-year-old man. The main clinical manifestations were cough, chest pain, and dyspnea. Computed tomography (CT) images showed that TO mainly occurred in the trachea and main bronchus. Histological analysis showed inflammatory exudation, squamous metaplasia, submucosal cartilaginous, and ossification. We present the two cases to increase physician and patient awareness of this benign disease and to improve their understanding of the disease manifestations and potential complications.

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Section: Discussionmentioning

confidence: 57%

Multi-Nodule of Large Airway: Tracheobronchopathia Osteochondroplastica, Two Cases Report and Literature Review

Jiang¹,

Yang²,

Guo

2021

Ear Nose Throat J

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“… 3 Although TO is rare, there have been many reports in which it was occasionally diagnosed. 1 , 4 – 27 To date, only a limited number of studies have utilized extensive data to conduct a comprehensive investigation of this disease. 3 , 28 …”

Section: Introductionmentioning

confidence: 99%

Building and validating an artificial intelligence model to identify tracheobronchopathia osteochondroplastica by using bronchoscopic images

Chen,

Tang,

Herth

et al. 2024

Ther Adv Respir Dis

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Background: Given the rarity of tracheobronchopathia osteochondroplastica (TO), many young doctors in primary hospitals are unable to identify TO based on bronchoscopy findings. Objectives: To build an artificial intelligence (AI) model for differentiating TO from other multinodular airway diseases by using bronchoscopic images. Design: We designed the study by comparing the imaging data of patients undergoing bronchoscopy from January 2010 to October 2022 by using EfficientNet. Bronchoscopic images of 21 patients with TO at Anhui Chest Hospital from October 2019 to October 2022 were collected for external validation. Methods: Bronchoscopic images of patients with multinodular airway lesions (including TO, amyloidosis, tumors, and inflammation) and without airway lesions in the First Affiliated Hospital of Guangzhou Medical University were collected. The images were randomized (4:1) into training and validation groups based on different diseases and utilized for deep learning by convolutional neural networks (CNNs). Results: We enrolled 201 patients with multinodular airway disease (38, 15, 75, and 73 patients with TO, amyloidosis, tumors, and inflammation, respectively) and 213 without any airway lesions. To find multinodular lesion images for deep learning, we utilized 2183 bronchoscopic images of multinodular lesions (including TO, amyloidosis, tumor, and inflammation) and compared them with images without any airway lesions (1733). The accuracy of multinodular lesion identification was 98.9%. Further, the accuracy of TO detection based on the bronchoscopic images of multinodular lesions was 89.2%. Regarding external validation (using images from 21 patients with TO), all patients could be diagnosed with TO; the accuracy was 89.8%. Conclusion: We built an AI model that could differentiate TO from other multinodular airway diseases (mainly amyloidosis, tumors, and inflammation) by using bronchoscopic images. The model could help young physicians identify this rare airway disease.

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“…La traqueobroncopatía osteocondroplástica es una rara enfermedad, crónica benigna, caracterizada por múltiples nódulos cartilaginosos u óseos submucosos, que se proyectan en la luz de los dos tercios inferiores de la tráquea y la parte superior de los bronquios principales [1]. En algunos casos, la laringe y la tráquea subglótica también pueden estar comprometidas [2,3], causando diversos síntomas respiratorios.…”

Section: Introductionunclassified

Osteochondroplastic tracheobronchopathy: Four case reports

Rodríguez Hidalgo,

Cribillero Meza,

Ruíz Caballero

et al. 2024

Medwave

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Introduction Osteochondroplastic tracheobronchopathy is a rare benign chronic disease of unknown etiology. Bronchoscopy remains the gold standard for diagnosing osteochondroplastic tracheobronchopathy. Its typical findings are described as a cobblestone, rock garden, mountainscape, or stalactite cave appearance. The present work aims to show the main clinical features of this rare pathology. Clinical cases The clinical data of four middle-aged patients, three men and one woman, were analyzed. The main clinical symptoms were chronic cough, dyspnea, and dysphonia. The patient's preliminary diagnosis was made by computed axial tomography of the chest, confirmed by bronchoscopy and histopathological examination. Treatment included medication for symptoms and, in one case, cryosurgery and argon plasma coagulation. Discussion Diagnosing osteochondroplastic tracheobronchopathy was not easy, given its uncommon nature and non-specific symptoms often found in other pathologies. No case series articles on this pathology have been published in Peru. Therefore, we used the original articles published in other countries to reference our findings. Conclusion Osteochondroplastic tracheopathy is a benign disease that typically affects adults. Men are more likely to be affected. Its clinical manifestations are non-specific and frequently of pharyngeal origin, and the cause is not yet defined. Chest computed axial tomography combined with bronchoscopy are the main diagnostic procedures. There is no standard treatment with consistent therapeutic effects.

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Clinical Characteristics of Six Cases of Tracheobronchopathia Osteochondroplastica

Cited by 8 publications

References 16 publications

Multi-Nodule of Large Airway: Tracheobronchopathia Osteochondroplastica, Two Cases Report and Literature Review

Multi-Nodule of Large Airway: Tracheobronchopathia Osteochondroplastica, Two Cases Report and Literature Review

Building and validating an artificial intelligence model to identify tracheobronchopathia osteochondroplastica by using bronchoscopic images

Osteochondroplastic tracheobronchopathy: Four case reports

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