Clinical classification of adult patients with chronic intestinal failure due to benign disease: An international multicenter cross-sectional survey

Pironi, Loris; Konrad, Denise; Brandt, Claus; Joly, Francisca; Wanten, Geert; Agostini, F.; Chambrier, C.; Aimasso, Umberto; Zeraschi, Sarah; Kelly, Darlene G.; Szczepanek, Kinga; Jukes, A.; Di, Simona; Theilla, Miriam; Kunecki, Marek; Daniels, Joanne; Serlie, Mireille J.; Poullenot, Florian; Wu, Jingxiang; Cooper, Sheldon C.; Rasmussen, Henrik; Compher, Charlene; Séguy, D.; Crivelli, Adriana; Pagano, Maria Carmen; Hughes, Sarah Jane; Guglielmi, Francesco William; Kozjek, Nada Rotovnik; Schneider, Stéphane; Gillanders, Lyn; Ellegård, Lars; Thibault, Ronan; Matras, Przemysław; Zmarzły, Anna; Matysiak, Konrad; Gossum, A. Van; Forbes, Alastair; Wyer, Nicola; Taus, Marina; Virgili, N.; O’Callaghan, Margie; Chapman, Brooke; Osland, Emma; Cuerda, C.; Sahin, Péter; Jones, Lynn; Lee, Andre D.W.; Bertasi, Valentino; Orlandoni, P.; Izbéki, Ferenc; Spaggiari, Corrado; Bueno, Marta; Doitchinova-Simeonova, Maryana; Garde, Carmen; Serralde‐Zúñiga, Aurora E.; Olveira, Gabriel; Krznarić, Željko; Czakó, László; Kėkštas, Gintautas; Sanz-París, A.; Jáuregui, Estrella Petrina; Murillo, Ana Zugasti; Schäfer, Eszter; Arends, Jann; Llanos, José Pablo Suárez; Shaffer, Jon; Lal, Simon

doi:10.1016/j.clnu.2017.04.013

Cited by 122 publications

(122 citation statements)

References 26 publications

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“…This international cross-sectional observational study comprises the largest study protocol approved by the Home Artificial Nutrition and Chronic Intestinal Failure (HAN&CIF) special interest group of ESPEN, which aims to investigate the applicability of the clinical classification of CIF [6]. The HPN centers' recruitment, the patient inclusion criteria, the modalities of data collection and the recorded items have been already extensively described [6] and are summarized below.…”

Section: Methodsmentioning

confidence: 99%

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Home parenteral nutrition provision modalities for chronic intestinal failure in adult patients: An international survey

Pironi¹,

Steiger

Brandt

et al. 2020

Clinical Nutrition

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Background and aim. The safety and effectiveness of an HPN program depends on both the expertise and the management procedures of the HPN center. We aimed to know the modalities needed to provide the home parenteral nutrition (HPN)-program and the types of intravenous supplementation (IVS)-admixtures supplied to patients with chronic intestinal failure (CIF) in different countries. Methods. In March 2015, 65 centers from 22 countries enrolled 3239 patients (benign disease 90.1%, malignant disease 9.9%), recording the patient, CIF and HPN characteristics in a structured database. The HPN-provider was categorized as health care system local pharmacy (LP) or home care company (HCC). The IVS-admixture was categorized as fluids and electrolytes alone (FE) or parenteral nutrition, either commercially premixed (PA) or customized to the individual patient (CA), alone or plus extra FE (PAFE or CAFE). Results. HPN-provider: HCC 66%, LP 34%; no difference between benign-CIF and malignant-CIF. LP was the main modality in 11 Countries; HCC prevailed in 4 European countries, Israel, USA, South America and Oceania (p<0.001). IVS-admixture: FE 10%, PA 17%, PAFE 17%, CA 38%, CAFE 18%. PA+PAFE use was greater in malignant-CIF and CA+CAFE use was greater in benign-CIF (p<0.001). PA+PAFE prevailed in those Countries where LP was the main HPN-provider and CA+CAFE prevailed where the main HPN-provider was HCC (p<0.001). Conclusions. The HPN provision and the IVS-admixture types differ greatly among countries, among HPN centers and between benign-CIF and malignant-CIF. As both HPN provider and IVS-admixture types may play a role in the safety and effectiveness of HPN therapy, criteria to homogenize HPN programs are needed, to give patients the same opportunity to receive appropriate HPN therapy.

