Clinical Course of Children 1 to 24 Months Old With Positive Urine Cultures Without Pyuria

Wang, Marie E.; Jones, Veena G.; Kane, Miranda; Allan, Jessica M.; Maleknia, Lydia; Patel, Ritu; Ip, Wui; Newman, Thomas B.; Roberts, Kenneth B.; Schroeder, Alan R.

doi:10.1016/j.acap.2023.06.023

Academic Pediatrics

2024

DOI: 10.1016/j.acap.2023.06.023

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Clinical Course of Children 1 to 24 Months Old With Positive Urine Cultures Without Pyuria

Marie E. Wang

Veena G. Jones²,

Miranda Kane³

et al.

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2024

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Cited by 2 publications

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Clinical outcomes in febrile children with a positive urine culture without pyuria: Implications for antibiotics

Miyake,

Hataya

2024

Acta Paediatrica

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AimThis study aimed to investigate whether antibiotics should be administered to patients aged <2 years with a positive urine culture without pyuria by identifying their clinical characteristics and outcomes in the absence of antibiotic treatment.MethodsThis retrospective, observational study included children aged <2 years with positive findings on a culture of urine obtained using a catheter in the paediatric emergency department between 2016 and 2021. The primary outcome was the spontaneous resolution of fever without antibiotics in patients with a positive urine culture without pyuria. The clinical characteristics of the patients with and without pyuria were also compared.ResultsOf 391 patients, 86 (22%) were negative for pyuria. Of these, 63 (73%) received no antibiotics, and 56 (89%) had spontaneous defervescence and no symptom recurrence. The patients without pyuria had a higher proportion of other possible causes of fever, lower inflammatory markers, fewer cultured bacteria, and a higher proportion of multiple, bacterial species in their culture than the patients with pyuria.ConclusionsMost of the patients with a positive urine culture without pyuria may not require antibiotics if their fever resolves spontaneously.

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Clinical outcomes in febrile children with a positive urine culture without pyuria: Implications for antibiotics

Miyake,

Hataya

2024

Acta Paediatrica

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Mislabeled Bag Urine Cultures and Antibiotic Treatment Decisions

Liang,

Schroeder,

Maleknia

et al. 2024

Pediatrics

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Clinical Course of Children 1 to 24 Months Old With Positive Urine Cultures Without Pyuria

Cited by 2 publications

References 34 publications

Clinical outcomes in febrile children with a positive urine culture without pyuria: Implications for antibiotics

Clinical outcomes in febrile children with a positive urine culture without pyuria: Implications for antibiotics

Mislabeled Bag Urine Cultures and Antibiotic Treatment Decisions

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