Clinical Differences Between Elderly and Non-elderly Patients with COVID-19

Üçsular, Fatma Demirci; Karadeniz, Gülistan; Polat, Gülru; Ayrancı, Aysu; Yalnız, Enver; Kazankaya, Fatmanur; Güldaval, Filiz; Büyükşirin, Melih; Anar, Ceyda

doi:10.5152/turkthoracj.2022.21288

Cited by 2 publications

(2 citation statements)

References 21 publications

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“…Nowadays, although we have safely passed the most menacing stage of COVID-19, the protective effect of the SARS-CoV-2 vaccine is weakening over time ( 44 ), and there are still many individuals experiencing multiple infections due to SARS-CoV-2. In our study, as well as in previous studies, older adults with the presence of underlying diseases remain the most prominent victims of COVID-19 ( 40 , 45 , 46 ). Therefore, now, half a year after the peak of COVID-19, we still call on the public to strengthen awareness of prevention and to receive timely vaccination or catch-up vaccination when the situation permits in order to minimize the damage to health caused by COVID-19.…”

Section: Discussionsupporting

confidence: 87%

Effect of the number of coronavirus disease 2019 (COVID-19) vaccination shots on the occurrence of pneumonia, severe pneumonia, and death in SARS-CoV-2-infected patients

Xin,

Chen,

et al. 2024

Front. Public Health

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BackgroundCoronavirus disease (COVID-19) has posed a significant threat to the lives and health of people worldwide since its onset in 2019. However, the relationship between the number of vaccination shots and the severity of SARS-CoV-2 infection in Chinese patients remains unclear.MethodsWe retrospectively collected information from 829 patients infected with SARS-CoV-2 in Ningbo Medical Center Lihuili Hospital from December 05, 2022 to March 31, 2023, then divided them into four groups based on the severity of pneumonia. Last, we compared the difference in the number of shots of COVID-19 vaccine between the four groups, considering potential confounding factors using univariate and multivariate logistic regression.ResultsVaccination with two and three doses was positively associated with low prevalence of pneumonia and severe pneumonia both in crude and optimal models, while only three doses of the vaccine was correlated with low prevalence of death in SARS-CoV-2-infected patients. In optimal models, male SARS-CoV-2-infected individuals with advanced age were positively associated with high prevalence of pneumonia, severe pneumonia, and death; comorbidity with hypertension (OR = 2.532, p < 0.001) was positively associated with high prevalence of pneumonia (OR = 2.532, p < 0.001); and comorbidity with diabetes was positively associated with high prevalence of death (OR = 1.856, p = 0.011). However, this is a cross-sectional study and the causal relationships need to be further studied.ConclusionOne dose of vaccine may not have a protective effect against pneumonia, severe pneumonia, and death; more than one dose of vaccine is an independent protective factor for pneumonia and severe pneumonia; and three doses of vaccine is an independent protective factor for death.

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Section: Discussionsupporting

confidence: 87%

Effect of the number of coronavirus disease 2019 (COVID-19) vaccination shots on the occurrence of pneumonia, severe pneumonia, and death in SARS-CoV-2-infected patients

Xin,

Chen,

et al. 2024

Front. Public Health

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“…Similar to our results, Péterfi et al identified that COPD, hypertension, and diabetes are the risk factors for a higher number of hospitalizations among older patients with COVID-19 [ 25 ]. Üçsular et al [ 26 ], who carried out a retrospective study, showed that hypertension, COPD, diabetes, and cardiovascular disease in the elderly were significantly higher compared to the non-elderly. In addition, most of the elderly underwent hospital treatment in the ward and ICU.…”

Section: Discussionmentioning

confidence: 99%

Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational Study

Cavallari Strozze Catharin,

Zutin,

Guiguer

et al. 2023

Diseases

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COVID-19 has generated a scenario for global health with multiple systemic impairments. This retrospective study evaluated the clinical, radiological, and pulmonary functional evolution in 302 post-COVID-19 patients. Regarding post-COVID-19 pulmonary symptoms, dry cough, dyspnea, and chest pain were the most frequent. Of the associated comorbidities, asthma was more frequent (23.5%). Chest tomography (CT) initially showed a mean pulmonary involvement of 69.7%, and evaluation in the subsequent months showed improvement in the evolutionary image. With less than six months post-pathology, there was a commitment of 37.7% from six to twelve months it was 20%, and after 12 months it was 9.9%. As for most of the sample, 50.3% of the patients presented CT normalization less than six months after infection, 23% were normalized between six and twelve months, and 5.2% presented with normalized images after twelve months, with one remaining. A percentage of 17.3% maintained post-COVID-19 pulmonary residual sequelae. Regarding spirometry, less than six months after pathology, 59.3% of the patients presented regular exam results, 12.3% had their function normalized within six to twelve months, and 6.3% had normal exam results twelve months after their post-pathology evaluation. Only 3.6% of the patients still showed some alteration during this period.

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Clinical Differences Between Elderly and Non-elderly Patients with COVID-19

Cited by 2 publications

References 21 publications

Effect of the number of coronavirus disease 2019 (COVID-19) vaccination shots on the occurrence of pneumonia, severe pneumonia, and death in SARS-CoV-2-infected patients

Effect of the number of coronavirus disease 2019 (COVID-19) vaccination shots on the occurrence of pneumonia, severe pneumonia, and death in SARS-CoV-2-infected patients

Radiological and Functional Pulmonary Evolution in Post-COVID-19 Patients: An Observational Study

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