Clinical Efficacy of Noninvasive Cryolipolysis and Its Effects on Peripheral Nerves

Coleman, Sydney R.; Sachdeva, Kulveen; Egbert, Barbara M.; Preciado, Jessica; Allison, John G.

doi:10.1007/s00266-008-9286-8

Cited by 153 publications

(156 citation statements)

References 12 publications

Supporting

Mentioning

142

Contrasting

Unclassified

Order By: Relevance

“…Only one treatment was usually necessary but diminishing returns with additional treatments were reported 18 and onset took about 8 weeks 11,44 . In addition to the abdomen 10,18,[45][46] , flank 10-11, 18, 44-48 , buttocks 45 and back 10,[45][46] , specific applicators exist for the arms 50 , knees 10,45 and thighs 10,[45][46][49][50][51][52] .…”

Section: Cryomentioning

confidence: 99%

See 1 more Smart Citation

Noninvasive Body Contouring: Literature Review and Summary of Objective Data

Bernstein

Farberg²,

Khorasani³

et al. 2017

J of Skin

View full text Add to dashboard Cite

Capsule Summary:• Noninvasive body contouring devices vary by efficacy, treatment schedule and safety profile.• This review compares body contouring modalities, allowing for quick comparison between modalities.• This review enables the selection of a body contouring modality that best suits each specific patient's goals, availability and aversion to risk. Background: There is increasing demand for noninvasive body contouring but objective data is difficult to compare between modalities. Currently, the most accepted forms of noninvasive body contouring are cryolipolyisis (Cryo), focused ultrasound (FUS), radiofrequency (RF), and low level laser therapy (LLLT). AbbreviationsObjective: To summarize the objective data on noninvasive body contouring. Methods:In October 2016, a pubmed search was performed with terms "noninvasive body contouring" or "non-invasive body contouring." The search was limited to human studies in English on the four major modalities.Results: 55 articles yielded data from 3649 patients. The most well studied modality was Cryo and the least was RF. Decreased abdominal/flank localized adiposity was most the most common endpoint reported. Both the minimum and maximum reported decreases in abdominal girth were from studies using RF (1.4cm and 7.4cm, respectively). Side effects were most common and significant with Cryo and absent with LLLT. Conclusions:Noninvasive body contouring has a significant amount of objective data available in the literature to date. Reductions of localized adiposity are clinically and statistically significant but modest. To date, the best reported positive results have been obtained with RF and the lowest risk of side effects is with LLLT. ABSTRACT SKINJuly 2017 Volume I Issue I

show abstract

Section: Cryomentioning

confidence: 99%

“…Cryo did not report results using girth as a metric but reported 19.6-25.5% decreased abdominal/flank fat thickness when measured by ultrasound [10][11] . One RF study reported 29% decreased abdominal/flank fat thickness by ultrasound 8 .…”

mentioning

confidence: 99%

Noninvasive Body Contouring: Literature Review and Summary of Objective Data

Bernstein

Farberg²,

Khorasani³

et al. 2017

J of Skin

View full text Add to dashboard Cite

show abstract

“…Numerous clinical studies have examined cryolipolysis and its mechanisms (7,8). To our knowledge, however, no article has reported the simulation of cryolipolysis.…”

Section: Introductionmentioning

confidence: 99%

“…Their findings indicated that cryolipolysis leads to a transient reduction in sensory function in 67% of subjects. However, these changes in sensory nerves were resolved within 1-6 weeks following heat extraction and none of the subjects suffered any permanent deficiencies (7).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Simulation of cryolipolysis as a novel method for noninvasive fat layer reduction

Majdabadi¹,

Abazari²

2016

Turk J Med Sci

View full text Add to dashboard Cite

Background/aim: Regarding previous problems in conventional liposuction methods, the need for development of new fat removal operations was appreciated. In this study we are going to simulate one of the novel methods, cryolipolysis, aimed to tackle those drawbacks. Materials and methods:We think that simulation of clinical procedures contributes considerably in efficacious performance of the operations. To do this we have attempted to simulate temperature distribution in a sample fat of the human body. Using Abaqus software we have presented the graphical display of temperature-time variations within the medium.Results: Findings of our simulation indicate that tissue temperature decreases after cold exposure of about 30 min. It can be seen that the minimum temperature of tissue occurs in shallow layers of the sample and the temperature in deeper layers of the sample remains nearly unchanged. It is clear that cold exposure time of more than the specific time (t > 30 min) does not result in considerable changes. Conclusion:Numerous clinical studies have proved the efficacy of cryolipolysis. This noninvasive technique has eliminated some of drawbacks of conventional methods. Findings of our simulation clearly prove the efficiency of this method, especially for superficial fat layers.

show abstract

Paradoxical Adipose Hyperplasia After Cryolipolysis

et al. 2014

View full text Add to dashboard Cite

Importance Cryolipolysis is the non-invasive reduction of fat with localized cutaneous cooling. Since initial introduction, over 650,000 cryolipolysis treatment cycles have been performed worldwide. We present a previously unreported, rare side effect following cryolipolysis, paradoxical adipose hyperplasia. Observations A 41-year-old man underwent a single cycle of cryolipolysis to his abdomen. Three months following his treatment, a gradual enlargement of the treatment area was noted. This enlargement was a large, well-demarcated subcutaneous mass, slightly tender to palpation. Imaging studies revealed accumulation of adipose tissue with normal signal intensity within the treatment area. Conclusions and Relevance Paradoxical adipose hyperplasia is a rare, previously unreported side effect of cryolipolysis with an incidence of 0.0051%. No single unifying risk factor has been identified. The phenomenon seems to be more common in male patients undergoing cryolipolysis. At this time there is no evidence of spontaneous resolution. Further studies are needed to characterize the pathogenesis and histologic findings of this rare adverse event.

show abstract

Clinical Efficacy of Noninvasive Cryolipolysis and Its Effects on Peripheral Nerves

Abstract: Noninvasive cryolipolysis results in substantial fat reduction within 2 months of treatment without damage to skin. The procedure is associated with modest reversible short-term changes in the function of peripheral sensory nerves.

Cited by 153 publications

References 12 publications

Noninvasive Body Contouring: Literature Review and Summary of Objective Data

Noninvasive Body Contouring: Literature Review and Summary of Objective Data

Simulation of cryolipolysis as a novel method for noninvasive fat layer reduction

Paradoxical Adipose Hyperplasia After Cryolipolysis

Contact Info

Product

Resources

About