Clinical Efficacy of Immunotherapy in Allergic Rhinitis

Abstract

Patients treated with SCIT are at risk of both local and systemic adverse reactions; however, in most cases, symptoms are readily reversible if they are recognized early and treated promptly. The safety profile of SLIT is good; therefore, SLIT can be self-administered by patients in their homes. In this article, we reviewed the efficacy and safety of allergen immunotherapy.

Effects of a Cloth Panel Containing a Specific Ore Powder on Patients with Japanese Cedar Pollen Allergy During the Pollen Dispersal Season

“…Additionally, some patients with pollen allergies can have adverse reactions to as many as 50 types of plants including cypress, rice, ragweed, and mugwort. The treatment of pollen allergy is generally limited to suppressing symptoms, with oral antihistamines, nasal drops, or eye drops typically being used as therapeutic strategies [7][8][9]. Although desensitization therapy has been tried [9][10][11], it has not been fully effective, and patients just wait for the pollen season to pass.…”

“…The treatment of pollen allergy is generally limited to suppressing symptoms, with oral antihistamines, nasal drops, or eye drops typically being used as therapeutic strategies [7][8][9]. Although desensitization therapy has been tried [9][10][11], it has not been fully effective, and patients just wait for the pollen season to pass. Precautions can be taken to avoid or minimize exposure to pollen through decreasing outdoor activities, closing windows, operating central air conditioning systems with filter attachments, bathing and shampooing the body and hair well to remove attached pollens, and drying clothes well.…”

Safety and monitoring of allergen immunotherapy

“…Nie ma danych porównujących bezpieczeństwo AIT w ANN wywoływanym przez różne pyłki (np. : pyłek drzew vs pyłek traw) oraz AIT u chorych na ANN pyłkowy w porównaniu z ANN związanym z alergenami całorocznymi (roztocza) [16].…”

Is house dust mite spesific sublingual immunotherapy successful in termination of inhaled corticosteroid treatment in children with asthma?

“…Allergen-specific sublingual immunotherapy (SLIT) establishes modification in the underlying immunologic mechanisms of the disease in addition to eradication of symptoms (1) . Sublingual immunotherapy was proven to be feasible, safe and effective in allergic respiratory disorders of adults and children (2)(3)(4)(5)(6) . Decline in both the occurence of new sensitizations and allergic symptoms in children was proven (7,8) .…”