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Section: Methodsmentioning

confidence: 99%

“…Demographic, clinical, CIF, underlying disease, IVS and HPN program characteristics were gathered, and the clinical classification of CIF was calculated for each patient [6]. The HPN-provider was categorized as health care system local pharmacy (LP) or home care company (HCC).…”

Section: Data Collection and Schedulementioning

confidence: 99%

Home parenteral nutrition provision modalities for chronic intestinal failure in adult patients: An international survey

Pironi¹,

Steiger

Brandt

et al. 2020

Clinical Nutrition

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“…Despite the excellent data and knowledge gained from these registries, a significant gap remains in our knowledge of clinical outcomes among patients receiving HPN, demographics, and the true number of patients receiving HPN within the United States. Pironi et al and international HPN centers recently participated in a survey to understand the classification and characteristics of patients with chronic IF 72 …”

Section: Longitudinal Hpn Registriesmentioning

confidence: 99%

Overview of Home Parenteral Nutrition: An Update

et al. 2017

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The trend in modern medicine is to transition care from the hospital to home or other nonacute settings as soon as possible. Increasingly, nutrition support professionals are being asked to help facilitate discharge and/or manage patients who require prolonged intravenous fluid and/or nutrition after having been stabilized during a hospitalization. This updated tutorial reviews many of the concepts and challenges that must be considered for successful care that helps to focus on the patients and their quality of life.

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“…Es causa importante de falla intestinal crónica o tipo III, donde los cambios estructurales y funcionales favorecen la malabsorción, el riesgo de deficiencias severas de micronutrientes y la inhibición del proceso de desarrollo y crecimiento. La incidencia de síndrome de intestino corto es de aproximadamente 2 casos por millón por año y la prevalencia se sitúa en torno a 20 casos por millón (1)(2)(3)(4) . La falla intestinal crónica se produce cuando fracasa la fase de adaptación del síndrome de intestino corto (1) .…”

Section: Introductionunclassified

Dependiendo de la nutrición parenteral para sobrevivir. Falla intestinal crónica por síndrome de intestino corto. Comunicación de un caso y revisión de la literatura

Moreira

López

Silva

et al. 2019

REVISTA MEDICA DEL URUGUAY

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Cuando la falla intestinal ocurre luego de una resección intestinal masiva se denomina síndrome de intestino corto. Es una entidad rara, con un espectro clínico que va desde una disfunción leve y reversible hasta una condición grave e incapacitante. Presenta una elevada morbimortalidad, altos costos de atención médica e importante impacto en la calidad de vida. El 50% de los pacientes con síndrome de intestino corto no se adaptan espontáneamente ni mejoran la absorción por el intestino remanente, por lo que deben recurrir de por vida a la nutrición parenteral. La terapia nutricional especializada y el tratamiento hormonal focalizado en el intestino son pilares en la rehabilitación promoviendo la adaptación intestinal, logrando independencia de la nutrición parenteral y evitando el trasplante intestinal. Actualmente, teduglutide es el tratamiento de referencia en estos pacientes, pero hasta el momento inaccesible en Uruguay por su elevado costo. Presentamos el único caso en nuestro país de un paciente de 23 años portador de falla intestinal crónica por síndrome de intestino corto que depende de la nutrición parenteral desde hace 17 años y presenta complicaciones graves asociadas a esta técnica. Palabras clave: Síndrome del intestino corto Nutrición parenteral Teduglutida Fallo intestinal Enfermedad crónica

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Clinical classification of adult patients with chronic intestinal failure due to benign disease: An international multicenter cross-sectional survey

Cited by 122 publications

References 26 publications

Home parenteral nutrition provision modalities for chronic intestinal failure in adult patients: An international survey

Home parenteral nutrition provision modalities for chronic intestinal failure in adult patients: An international survey

Overview of Home Parenteral Nutrition: An Update

Dependiendo de la nutrición parenteral para sobrevivir. Falla intestinal crónica por síndrome de intestino corto. Comunicación de un caso y revisión de la literatura

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