Clinical Efficacy of Giomer Versus Sodium Fluoride Varnish for Management of Hypersensitivity: Randomized Control Trail

Abstract

Aim: to assess the clinical effectiveness of Giomer varnish in comparison to sodium fluoride in reducing dentin hypersensitivity. Methodology: Using a Split mouth design, 66 participants (132 teeth) of the outpatient clinic in the Faculty of dentistry, Cairo University, were enrolled. Each participant should have at least two sensitive teeth in different sides of the same jaw, with a visual analogue scale score two or more. Teeth were examined by using different stimuli: Evaporative, thermal and tactile stimuli. Sides were categorized randomly into two groups according to the desensitizing agents used either sodium fluoride or Giomer varnish. Degree of Hypersensitivity was assessed by visual analogue scale (VAS) before the application of the agents T 1 , immediately after T 2 , 1 week T 3 and one month later T 4. Data were analyzed using Two way ANOVA, partial eta-squared, Kruskal-Wallis, Bonferronicorrected Wilcoxon, Mann-Whitney test and Chi-square tests. Absolute risk, relative risk, relative risk reduction with 95% confidence interval of dentin hypersensitivity were calculated. Results: Sodium fluoride exhibited high VAS scale at T 1 3.39(1.11), T 2 3.21(0.99) and T 4 3.13(1.01) with a non-statistical difference between them. While at T 3 statistically lower VAS scale 1.30 (0.9) was shown in this group. Giomer exhibited high VAS scale at T 1 3.79(1.5) followed by T 2 2.17(0.57) and T 4 2.56(1.87) with a non-statistical difference between them. While at T 3 lower VAS scale 0.17(0.57) was shown in this group. Influence of different assessment times within each agent was statistically significant at P <0.0001. At T2 and T3, Giomer revealed statistically lower VAS scale and it exhibited a relative risk reduction by 83% at T 3 and 24% at T 4. Conclusion: Giomer varnish is a promising desensitizing agent, which can replace sodium fluoride varnish in management of dentin hypersensitivity.

Single-session associative protocol for dentin hypersensitivity management: a 1-year randomized, blinded clinical study

“…Similar results were found in a clinical study comparing PBC and BiFluorid 10 for reducing DH, where PBC showed a significant difference only in the evaluation conducted 1 week after application [ 37 ]. The fact that the reduction in DH does not occur immediately after the application of PBC may be related to its mechanism of action, which occurs gradually when in contact with oral fluids, by binding ions to collagen fibers, while fluoride and strontium bind to apatite present in the dental structure, improving its resistance to acid attack [ 22 ].…”

“…The results obtained in this study were significant for the management of DH at all proposed time points, and they particularly stood out in the PDR and control groups. It should be mentioned that PBC is a promising agent that has demonstrated its long-lasting effect in managing DH due to its mechanism of ion release and precipitation, aiding in remineralization and obliteration of dentinal tubules, as observed after 12 months of application in this study, as well as in the Control group [ 37 ]. This is attributed to the characteristics of SBU, with the presence of 10-MDP, which stabilizes in an aqueous medium and chemically bonds with dentin, obliterating the dentinal tubules [ 32 ].…”

Alterations in Surface Gloss and Hardness of Direct Dental Resin Composites and Indirect CAD/CAM Composite Block after Single Application of Bifluorid 10 Varnish: An In Vitro Study

“…Most fluoride 2 of 11 varnishes comprise 5% sodium fluoride; nevertheless, the manufacturer may have various fluoride concentrations and forms [5]. Sodium fluoride varnish is regarded as the gold standard desensitizing substance [6]. Bifluorid 10 (5% sodium fluoride and 5% calcium fluoride) adheres to the teeth and begins to provide instant protection from any damaging stimulus [7].…”