Clinical characteristics, predictors of symptomatic coronavirus disease 2019 and duration of hospitalisation in a cohort of 632 Patients in Lagos State, Nigeria

Erinoso, Olufemi; Wright, Kikelomo Ololade; Anya, Samuel; Bowale, Abimbola; Adejumo, Olusola Adedeji; Adesola, Sunday; Osikomaiya, Bodunrin; Mutiu, Bamidele; Saka, Babatunde; Falana, Ayodeji; Ola-Ayinde, Disu; Akase, Ephraim I; Owuna, Henry; Abdur-Razzaq, Hussein; Lajide, Dayo; Ezechi, Oliver; Ogboye, Olusegun; Osibogun, Akin; Abayomi, Akin

doi:10.4103/npmj.npmj_272_20

Cited by 17 publications

(15 citation statements)

References 4 publications

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“…Whilst earlier studies from Hong Kong and South Korea reported lower rates of asymptomatic cases in treatment centres, asymptomatic cases reported from South-West Nigeria were up to 60%. 7 , 25 , 26 However, patients’ mean age and proportion of patients with comorbidities in our study were similar to those reported from Lagos State. 7 …”

Section: Discussionsupporting

confidence: 86%

“…7,25,26 However, patients' mean age and proportion of patients with comorbidities in our study were similar to those reported from Lagos State. 7 Cough, fever and fatigue were the most predominant symptoms reported in this study, similar to findings from Zhejiang province in China. 27 Our finding of significant association between higher levels of education and presentation of symptoms in patients may account for some differences in the reporting of symptoms.…”

Section: Discussionsupporting

confidence: 86%

“…In our study, nearly half of the patients studied were overweight or obese. However, this was not found to be significantly In addition, despite hypertension and diabetes mellitus being the most frequently observed comorbidities, similar to reports from Lagos State and China, 7,38 comorbidity and age were not found to have significant association with duration of hospitalisation. This is contrary to findings reported from Lagos State and China, which cited older patients as having significantly higher odds of being hospitalised for longer durations.…”

Section: Discussionsupporting

confidence: 70%

“…In this study, comorbidity was not significantly associated with symptomatic presentation following logistic regression, at variance with findings reported from Lagos, South-West Nigeria. 7 The median duration of hospitalisation in this study was about 14 days, less than that reported by the NCDC, where the median length of stay of 111 patients was 19 days. 21 However, both durations are within the range reported from studies outside of China (4-21 days), although lower in range compared with findings documented from China (4-53 days).…”

Section: Discussioncontrasting

confidence: 59%

“…6 Several studies documenting the spectrum of clinical characteristics of COVID-19 patients in South-West Nigeria are available. 6,7,8 However, evidence from Northern Nigeria is not readily available. As the COVID-19 pandemic continues to spread rapidly, with countries recording new waves of heightened infections, it is pertinent that locally derived evidence adds to the body of knowledge and is used to strengthen national and global public health responses to the pandemic.…”

Section: Introductionmentioning

confidence: 99%

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Clinical presentation and hospitalisation duration of 201 coronavirus disease 2019 patients in Abuja, Nigeria

