Clinical Effects of Acupuncture for Diabetic Peripheral Neuropathy

Zhang, Cheng; Ma, Yaqi; Yan, Ye

doi:10.1016/s0254-6272(10)60003-9

Cited by 66 publications

(95 citation statements)

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“…The effectiveness rate expressed by this cohort of patients is similar to that of Zhang et al 12 and Abuaisha et al 10 who achieved success rates of 87.5% and 77%, respectively, in managing diabetic PN.…”

Section: Discussionsupporting

confidence: 86%

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Evaluation of Acupuncture in the Management of Chemotherapy-Induced Peripheral Neuropathy

2011

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Aim To clinically evaluate the effectiveness of acupuncture when used in the management of chemotherapy-induced peripheral neuropathy (PN). Background During cancer treatment, certain chemotherapies can cause varying degrees of PN. Patients' quality of life can be seriously impaired through loss of sensation, pain or mobility problems. Conventional medications routinely used to manage neuropathic symptoms have poor side-effect profi les and there is little or no evidence justifying their use to treat chemotherapy-related neurotoxicities. There are studies suggesting that acupuncture may be an effective therapy in treating PN across a number of different aetiologies. Design A retrospective service evaluation. Method Patients (n=18) were referred for acupuncture by the medical staff and/ or nurse specialists or they self-referred for treatment. A course of six weekly acupuncture sessions was offered to them, and their details were recorded on an evaluation form prior to session one. Points were selected by acupuncturists, based on patient presentation, and needles remained in situ for 30-45 min. Treatments took place in outpatient clinics, chemotherapy day case ward or a drop-in clinic based in a physiotherapy gym. The evaluation form was completed at the end of session 6 by a therapist who had not been involved in patient care.

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Section: Discussionsupporting

confidence: 86%

“…Pregabalin appears to be effective, but it is expensive and retains a poor side-effect profi le. In diabetic neuropathy, however, preliminary studies show some promise in using acupuncture as an adjunct to standard medication [10][11][12] and this may translate to chemotherapy induced PN. The exact mechanism of acupuncture remains unclear.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Acupuncture in the Management of Chemotherapy-Induced Peripheral Neuropathy

2011

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“…Very rare, sporadic, single cases of injury have been reported [15-17] and are usually due to negligence on the part of the practitioner rather than to the treatment itself. Although studies have shown that acupuncture may be helpful for managing neuropathic pain in patients with HIV/AIDS [18,19] and diabetes [20-24], few studies [25-28] have evaluated its use in chemotherapy-induced PN.…”

Section: Introductionmentioning

confidence: 99%

Electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: a feasibility study

et al. 2014

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BackgroundThis single-arm study evaluated feasibility, safety, and initial efficacy of electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy (PN) in cancer patients with multiple myeloma.MethodsPatients with neuropathy ≥ grade 2 received 20 acupuncture treatments over 9 weeks.ResultsFor the 19 evaluable patients, Functional Assessment of Cancer Therapy/Gynecological Oncology Group-Neurotoxicity (FACT/GOG/NTX) mean (SD) scores improved significantly between baseline and week 13 (20.8 [9.6] vs 13.2 [8.5], p = 0.0002). Moderate effect size differences began on week 4, with the largest effect size differences found at week 9 for FACT/GOG/NTX scores, worst pain in the last 24 hours, and pain severity (Cohen’s d = 1.43, 1.19, and 1.08, respectively) and continuing through week 13 (Cohen’s d = 0.86, 0.88, and 0.90, respectively). From baseline to week 13, additional significant improvements were seen as follows: postural stability (1.0 [0.6] vs 0.8 [0.4], p = 0.02); coin test (10.0 [7.4] vs 5.6 [1.9], p < 0.0001); button test (96.1 [144.4] vs 54.9 [47.3], p < 0.0001); and walking test (21.6 [10.0] vs 17.2 [7.7], p = 0.0003). No significant changes were seen with NCS.ConclusionsAcupuncture may help patients experiencing thalidomide- or bortezomib-induced PN. Larger, randomized, clinical trials are needed.Trial registrationClinicalTrials.gov Identifier: NCT00891618.

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“…They are included as potential therapeutic options in the recent AAN guidelines [49]. Acupuncture, but not traditional Chinese herbal medicine, seems to be slightly effective [79,80,81]. Transcutaneous electric nerve stimulation should also be considered in the treatment of painful diabetic neuropathy [82].…”

Section: Treatment Of Diabetic Neuropathymentioning

confidence: 99%

Diabetic Neuropathies: Diagnosis and Management

et al. 2013

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Introduction: Changes in human behaviour and lifestyle over the last century have resulted in a dramatic increase in the incidence of diabetes worldwide. Neuropathy is a common and costly complication of both type 1 and type 2 diabetes. The prevalence of neuropathy is estimated to be about 8% in newly diagnosed patients and greater than 50% in patients with long-standing disease. There are two main types of diabetic neuropathies, named as sensorimotor and autonomic neuropathies. Sensorimotor neuropathy is marked by pain, paraesthesia and sensory loss, and autonomic neuropathy may contribute to myocardial infarction, malignant arrhythmia and sudden death. Methods: In this article we reviewed the pathogenesis, clinical manifestations diagnosis and treatment of diabetic neuropathies. Conclusion: Sensorimotor and autonomic neuropathies (cardiovascular, gastrointestinal and genitourinary autonomic neuropathies) are common in diabetic patients. Apart from strict glycaemic control, no further therapeutic approach exists in the prevention of this phenomenon. Intensive diabetes therapy, intensive multifactorial cardiovascular risk reduction and lifestyle intervention are recommended in patients with cardiovascular autonomic neuropathy. Gastroparesis is the most debilitating complication of gastrointestinal autonomic neuropathy and genitourinary autonomic neuropathy can cause sexual dysfunction and neurogenic bladder; these conditions are hard to manage. The symptomatic treatment of sensory symptoms includes tricyclic antidepressants, serotonin and norepinephrine reuptake inhibitors, gabapentin, pregabalin and opioids. Other treatment strategies are not so effective.

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Clinical Effects of Acupuncture for Diabetic Peripheral Neuropathy

Cited by 66 publications

References 0 publications

Evaluation of Acupuncture in the Management of Chemotherapy-Induced Peripheral Neuropathy

Evaluation of Acupuncture in the Management of Chemotherapy-Induced Peripheral Neuropathy

Electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: a feasibility study

Diabetic Neuropathies: Diagnosis and Management

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