Clinical Detection of Melanoma-Associated Spongiform Scleropathy by Ultrasound Biomicroscopy and Its Correlation With Pathological Diagnosis

Weisbrod, Daniel J.

doi:10.1001/archophthalmol.2009.162

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…The pre-enucleation ultrasound biomicroscopic features of melanoma-associated spongiform scleropathy have been reported once [10] . We are not aware of this type of spongiform scleral degeneration occurring in any other disorder than in choroidal and ciliary body melanoma.…”

Section: Discussionmentioning

confidence: 99%

Melanoma-Associated Spongiform Scleropathy in Oculodermal Melanocytosis with Primary Orbital Melanoma

2016

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Purpose: To describe spongiform scleropathy in a patient with oculodermal melanosis and without evidence of uveal melanoma. Methods: Clinical-pathological correlation conducted in compliance with HIPPA (Health Insurance Privacy and Portability Act) regulations. Results: Melanoma-associated spongiform scleropathy was an incidental finding in an 87-year-old woman with oculodermal melanocytosis treated for primary orbital melanoma. All previously reported cases of this scleropathy have been associated with uveal melanoma. Conclusions: The mechanism of scleral degeneration in melanoma-associated spongiform scleropathy is unknown, and its clinical and prognostic significance is speculative. This is the first case of a so-called melanoma-associated spongiform scleropathy reported in an eye without uveal melanoma.

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Section: Discussionmentioning

confidence: 99%

Melanoma-Associated Spongiform Scleropathy in Oculodermal Melanocytosis with Primary Orbital Melanoma

2016

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Melanoma-associated spongiform scleropathy

Das

Bhattacharjee

Barman

et al. 2021

Indian Journal of Ophthalmology - Case Reports

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Melanoma-associated spongiform scleropathy (MASS) is a non-inflammatory scleral degenerative change with a spongiotic morphology seen in the sclera associated with uveal melanoma. This degenerative change was seen in the inner side of the sclera in contact with the pigmented mass. It is usually seen in an elderly person with choroidal melanoma. We report a case of MASS in a large choroidal melanoma in a 58-year-old Indian man supported by histopathology, special histochemical stains, and immunohistochemistry.

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Clinical Detection of Melanoma-Associated Spongiform Scleropathy by Ultrasound Biomicroscopy and Its Correlation With Pathological Diagnosis

Cited by 2 publications

References 6 publications

Melanoma-Associated Spongiform Scleropathy in Oculodermal Melanocytosis with Primary Orbital Melanoma

Melanoma-Associated Spongiform Scleropathy in Oculodermal Melanocytosis with Primary Orbital Melanoma

Melanoma-associated spongiform scleropathy

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