Clinical effect of autologous platelet-rich fibrin in the treatment of intra-bony defects: a controlled clinical trial

Thorat, Manojkumar; Pradeep, A.R.; Pallavi, Borse

doi:10.1111/j.1600-051x.2011.01760.x

Cited by 189 publications

(212 citation statements)

References 34 publications

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“…8,9 PRF has been used in different surgical procedures such as sinus floor augmentation, treatment of gingival recession (GR), furcation defects, maxillary rehabilitation before implant placement, restoration of peri-implant defects, as well as healing of extraction sockets with promising results. 10,11,12,13,14 In addition, certain clinical studies have been conducted on the use of PRF for treatment of intra-bony defects in humans, 15,16,17,18,19 but none have investigated its additive effects with ABBM for treatment of intra-bony defects. Thus, the present split-mouth, single-centre, controlled study aimed to compare the healing of intra-bony defects treated with a combination of ABBM-PRF or ABBM alone; the hypothesis being tested was that PRF would augment the regenerative effects of ABBM in human intra-bony defects.…”

Section: Introductionmentioning

confidence: 99%

“…These results are in concordance with those of the aforementioned studies. 36,37 Several studies 15,16,17,38 have examined the suitability of autologous PRF for treatment of human intra-bony defects and revealed that PRF improves clinical 15 and radiographical 15,16,17,38 parameters. However, in the present study, no statistically significant differences were observed between both groups, except for the significant CAL gain noted in the test group.…”

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confidence: 99%

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Effects of platelet-rich fibrin on healing of intra-bony defects treated with anorganic bovine bone mineral

et al. 2017

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Anorganic bovine bone mineral (ABBM) is extensively used in the treatment of intra-bony defects. Platelet-rich fibrin (PRF) is a new-generation platelet concentrate with a simplified technique. Although certain studies have reported the use of PRF in the treatment of intra-bony defects, to date, none of them have evaluated its additive effects with ABBM. Therefore, a randomised, split-mouth clinical trial was conducted to compare healing of intra-bony defects treated with an ABBM-PRF combination with healing of those treated with ABBM alone. By using a split-mouth design, 15 paired intra-bony defects were randomly treated with either ABBM alone (control group) or ABBM-PRF combination (test group). Following clinical parameters and radiographical measurements were recorded at baseline and 6 months after treatment: plaque index (PI), gingival index (GI), probing depth (PD), gingival recession (GR), clinical attachment level (CAL), vertical bone loss, depth of defect and defect angle. Preoperative clinical and radiographical measurements were similar for the test and control groups. Statistically significant reductions in GI, PD, CAL, vertical bone loss, depth of intra-bony defect and widening of defect angle were detected after treatment in both groups. With respect to inter-group analysis, gain in CAL was significantly greater in the test group than in the control group, whereas no inter-group differences were observed in any other parameter. The results of this study indicate that both therapies are effective in the treatment of intra-bony defects.

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Section: Introductionmentioning

confidence: 99%

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confidence: 99%

Effects of platelet-rich fibrin on healing of intra-bony defects treated with anorganic bovine bone mineral

et al. 2017

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“…As a result of treatment and 12 months follow-up, the defect was almost completely eliminated and satisfactory healing of periodontal tissues was observed. In the literature, there are also existing reports utilizing the required size PRF as filler into the infrabony defect and also placing the remaining part of the material to cover the same region as a barrier, successfully [26,27].…”

Section: Discussionmentioning

confidence: 99%

Management of Two-Wall Infra-Bony Defect with Platelet Rich Fibrin and Connective Tissue Graft Combination: A Case Report

Keçeli¹

2015

J Dent Probl Solut

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Background: Regenerative procedures offer a limited potential toward achieving a complete periodontal regeneration and today, there is not any single material that can be considered as 'gold standard' in infra bony defect treatment. Platelet-rich fibrin (PRF) is the second-generation platelet concentrate and represents a slow release system for growth factors. Use of PRF showed promising results in various periodontal surgical procedures. The aim of this report is to describe two-stage treatment of a canine tooth having an infrabony defect accompanied with a deep dehiscence by using PRF-connective tissue graft (CTG) combination.Case Report: A 28-year old man was referred to the Department of Periodontology with chief complaints of purulent exudate formation, tooth mobility in tooth #23 (FDA classification). Deep periodontal pockets in combination with 4 mm buccal recession were detected. Radiographically, a significant radiolucency was also present. CTG graft combined with coronally advanced flap by adding a PRF gel was utilized for the treatment of defect and accompanying gingival recession. Conclusion:Significant improvements were detected at all periodontal clinical and radiographic measurements.

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“…Un solo estudio trató defectos de 3 paredes (18) mientras que los otros 2 abordaron defectos de 2 y 3 paredes conjuntamente (19,20) . En el trabajo de Thorat y col. (2011), casi el 70% de los sitios correspondieron a 3 paredes (20) .…”

Section: ) L-prf Vs Colgajo De Acceso Periodontal (Cpa)unclassified

Revisión Bibliográfica

Mayol

Andrade

Retamal‐Valdes

et al. 2018

Rev. Clin. Periodoncia Implantol. Rehabil. Oral

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Clinical effect of autologous platelet-rich fibrin in the treatment of intra-bony defects: a controlled clinical trial

Abstract: Within the limit of the present study, there was greater reduction in PD, more CAL gain and greater intra-bony defect fill at sites treated with PRF than the open flap debridement alone.

Cited by 189 publications

References 34 publications

Effects of platelet-rich fibrin on healing of intra-bony defects treated with anorganic bovine bone mineral

Effects of platelet-rich fibrin on healing of intra-bony defects treated with anorganic bovine bone mineral

Management of Two-Wall Infra-Bony Defect with Platelet Rich Fibrin and Connective Tissue Graft Combination: A Case Report

Revisión Bibliográfica

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