The journal invites readers to submit short, well-focused questions about specific topics that trouble them in their practice. The questions should be typed double-spaced and must not be longer than one-half page. The author's name and address should be included, but these will not be published if so requested. Questions will be answered by consultants selected by the Editor. All questions are subject to editing and will be published as space permits. Answers supplied by radiologist consultants should not be considered inclusive of all approaches to a problem or exclusive of other methods of obtaining the same result. Consultants' recommendations on any specific radiologic procedure or course of conduct should be considered in light of the circumstances presented by an individual patient's situation.
AnswerBreast cancer is a leading cause of cancer death in women older than 65 years. Both the incidence and mortality rates increase as a function of age. In the United States, approximately 45% of new breast cancers occur in women older than 65 years [1]. Although women over 65 account for only 13% of the adult population, an explosive growth of the aged is anticipated because of improvements in health care and the aging of baby boomers. By the year 2030, 20% of the population is expected to be older than 65 years [2].Of the many misconceptions of the elderly, one of the most common is an underestimation of life expectancy. A woman who lives to age 65 can be expected to live an additional 18 years (age at death, 83 years). A 75-year-old woman can be expected to live 12 more years, and an 85-year-old woman, 7 more years [3].Elderly patients present with breast cancer typically at a later stage than younger women in part because of the underutilization of physical examination and mammography. Treatment choices are more limited because of later detection. Survival is adversely affected even when cancer is diag-nosed in women older than 75. Stage at the time of diagnosis remains the most important determinant of survival in the elderly from breast cancer [4].Unfortunately, randomized controlled screening trials have not included sufficient numbers of women older than 69 years to provide a definitive answer regarding screening the elderly. We are left with inferential evidence based on case control studies and computer-modeling to make a rational decision regarding screening elderly patients. Because tumor size and stage have been shown to correlate with survival, several studies have assessed these parameters in elderly women who have undergone screening. In both women ranging in age from 65 to 75 years and women older than 75 years, smaller and lower stage tumors have been detected in screened women than nonscreened women [5]. Additionally, tumor size and stage in screened women over 65 are similar to tumor size and stage in screened women ranging in the 50-65 age group, a group known to benefit from screening mammography [3]. These lines of evidence support screening. Women screened annually have smaller tumors and lo...