Clinical diagnosis of cholecystitis in emergency department patients with cholelithiasis is indication for urgent cholecystectomy: A comparison of clinical, ultrasound, and pathologic diagnosis

Martin, W. Taylor; Stewart, Katharine E.; Sarwar, Zoona; Kennedy, Ryan; Quang, Celia Y.; Albrecht, Roxie M.; Cross, Alisa

doi:10.1016/j.amjsurg.2022.02.051

Cited by 9 publications

(2 citation statements)

References 13 publications

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“…The second stage of gastrointestinal tract with single calculi, which were of pigment origin and most often localized in the gallbladder, was recorded more often. More than half of the examined children were characterized by s-shaped deformation of the gallbladder, which is consistent with the results of other studies [16,18,27].…”

Section: Cg N=25supporting

confidence: 91%

“…Gallstone disease occurs more often in schoolaged children, among children up to 7 years old, boys are twice as often affected as girls, at the age of 7-9 years there are no gender differences in the frequency of the disease, at the age of 10-12 years, girls are affected twice as often as boys. Most children have bilirubin calculi before puberty, and cholesterol calculi in puberty and adolescence [16,17,18]. Dyscholia of hepatic genesis, cholestasis and inflammation are the main factors in the formation of cholelithiasis in children.…”

Section: рівень цинку в плазмі крові та перебіг жовчнокам'яної хвороб...mentioning

confidence: 99%

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The Level of Zinc in Blood Plasma and the Course of Gallstone Disease in Children

Sorokman¹,

Ostapchuk

2023

Buk. Med. Herald

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Determining the zinc level in children's blood plasma is an urgent problem, given its possible participation in the formation of cholelithiasis.Aim. To investigate the level of zinc in the blood plasma and the clinical course of gallstone disease (GSD) in children.Methods. 69 children aged 10-17 years and 25 children without biliary tract pathology were selected by the method of simple randomization. Verification of the diagnosis was carried out by applying dynamic ultrasound examination and X-ray examination of the organs of the abdominal cavity. Quantitative determination of zinc in blood plasma was carried out using mass spectrometry.Results. Dysfunction of the biliary tract according to the hyperkinetic type occurred in 55.1±7.1% of children and according to the hypokinetic type in 44.9±3.9%. The asymptomatic variant of housing and communal services was observed in 23.9%, painful - in 54.3% of patients, paroxysmal - in 21.7% of patients. The plasma concentration of zinc in children with gastrointestinal diseases was 1.87 times lower than in children of the comparison group and 1.37 times lower than in children with hyperkinetic gallbladder dysfunction, while there was a probable difference between these indicators in children with housing and communal services and in children with the hypotonic type of gallbladder dysfunction (p<0.05).Conclusions. 1. The leading syndromes of gallstone disease in children were pain and dyspepsia. 2. Gallstone disease in children occurs against the background of gallbladder dysfunction with a predominance of the painful course, the formation of solitary bilirubin-derived concretions and minor changes in biochemical blood analysis. 3. The concentration of zinc in the blood plasma of children with gallstone disease is probably lower than in children of the comparison group and does not depend on age and gender.

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Section: Cg N=25supporting

confidence: 91%

Section: рівень цинку в плазмі крові та перебіг жовчнокам'яної хвороб...mentioning

confidence: 99%

The Level of Zinc in Blood Plasma and the Course of Gallstone Disease in Children

Sorokman¹,

Ostapchuk

2023

Buk. Med. Herald

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Computed tomography versus ultrasound for the diagnosis of acute cholecystitis: a systematic review and meta-analysis

de Oliveira,

Torri,

Gandolfi

et al. 2024

Eur Radiol

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Not all cholecystitis is created equal: Disparities contributing to ED presentation and failure of the outpatient algorithm

Martin

Ball

Patterson

et al. 2023

The American Journal of Surgery

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Clinical diagnosis of cholecystitis in emergency department patients with cholelithiasis is indication for urgent cholecystectomy: A comparison of clinical, ultrasound, and pathologic diagnosis

Cited by 9 publications

References 13 publications

The Level of Zinc in Blood Plasma and the Course of Gallstone Disease in Children

The Level of Zinc in Blood Plasma and the Course of Gallstone Disease in Children

Computed tomography versus ultrasound for the diagnosis of acute cholecystitis: a systematic review and meta-analysis

Not all cholecystitis is created equal: Disparities contributing to ED presentation and failure of the outpatient algorithm

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