Clinical Characterization of Patients with Chronic Tension Headache

Langemark, Michael; Olesen, Jes; Poulsen, Dorte Loldrup; Bech, Per

doi:10.1111/j.1526-4610.1988.hed2809590.x

Cited by 75 publications

(43 citation statements)

References 19 publications

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“…Depression, anxiety, and medication overuse were predictors for a poor outcome. In a former cross-sectional clinical study, most of the patients with chronic tension-type headache had evolved from the episodic form during a period of many years [32], confirming numerous pathophysiologic studies that indicate that, on the basis of peripheral and central sensitization of the pain system, patients with frequent episodes of headache are at risk for suffering from chronic and treatment-resistant forms of tension-type headache [33][34][35].…”

Section: Epidemiologymentioning

confidence: 96%

Diagnosis, epidemiology, and impact of tension-type headache

Jensen

2003

Current Science Inc

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Although tension-type headache is the most prevalent headache and affects 78% of the general population, the substantial societal and individual burden associated with this primary headache has been overlooked. In contrast to migraine headache, there has been limited focus on tension-type headache. Most patients with the chronic form of tension-type headache, which affects 3% of the population, are left virtually without any specific treatment. Chronic tension-type headache differs from the episodic form in frequency, lack of effect to most treatment strategies, more medication overuse, and more loss of quality of life. Daily or near daily headaches also constitute a major diagnostic and therapeutic problem and distinguishing chronic tension-type headache from migraine headache and from medication-induced headache is a substantial diagnostic challenge because management strategies are completely different. Considerable benefits for the society can be gained by specific strategies leading to reductions in the amount of sickness absence and impaired working abilities. The burden on the affected patients' and their families' quality of life also may be improved by a general acceptance of the disorder and by the development of a specific treatment strategy.

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Section: Epidemiologymentioning

confidence: 96%

Diagnosis, epidemiology, and impact of tension-type headache

Jensen

2003

Current Science Inc

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“…It would also confirm reports of abnormal sensitivity to pain in paravertebral muscles [22] and a more rapid increase in pain in the fingers [20]. Pain thresholds to pressure are lower in the cranium than in the extremities [21].…”

Section: Pressure-pain Thresholdsmentioning

confidence: 56%

Central mechanisms in tension-type headaches

Vandenheede

Schoenen

2002

Current Science Inc

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Although tension-type headache is the most frequent primary headache, little is known about its pathophysiology. It is a matter of debate if the pain in tension-type headache originates from myofascial tissues or from central mechanisms in the brain. This article presents a summary of available data on the pathophysiology of tension-type headache and proposes a pathogenic model. From experimental research and clinical studies, it appears that myofascial nociception is important in episodic tension-type headache; however, central mechanisms (ie, central sensitization) are preponderant in the pathophysiology of the chronic form. Understanding the mechanisms of this central sensitization could allow for more efficient prophylactic treatments to emerge.

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“…A idade média para os homens com CTT episódica/crônica foi de 42,9/44,9 anos (mediana de 43/44 anos) e para mulheres 42,3/45,4 (mediana de 42/44). A idade média nos indivíduos com CTTC foi maior que nos indivíduos com CTTE, sugerindo que as formas crônicas possam se desenvolver a partir das formas episódicas 10 . A evolução de uma forma episódica para forma crônica geralmente se relaciona com o uso abusivo de analgésicos.…”

Section: Rasmussenunclassified

Avaliação clínica da eficácia da combinação paracetamol e cafeína no tratamento da cefaléia tipo tensão

Rabello

Forte

Galvão

2000

Arq. Neuro-Psiquiatr.

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RESUMO -A cefaléia tipo tensão em suas duas modalidades, episódica e crônica, é a forma mais comum de dor de cabeça na população. O tratamento é feito com medidas não farmacológicas e farmacológicas, tanto para o ataque como profilaxia das crises. Este estudo foi realizado com 5490 pacientes, que procuraram ambulatórios e consultórios médicos em várias regiões do Brasil. Cerca de 95% apresentavam cefaléia tipo tensão episódica e 5% cefaléia tipo tensão crônica. A maioria dos pacientes apresentou crises de intensidade moderada (62,19%). Em 5419 pacientes uma crise de cefaléia tipo tensão foi tratada com 1000 mg de paracetamol e 130 mg de cafeína. Em 93,98% início de melhora foi observado em até 2 horas após a ingestão da medicação. Em 77,61% houve reversão completa da crise em até 2 horas. Avaliação da eficácia boa/excelente foi observada em 51,93%/37,80% dos casos quando feita pelos médicos e em 48,51%/40,29 quando pelos pacientes. Efeitos adversos, em geral manifestações gastrointestinais, foram observados em 5,57%. Este estudo representa uma experiência brasileira no tratamento de ataque da cefaléia tipo tensão, demonstrando eficácia e segurança no uso da combinação paracetamol-cafeína. PALAVRAS-CHAVE: cefaléia, tratamento, paracetamol, cafeína. Clinical evaluation of the efficacy of the acetaminophen and caffeine combination in the treatment of tension headacheABSTRACT -Tension type headache in both its forms, episodic and chronic, is the most common type of headache experienced by the population. The headache attack or the prevention of new crises may be treated with pharmacological as well as non-pharmacological measures. This study included 5,490 patients from outpatient clinics and medical offices covering various regions of Brazil. Approximately 95% of the subjects had episodic tension type headache, while 5% had chronic tension type headache. The majority of the patients presented with crisis of moderate intensity (62.19%). In 5,419 patients a tension type headache crisis was treated with acetaminophen 1000 mg and caffeine 130 mg. In 93.98%, onset of relief occurred within 2 hours of taking the medication. In 77.61%, complete reversion of the crisis occurred within 2 hours. Good/excellent efficacy ratings were achieved in 61.93%/37.80% of the cases according to the physician's assessment and in 48.51%/40.29% according to the patients' assessment. Adverse events, commonly gastrointestinal manifestations, were reported by 5.57% of the patients. This is a Brazilian study of the efficacy and safety of the combined use of acetaminophen -caffeine for the treatment of tension type headache.KEY WORDS: headache, treatment, acetaminophen, caffeine.Cefaléia é qualquer dor referida no segmento cefálico. Trata-se de manifestação extremamente frequente na prática clínica, e alguns dados populacionais devem ser citados: -a prevalência de cefaléia durante a vida na população geral é maior que 90% 1 ; -em ambulatório geral de clínica

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Clinical Characterization of Patients with Chronic Tension Headache

Cited by 75 publications

References 19 publications

Diagnosis, epidemiology, and impact of tension-type headache

Diagnosis, epidemiology, and impact of tension-type headache

Central mechanisms in tension-type headaches

Avaliação clínica da eficácia da combinação paracetamol e cafeína no tratamento da cefaléia tipo tensão

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