“…(b) It results in clinically relevant improvements in multiple biomarker risk factors (including systolic and diastolic blood pressure, total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, fasting glucose, body weight, body mass index, waist circumference, and cardiorespiratory fitness) in diverse populations. These populations include male and female patients, 25-28 African Americans and Caucasians, 19,29-31 educated and less-well-educated participants, 32 and apparently healthy participants as well as those with a variety of chronic medical conditions (including overweight/obesity, 33,34 prediabetes/diabetes, 18,25,35-37 prehypertension/hypertension, 18,19 the metabolic syndrome, 38,39 hyperlipidemia, 18,40,41 coronary artery disease, 17,42 stroke/TIA/carotid artery disease, 21-23,29,43-45 arthritis, 46 and cancer 47 ).…”