Clinical Cytology in the Diagnosis and Management of Melanoma

Siddaraju, Neelaiah

doi:10.5772/18114

Cited by 5 publications

(5 citation statements)

References 81 publications

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“…Primary and metastatic malignant melanoma may assume histological pattern which makes the light-microscopic identification of the tumours difficult, or even impossible especially when they are amelanotic cells which mimic those of sarcoma or carcinoma [1,8]. Most important the investigation to distinguish melanomas from other tumours is immunohistochemistry.…”

Section: Discussionmentioning

confidence: 99%

Metastatic Amelanotic Melanoma with Occult Primary Masquerading as Sarcoma

Ahmed

Kurpad

2015

JCDR

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Section: Discussionmentioning

confidence: 99%

Metastatic Amelanotic Melanoma with Occult Primary Masquerading as Sarcoma

Ahmed

Kurpad

2015

JCDR

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“…However, diagnosis of the amelanotic variant on cytology is challenging because in the absence of pigment, the tumor cells mimic those of carcinoma or sarcoma, like in our case. [ 4 ]…”

Section: Discussionmentioning

confidence: 99%

Amelanotic melanoma masquerading as a superficial small round cell tumor: A diagnostic challenge

et al. 2014

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Malignant melanoma poses a remarkable capacity for morphological diversity and often presents as a diagnostic challenge due to its wide clinical presentation. We present a case of a 73-year-old lady, with a large superficial ulcerative nodular mass on the flexor aspect of the right upper arm. On fine needle aspiration poorly differentiated round cell tumor was suggested, with histopathology also supporting the same diagnosis. A final diagnosis of amelanotic melanoma was given following immunohistochemical work-up using a panel of relevant markers. We are presenting this case, not only for its rare clinical presentation, but also for the diagnostic difficulties encountered by us in cytology and histopathology to reach the final diagnosis.

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“…Melanoma infiltrating bone marrow is a very unusual event of established poor prognosis . It is a well known fact that cytologic samples obtained from fine needle or aspiration of biological fluids affected by metastatic melanomas may show a blackish appearance . Differential diagnosis of black pigmentation in bone marrow includes, in addition to melanoma metastases, rare entities such as bone marrow anthracosis or the presence of metallic wear debris in bone marrow coming from the site of a severely worn joint implant …”

Section: Discussionmentioning

confidence: 99%