2016
DOI: 10.2967/jnumed.115.157834
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Clinical Diagnosis and Management of Breast Cancer

Abstract: The diagnosis and management of breast cancer are undergoing a paradigm shift from a one-size-fits-all approach to an era of personalized medicine. Sophisticated diagnostics, including molecular imaging and genomic expression profiles, enable improved tumor characterization. These diagnostics, combined with newer surgical techniques and radiation therapies, result in a collaborative multidisciplinary approach to minimizing recurrence and reducing treatment-associated morbidity. This article reviews the diagnos… Show more

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Cited by 420 publications
(302 citation statements)
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“…However, the applicability of all these processes is often limited by heavy toxicity, poor efficacy, therapeutic resistance, and morbidity. For this reason, strictly effective methods for combating breast cancer‐related diseases and deaths are necessary . Biochemical detection of this cancer is based on the identification of markers including cancer antigen 27‐29 (CA 27‐29), CA 15‐3, and carcinoembryonic antigen .…”
Section: Introductionmentioning
confidence: 99%
“…However, the applicability of all these processes is often limited by heavy toxicity, poor efficacy, therapeutic resistance, and morbidity. For this reason, strictly effective methods for combating breast cancer‐related diseases and deaths are necessary . Biochemical detection of this cancer is based on the identification of markers including cancer antigen 27‐29 (CA 27‐29), CA 15‐3, and carcinoembryonic antigen .…”
Section: Introductionmentioning
confidence: 99%
“…Furthermore, the effects of these drugs may not completely eliminate the chances of getting breast cancer. Therefore, there is a scope in this indication for newer interventions (McDonald et al, 2016). …”
Section: Introductionmentioning
confidence: 99%
“…However, applicability of all these modalities is mostly limited by their inordinate toxicity, inadequate efficacy, therapeutic resistance and treatment-related morbidity. Thus, further effective modalities are definitely required to fight against diseases and deaths associated with breast cancer (McDonald et al, 2016). …”
Section: Introductionmentioning
confidence: 99%
“…Within the field of oncology, personalized medicine is at the forefront of cancer diagnosis and treatment. For example, cancer-specific biomarkers can be used to diagnose different cancer types [7]. In addition, mutational profiles of tumors can guide treatment options and help detect resistance to treatments, enabling physicians to evaluate therapeutic options quickly and effectively [8].…”
Section: Introductionmentioning
confidence: 99%