Akerele¹,

Oreh

Kawu³

et al. 2021

African Journal of Primary Health Care & Family Medicine

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Background: Knowledge of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is unfolding. Insights from patient features in different environments are therefore vital to understanding the disease and improving outcomes.Aim: This study aimed to describe patient characteristics associated with symptomatic presentation and duration of hospitalisation in coronavirus disease 2019 (COVID-19) patients managed in Abuja.Setting: The study was conducted in Abuja, the Federal Capital Territory, Nigeria.Methods: This was a retrospective study of 201 COVID-19 patients hospitalised in the Asokoro District Hospital COVID-19 Isolation and Treatment Centre between April 2020 and July 2020. Demographic and clinical data were obtained and outcomes assessed were symptom presentation and duration of hospitalisation.Results: Patients’ median age was 39.3 years (interquartile range [IQR]: 26–52); 65.7% were male and 33.8% were health workers. Up to 49.2% of the patients were overweight or obese, 68.2% had mild COVID-19 at presentation and the most common symptoms were cough (38.3%) and fever (33.8%). Hypertension (22.9%) and diabetes mellitus (7.5%) were the most common comorbidities. The median duration of hospitalisation was 14.4 days (IQR: 9.5–19). Individuals with secondary and tertiary education had higher percentage symptoms presentation (8.5% and 34%, respectively), whilst a history of daily alcohol intake increased the length of hospital stay by 129.0%.Conclusion: Higher educational levels were linked with symptom presentation in COVID-19 patients and that daily alcohol intake was significantly associated with longer hospital stay. These findings highlight the importance of public education on COVID-19 for symptom recognition, early presentation and improved outcomes.

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Section: Discussionsupporting

confidence: 86%

Section: Discussionsupporting

confidence: 86%

Section: Discussionsupporting

confidence: 70%

Section: Discussioncontrasting

confidence: 59%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Clinical presentation and hospitalisation duration of 201 coronavirus disease 2019 patients in Abuja, Nigeria

Akerele¹,

Oreh

Kawu³

et al. 2021

African Journal of Primary Health Care & Family Medicine

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Neurological complications and effects of COVID-19: Symptoms and conceivable mechanisms

Sarıoğlu¹,

Sarıaltın²,

Çoban³

2023

Brain Hemorrhages

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Neurological Manifestations in COVID-19 Patients: A Meta-Analysis

Vitalakumar

Sharma

Kumar

et al. 2021

ACS Chem. Neurosci.

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Common symptoms such as dizziness, headache, olfactory dysfunction, nausea, vomiting, etc. in COVID-19 patients have indicated the involvement of the nervous system. However, the exact association of the nervous system with COVID-19 infection is still unclear. Thus, we have conducted a meta-analysis of clinical studies associated with neurological problems in COVID-19 patients. We have searched for electronic databases with MeSH terms, and the studies for analysis were selected based on inclusion and exclusion criteria and quality assessment. The Stats Direct (version 3) was used for the analysis. The pooled prevalence with 95% confidence interval of various neurological manifestations reported in the COVID-19 patients was found to be headache 14.6% (12.2–17.2), fatigue 33.6% (29.5–37.8), olfactory dysfunction 26.4% (21.8–31.3), gustatory dysfunction 27.2% (22.3–32.3), vomiting 6.7% (5.5–8.0), nausea 9.8% (8.1–11.7), dizziness 6.7% (4.7–9.1), myalgia 21.4% (18.8–24.1), seizure 4.05% (2.5–5.8), cerebrovascular diseases 9.9% (6.8–13.4), sleep disorders 14.9% (1.9–36.8), altered mental status 17.1% (12.3–22.5), neuralgia 2.4% (0.8–4.7), arthralgia 19.9% (15.3–25.0), encephalopathy 23.5% (14.3–34.1), encephalitis 0.6% (0.2–1.3), malaise 38.3% (24.7–52.9), confusion 14.2% (6.9–23.5), movement disorders 5.2% (1.7–10.4), and Guillain–Barre syndrome 6.9% (2.3–13.7). However, the heterogeneity among studies was found to be high. Various neurological manifestations related to the central nervous system (CNS) and peripheral nervous system (PNS) are associated with COVID-19 patients.

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Clinical characteristics, predictors of symptomatic coronavirus disease 2019 and duration of hospitalisation in a cohort of 632 Patients in Lagos State, Nigeria

Cited by 17 publications

References 4 publications

Clinical presentation and hospitalisation duration of 201 coronavirus disease 2019 patients in Abuja, Nigeria

Clinical presentation and hospitalisation duration of 201 coronavirus disease 2019 patients in Abuja, Nigeria

Neurological complications and effects of COVID-19: Symptoms and conceivable mechanisms

Neurological Manifestations in COVID-19 Patients: A Meta-Analysis

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