Clinical diagnosis of 80 cases of dementia in a university hospital

Abstract

Objective: This study aims to estimate the prevalence of dementia subtypes and to assess the socio-demographic data of patients attending the outpatient clinic of dementia at Hospital das Clínicas from January 2008 to December 2009, in the city of Goiânia-GO, Brazil. Methods: Procedures provided for diagnosis included physical and neurological examination, laboratory tests, neuroimaging and DSM-IV. The functional capacity and level of cognitive deficit were assessed by Pfeffer Functional Activities Questionnaire (Pfeffer-FAQ) and Mini--Mental State Examination (MMSE), respectively. results: Eighty patients met the criteria for dementia. The mean age was 63.48 (± 16.85) years old, the schooling was 3.30 (± 3.59) years old, the MMSE was 13.89 (± 7.79) and Pfeffer 17.73 (± 9.76). The Vascular Dementia (VD; 17.5%) was the most frequent cause of dementia, followed by Lewy body dementia (LBD) and Alzheimer's disease (AD) (12.25%). conclusion: Considering entire sample and only the elderly over 60 years, VD, AD and LBD are the most common subtypes observed at both groups. Further epidemiological studies are necessary to confirm such rates, which may have a considerable impact on the organization and planning of healthcare services in our country. reSUMO Objetivo: Este estudo tem como objetivo estimar a prevalência dos subtipos de demência e avaliar os dados sociodemográficos dos pacientes atendidos no ambulatório de demências do Hospital das Clínicas, de janeiro de 2008 a dezembro de 2009, na cidade de Goiânia--GO, Brasil. Métodos: Os procedimentos incluídos para realização do diagnóstico incluíram exame físico e neurológico, exames laboratoriais, de neuroimagem e DSM-IV. A capacidade funcional e o nível de déficit cognitivo foram avaliados por questionário de atividades funcionais (Pfeffer) e Miniexame do Estado Mental (MEEM), respectivamente. resultados: Oitenta pacientes preencheram os critérios para demência. A idade média foi de 63,48 (± 16,85) anos; a escolaridade foi de 3,30 (± 3,59) anos; o MEEM foi de 13,89 (± 7,79) e o Pfeffer foi de 17,73 (± 9,76). A demência vascular (DV; 17,5%) foi a causa mais frequente de demência, seguida

Diagnosis and management of Parkinson’s disease dementia and dementia with Lewy bodies: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

“…In tertiary centers-based studies, the frequency of these two etiologies ranged from 3.7% to 15% of cases [9][10][11][12][13] Similarly, a study based on neuropathological diagnosis cases 14 showed that LBD caused 15% of cases of dementia, whether isolated or associated with other pathologies. LBD was also the second most frequent neurodegenerative etiology of dementia and related to a higher risk of dementia with an odds ratio (OR) of 3.4 (CI: 1.94-5.97).…”

Diagnóstico e manejo da demência da doença de Parkinson e demência com corpos de Lewy: recomendações do Departamento Científico de Neurologia Cognitiva e do Envelhecimento da Academia Brasileira de Neurologia

“…A DDP representa 13,5% dos casos de parkinsonismo com demência 6 , enquanto a DCL é responsável por menos de 5% das etiologias 7,8 . Em estudos baseados nas casuísticas de centros terciários, a prevalência dessas duas etiologias varia entre 3,7 a 15% [9][10][11][12][13] dos casos de demência. Esses dados são similares aos observados em estudo neuropatológico prévio, em que a DCL foi responsável por 15% das etiologias de demência, seja de forma isolada ou associada a outras patologias 14 .…”

<strong>Dengue Fever and Neurology: Well Beyond Hemorrhage and Strokes</strong>

“…In children, a study with 71 confirmed cases showed that 28.17% of the patients had neurological involvement 13 . Another study evaluating 74 patients with possible viral associated neurological complications in Brazil found that 11% of those cases had relationship with DF 14 .…”