Clinical evaluation of 3 Mix and Other Mix in non-instrumental endodontic treatment of necrosed primary teeth

Abstract

a b s t r a c tProblem considered: The objective was to evaluate and compare the clinical and radiographic efficacy of two different combinations of antibacterial drugs when used in noninstrumental endodontic treatment of necrosed primary teeth.Materials and method: Forty teeth were randomly divided into two groups, viz. groups A and B having 20 teeth each. In Group A, 3 Mix (ciprofloxacin, metronidazole, and minocycline) and in Group B, Other Mix (ciprofloxacin, ornidazole, and minocycline) mixed with propylene glycol were used. Medication cavities of Group-A and B were filled with 3 Mix and Other Mix respectively followed by restoration of teeth. Clinical evaluation was done at 3 months whereas, clinical and radiographic evaluation was done at 6 and 12 months, respectively.Results: Both the groups showed 100% clinical success whereas, radiographic success rate was 81% with 3 Mix and 92% with Other Mix but, was not statistically significant.Conclusions: Both the antibacterial pastes can be used effectively in non instrumental endodontic treatment of necrosed primary teeth and require more clinical trials to prove its efficacy.

Clinical and Radiographic Evaluation of 3Mix and Vitapex as Pulpectomy Medicament in Primary Molars: An In Vivo Study

“…Cruz et al found that propylene glycol delivered dye through the root canal system rapidly and more effectively indicating its potential use in delivering intracanal medicament. 11 In the study conducted by Takushige et al, 9 Prabhakar et al, 8 Nanda et al, 12 and Pinky et al, 7 medication cavity was prepared prior to the placement of 3Mix in which the orifice were enlarged with straight bur to receive the medicament. However, medication cavity was not prepared in the present study.…”

Clinical and Radiographic Evaluation of Chloramphenicol-Tetracycline-Zinc Eugenol Oxide Antibiotic Paste in Pulp Treatment

“…However, it has been reported that when a systemic antibiotic is administered, only a small part of the drug concentration reaches the root canal, which makes it of little benefit. In view of the above, the application of local antibiotics allows to administer substantially higher concentrations and to avoid systemic complications (Nanda et al 2014). This evidence has allowed for several years in the Pediatric Dentistry Specialty Clinic from the Autonomous University of Zacatecas to establish a non-instrumented endodontic treatment in primary teeth by using an antibiotic paste containing the antibacterial drug mixture for the treatment of dental organs with pulp involvement and doubtful prognosis.…”

Clinical and Radiographic Evaluation of CTZ (Chloramphenicol-Tetracycline-Zinc Eugenol Oxide) Antibiotic Paste in Pulp Treatment of Primary Molars

“…In view of the above, the application of local antibiotics allows to administer substantially higher concentrations and to avoid systemic complications. 25 This evidence has allowed for several years in the Pediatric Dentistry Specialty Clinic from the Autonomous University of Zacatecas to establish a non-instrumented endodontic treatment in primary teeth by using an antibiotic paste containing the antibacterial drug mixture for the treatment of dental organs with pulp involvement and doubtful prognosis. This biological approach is considered innovative because mechanical instrumentation is not required, which avoids further root canal expansion, unnecessary irritation on periapical tissues, decreasing operative times (performed in a single appointment), and can be applied satisfactorily in young children during early childhood.…”