Clinical efficacy of chitosan‐based hydrocolloid dressing in the treatment of chronic refractory wounds

Liu, Jing; Shen, Hong

doi:10.1111/iwj.13801

Cited by 13 publications

(5 citation statements)

References 34 publications

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“…Our extensive literature search, which initially included 1135 articles, culminated in the careful selection of 8 studies 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 for this meta‐analysis. Table 1 provides a detailed overview of these studies, highlighting their key characteristics and methodologies, with a particular focus on the use of hydrocolloid dressings in the context of NIV and maxillofacial surgery.…”

Section: Resultsmentioning

confidence: 99%

Role of hydrocolloid dressing in preventing face pressure ulcers from non‐invasive ventilation and facilitating postoperative wound healing in maxillofacial surgery: A meta‐analysis

Wang,

Gao,

Feng

et al. 2024

International Wound Journal

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Facial pressure ulcers from non‐invasive ventilation (NIV) and challenges in wound healing post‐maxillofacial surgery are significant concerns in clinical care. This meta‐analysis aimed to evaluate the effectiveness of hydrocolloid dressings in these contexts. From a pool of 1135 articles, 8 studies met the inclusion criteria. Hydrocolloid dressings demonstrated a significant reduction in facial pressure ulcers for NIV patients, with lower REEDA scores 1‐week postapplication (standardized mean difference [SMD] = −16.7, 95% confidence interval [CI]: −24.26 to −9.15, p < 0.01). In maxillofacial surgery, patients treated with hydrocolloid dressings exhibited improved wound healing and reduced scar formation, evidenced by lower Manchester Scar Scale scores 3 months post‐surgery (SMD = −15.46, 95% CI: −20.28 to −10.64, p < 0.01). These findings suggest that hydrocolloid dressings are effective in both preventing NIV‐related facial pressure ulcers and enhancing wound healing in maxillofacial surgery.

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Section: Resultsmentioning

confidence: 99%

Role of hydrocolloid dressing in preventing face pressure ulcers from non‐invasive ventilation and facilitating postoperative wound healing in maxillofacial surgery: A meta‐analysis

Wang,

Gao,

Feng

et al. 2024

International Wound Journal

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“…23,24 Another report mentioned the use of ultrasound jelly to seal the wound when applying NPWT to the foot, 25 but this was not appropriate in these moisture-prone areas in this study. Hydrocolloid dressings have been widely used in a variety of acute and chronic wounds, such as pressure injuries and post-operative incisions, [26][27][28] and have also shown good results in the treatment of severe diaper dermatitis, 29 demonstrating their moisture-defying, tightly adherent, skin friendly, and comfortable properties. The combined application of hydrocolloid dressings and NPWT was described and analysed in detail for the first time in this study, extending the range of applications for hydrocolloid dressings.…”

Section: Discussionmentioning

confidence: 99%

Effect of hydrocolloid dressings on preventing air leakage when applying negative pressure wound therapy to the perineum, buttocks, and sacrococcygeal region

Wang,

Li,

et al. 2024

Wound Repair Regeneration

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Maintaining a vacuum when applying NPWT is the key to its function, which is a challenge in the perineum, buttocks, and sacrococcygeal region. A retrospective cohort study was conducted to assess the effect of hydrocolloid dressings on preventing air leakage when applying NPWT in these regions. There were 61 patients in Group A (without the aid of hydrocolloid dressings) and 65 patients in Group B (with the aid of hydrocolloid dressings). The hydrocolloid dressing‐assisted NPWT significantly reduced the incidence of air leakage compared with conventional NPWT placement (24.6% vs 7.7%; risk ratio 3.20, 95% confidence interval 1.24 to 8.27; P = 0.009), while decreasing the number of open NPWT applications (2.2 vs 1.7; difference, 0.43; 95% confidence interval, 0.19 to 0.66; P < 0.001), shortening hospital stays (20.1 vs 16.1; difference, 4.07; 95% confidence interval, 1.68 to 6.46; P = 0.01), and reducing the incidence of adverse skin events (18.0% vs 4.6%; risk ratio 3.91, 95% confidence interval 1.14 to 13.34; P = 0.017). These findings support the routine use of hydrocolloid dressing‐assisted NPWT placement in the perineum, buttocks, and sacrococcygeal region.This article is protected by copyright. All rights reserved.

