1998
DOI: 10.1016/s0143-4004(98)90100-x
|View full text |Cite
|
Sign up to set email alerts
|

Clinical correlations of patterns of placental pathology in preterm pre-eclampsia

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2
1

Citation Types

0
19
0
4

Year Published

2002
2002
2014
2014

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 92 publications
(23 citation statements)
references
References 22 publications
0
19
0
4
Order By: Relevance
“…An example of a normotensive, mature placenta is shown with little/no Flt/sFlt-1 staining (E, ×50). particularly those that are delivered preterm (less than 37 weeks' gestation), are usually small and show accelerated villous maturation [17]. This hypermaturity is characterized by the presence of syncytial knots, above and beyond what is normal for gestational age [11].…”
Section: Discussionmentioning
confidence: 99%
“…An example of a normotensive, mature placenta is shown with little/no Flt/sFlt-1 staining (E, ×50). particularly those that are delivered preterm (less than 37 weeks' gestation), are usually small and show accelerated villous maturation [17]. This hypermaturity is characterized by the presence of syncytial knots, above and beyond what is normal for gestational age [11].…”
Section: Discussionmentioning
confidence: 99%
“…For example, in pre-eclampsia, spiral arteries remain 'untransformed' [10], remaining muscular due to the incomplete invasion of trophoblast, leading to high-resistance blood flow passing through these vessels and abnormal uteroplacental blood flow. Though ischaemic-type changes have been observed in the majority of severe preterm cases [8,11], there may be subjectively normal placental histological findings even in cases of clinically severe disease at or near term [12,13]. Features such as infarction, extensive perivillous fibrin deposition and chronic villitis are more frequent in SGA in some studies [14] but not others [15] and are well-reported in clinically normal pregnancies.…”
Section: Introductionmentioning
confidence: 99%
“…(Brosens and Renaer 1972;Teasdale 1985;Sodhi et al 1990;Salafia et al 1995;Salafia et al 1998;Sekotory and Ahmed 2001;Sikkema et al 2002) Although not specific for preeclampsia, infarcts, when large, central or multiple, indicate significant uteroplacental disease (Fox 1997). We have noted anecdotally that the placenta may often demonstrate few diagnostic pathological features in cases delivered near term even in the presence of severe clinical disease according to the criteria for induced or operative delivery.…”
Section: Introductionmentioning
confidence: 99%