Clinical Effect of Amiodarone in the Treatment of Senile Congestive Heart Failure with Ventricular Arrhythmia

Abstract

To analyze the clinical effect of amiodarone in the treatment of congestive heart failure with ventricular arrhythmias in the elderly is the objective of the study. A total of 62 elderly patients with congestive heart failure complicated with ventricular arrhythmia who received treatment in our hospital from January 2020 to June 2021 were enrolled and randomly divided into conventional group and amiodarone group. The conventional group was given diuretic and cardiotonic treatment, while the amiodarone group was given amiodarone treatment on the basis of the conventional group. The efficacy of congestive heart failure with ventricular arrhythmias, adverse drug reactions, cardiac index, heart rate, left ventricular end-diastolic, left ventricular ejection fraction, tachycardia, ventricular precontraction and QT (min) before and after the intervention, time to electrocardiogram normalization, and time to discharge were compared between the two groups. The efficacy of congestive heart failure with ventricular arrhythmia was higher in the amiodarone group than in the conventional group (p<0.05); no serious adverse drug reactions occurred in both groups, and the difference was not statistically significant; cardiac index, heart rate, left ventricular end-diastolic and left ventricular ejection fraction were similar in the two groups before the intervention, and the difference was not statistically significant; cardiac index, heart rate, left ventricular end-diastolic, and left ventricular ejection fraction were better in the amiodarone group than in the conventional group at discharge (p<0.05). Tachycardia episodes, ventricular precontraction and QT (min) were similar between the two groups before the intervention and the differences were not statistically significant; tachycardia episodes, ventricular precontraction and QT (min) were better in the amiodarone group than in the conventional group at the time of discharge (p<0.05). The amiodarone group had a shorter time to electrocardiogram reversion and discharge than the conventional group (p<0.05). Amiodarone is clinically effective and safe in the treatment of congestive heart failure with ventricular arrhythmias in the elderly, and it can effectively improve cardiac function, restore electrocardiogram and vital signs, and shorten hospitalization time, so it is worth promoting its application.