Clinical Efficacy of Carbon Dioxide Laser Combined with ALA Photodynamics in the Treatment of Condyloma Acuminatum

Cao, Chunyu; Chen, Lihua; Li, Shu; Yuan, Lili; Wang, Yishan

doi:10.1155/2021/7211055

Cited by 3 publications

(4 citation statements)

References 16 publications

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“…Recurrence refers to the occurrence of new warts within 2.0 cm of the original wart site or the original wart site within 6 months after the removal of wart body treatment [ 11 ]. The histopathological examination wart body is positive, and the history of repeated infection is excluded.…”

Section: Methodsmentioning

confidence: 99%

Establishing a prediction model for recurrence of condyloma acuminatum

et al. 2022

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We collected the clinical data of 156 patients diagnosed with condyloma acuminatum (CA), including age, gender, marriage, education level, stay up late, smoking, drinking, number of sexual partners, HPV infection status of sexual partners, genitourinary and anal diseases, condom use, other diseases of HPV infection, location and number of warts, HPV typing, etc. Analyze the risk factors affecting the recurrence of CA, explore the influencing factors and independent influencing factors of CA recurrence, establish the prediction model of CA recurrence, and evaluate its prediction value. Univariate analysis showed that stay up late, HPV infection status of sexual partners, urogenital diseases, condom use, other diseases of HPV infection and the number of CA were the influencing factors of CA recurrence. Multivariate analysis showed that condom use (OR = 0.166), HPV infection status of sexual partners (OR = 4.848), number of warts (OR = 1.212) and urogenital diseases (OR = 3.179) were independent factors affecting the recurrence of CA (P < 0.05). Therefore, the prediction model of CA recurrence can be established, and the area under the curve AUC of the prediction model was calculated to be 0.867 (95% CI 0.812–0.923). The model established in this study has certain prediction value for the recurrence of CA and can be used to preliminarily predict the recurrence of CA.

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Section: Methodsmentioning

confidence: 99%

Establishing a prediction model for recurrence of condyloma acuminatum

et al. 2022

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“…Tis article has been retracted by Hindawi following an investigation undertaken by the publisher [1]. Tis investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process:…”

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confidence: 99%

“…This article has been retracted by Hindawi following an investigation undertaken by the publisher [ 1 ]. This investigation has uncovered evidence of one or more of the following indicators of systematic manipulation of the publication process: Discrepancies in scope Discrepancies in the description of the research reported Discrepancies between the availability of data and the research described Inappropriate citations Incoherent, meaningless and/or irrelevant content included in the article Peer-review manipulation …”

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confidence: 99%

Retracted: Clinical Efficacy of Carbon Dioxide Laser Combined with ALA Photodynamics in the Treatment of Condyloma Acuminatum

Medicine¹

2023

Evidence-Based Complementary and Alternative Medicine

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“…ALA-PDT therapy is a popular therapy in recent years. In addition to treating genital warts, this method has a certain therapeutic effect on skin precancerous lesions, malignant tumors, acne and atrophic lichen sclerosis and it is not easy to cause drug resistance in the process of killing pathogenic microorganisms [11,12] . ALA-PDT therapy is mainly based on the principle that photosensitizers produce destructive substances under the irradiation of specific wavelengths of light.…”

mentioning

confidence: 99%

Effect of 5-Aminolevulinic Acid Photodynamic Therapy Combined with Carbon dioxide Laser on Condyloma Acuminatum

Xie¹,

Zhong²,

Tang³

et al. 2023

IJPS

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Effect and Prognosis of Condyloma AcuminatumBy comparing 5-aminolevulinic acid photodynamic therapy combined with carbon dioxide laser and carbon dioxide laser therapy only, to explore the therapeutic effect of 5-aminolevulinic acid photodynamic therapy combined with carbon dioxide laser on perianal and anal canal condyloma acuminatum. A total of 74 patients with perianal and anal canal condyloma acuminatum who were admitted to our hospital from January 2021 to December 2021 were selected as the research objects. They were randomly assigned to the observation group and the control group, with 37 cases in each group. The observation group was treated with 5-aminolevulinic acid photodynamic therapy combined with carbon dioxide laser and the control group was treated with carbon dioxide laser therapy. Both groups were treated once a week for 3 w. The therapeutic effect, recurrence rate and adverse reactions were compared between the two groups. The cure rate of condyloma acuminatum in the observation group was 86.48 %, which was higher than 54.05 % in the control group, with statistical significance (p<0.05). After follow-up, it was found that the recurrence rate of the observation group (13.51 %) was significantly lower than that of the control group (43.24 %), with statistical significance (p<0.05). The incidence of superficial scar and perianal pain in the observation group was 27.03 % and 21.62 % respectively, which was not significantly different from 35.14 % and 29.73 % in the control group. 5-aminolevulinic acid photodynamic therapy combined with carbon dioxide laser in the treatment of perianal and anal canal condyloma acuminatum has the advantages of good curative effect and low recurrence rate, which is worthy of clinical promotion.

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Clinical Efficacy of Carbon Dioxide Laser Combined with ALA Photodynamics in the Treatment of Condyloma Acuminatum

Cited by 3 publications

References 16 publications

Establishing a prediction model for recurrence of condyloma acuminatum

Establishing a prediction model for recurrence of condyloma acuminatum

Retracted: Clinical Efficacy of Carbon Dioxide Laser Combined with ALA Photodynamics in the Treatment of Condyloma Acuminatum

Effect of 5-Aminolevulinic Acid Photodynamic Therapy Combined with Carbon dioxide Laser on Condyloma Acuminatum

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