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“… 55 A retrospective study showed a significant improvement in wound healing, degree of pain, and wound itchiness in 80 patients with chronic refractory wounds treated with CS‐based hydrocolloid dressing for 3 weeks. 56 CS shortens the inflammatory phase by facilitating the migration of macrophages and other active cells to clear the inflammatory mediators and cellular debris at the wound site, improving wound healing. 57 CS‐based oligosaccharides significantly reduce lipopolysaccharide‐induced release of proinflammatory cytokines such as IL‐1β, IL‐6, and TNF‐α from the THP‐1 monocytes, indicating the anti‐inflammatory potential of CS.…”

Section: The Need To Incorporate Other Polymers Into the Honey Hydrogelmentioning

confidence: 99%

“…CS's hemostatic nature was demonstrated by the shortened hemostasis time in rat models compared to conventional gauze dressing 55 . A retrospective study showed a significant improvement in wound healing, degree of pain, and wound itchiness in 80 patients with chronic refractory wounds treated with CS‐based hydrocolloid dressing for 3 weeks 56 . CS shortens the inflammatory phase by facilitating the migration of macrophages and other active cells to clear the inflammatory mediators and cellular debris at the wound site, improving wound healing 57 .…”

Section: The Need To Incorporate Other Polymers Into the Honey Hydrogelmentioning

confidence: 99%

Incorporation of natural and synthetic polymers into honey hydrogel for wound healing: A review

Chin,

Azman,

Tan

2024

Health Science Reports

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Background and AimsThe difficulty in treating chronic wounds due to the prolonged inflammation stage has affected a staggering 6.5 million people, accompanied by 25 billion USD annually in the United States alone. A 1.9% rise in chronic wound prevalence among Medicare beneficiaries was reported from 2014 to 2019. Besides, the global wound care market values were anticipated to increase from USD 20.18 billion in 2022 to USD 30.52 billion in 2030, suggesting an expected rise in chronic wounds financial burdens. The lack of feasibility in using traditional dry wound dressings sparks hydrogel development as an alternative approach to tackling chronic wounds. Since ancient times, honey has been used to treat wounds, including burns, and ongoing studies have also demonstrated its wound‐healing capabilities on cellular and animal models. However, the fluidity and low mechanical strength in honey hydrogel necessitate the incorporation of other polymers. Therefore, this review aims to unravel the characteristics and feasibility of natural (chitosan and gelatin) and synthetic (polyvinyl alcohol and polyethylene glycol) polymers to be incorporated in the honey hydrogel.MethodsRelevant articles were identified from databases (PubMed, Google Scholar, and Science Direct) using keywords related to honey, hydrogel, and polymers. Relevant data from selected studies were synthesized narratively and reported following a structured narrative format.ResultsThe importance of honey's roles and mechanisms of action in wound dressings were discussed. Notable studies concerning honey hydrogels with diverse polymers were also included in this article to provide a better perspective on fabricating customized hydrogel wound dressings for various types of wounds in the future.ConclusionHoney's incapability to stand alone in hydrogel requires the incorporation of natural and synthetic polymers into the hydrogel. With this review, it is hoped that the fabrication and commercialization of the desired honey composite hydrogel for wound treatment could be brought forth.

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Clinical efficacy of chitosan‐based hydrocolloid dressing in the treatment of chronic refractory wounds

Cited by 13 publications

References 34 publications

Role of hydrocolloid dressing in preventing face pressure ulcers from non‐invasive ventilation and facilitating postoperative wound healing in maxillofacial surgery: A meta‐analysis

Role of hydrocolloid dressing in preventing face pressure ulcers from non‐invasive ventilation and facilitating postoperative wound healing in maxillofacial surgery: A meta‐analysis

Effect of hydrocolloid dressings on preventing air leakage when applying negative pressure wound therapy to the perineum, buttocks, and sacrococcygeal region

Incorporation of natural and synthetic polymers into honey hydrogel for wound healing: A review

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