Clinical Evaluation of a Mobile Digital Specimen Radiography System for Intraoperative Specimen Verification

Wang, Yingbing; Ebuoma, Lilian O.; Saksena, Mansi; Liu, Bob; Specht, Michelle C.; Rafferty, Elizabeth A.

doi:10.2214/ajr.13.11408

Cited by 11 publications

(6 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Kaufman et al 3 reported DSR and IDSM to be equally accurate in relation to identification of the target lesion by either surgeon or radiologist. IDSM has been shown to be more accurate for invasive than in situ disease, 6 to identify the index lesion, in 97% of patients 7 and to be reliable in identifying clear margins. 8 We identified 100% of lesions on specimen radiographs.…”

Section: Discussionmentioning

confidence: 99%

Comparison of the time taken for localised breast surgery pre‐ and post‐introduction of intra‐operative digital specimen mammography

Nascimento

Bourke

2017

J Med Imag Rad Onc

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Comparison of the time taken for localised breast surgery pre‐ and post‐introduction of intra‐operative digital specimen mammography

Nascimento

Bourke

2017

J Med Imag Rad Onc

View full text Add to dashboard Cite

show abstract

“…This shortens the duration of anaesthesia, reducing morbidity and mortality, and decreases operating room occupancy, thus reducing costs, while still providing comparable results to digital mammography. [14][15][16] The aim of this study was to directly compare the diagnostic performance of full-field digital mammography (FFDM), digital breast tomosynthesis and a dedicated digital specimen radiography system (SRS) for the evaluation of resected breast lesions in consecutive patients, and to compare the margin status of resected lesions versus the final pathological report.…”

Section: Introductionmentioning

confidence: 99%

Diagnostic performance of tomosynthesis, digital mammography and a dedicated digital specimen radiography system versus pathological assessment of excised breast lesions

Almasarweh

Sudah

Okuma

et al. 2022

Radiology and Oncology

View full text Add to dashboard Cite

Background The aim of the study was to compare the performance of full-field digital mammography (FFDM), digital breast tomosynthesis and a dedicated digital specimen radiography system (SRS) in consecutive patients, and to compare the margin status of resected lesions versus pathological assessment. Patients and methods Resected tissue specimens from consecutive patients who underwent intraoperative breast specimen assessment following wide local excision or oncoplastic breast conservative surgery were examined by FFDM, tomosynthesis and SRS. Two independent observers retrospectively evaluated the visibility of lesions, size, margins, spiculations, calcifications and diagnostic certainty, and chose the best performing method in a blinded manner. Results We evaluated 216 specimens from 204 patients. All target malignant lesions were removed with no tumouron-ink. One papilloma had positive microscopic margins and one patient underwent reoperation owing to extensive in situ components. There were no significant differences in measured lesion size among the three methods. However, tomosynthesis was the most accurate modality when compared with the final pathological report. Both observers reported that tomosynthesis had significantly better lesion visibility than SRS and FFDM, which translated into a significantly greater diagnostic certainty. Tomosynthesis was superior to the other two methods in identifying spiculations and calcifications. Both observers reported that tomosynthesis was the best performing method in 76.9% of cases. The interobserver reproducibilities of lesion visibility and diagnostic certainty were high for all three methods. Conclusions Tomosynthesis was superior to SRS and FFDM for detecting and evaluating the target lesions, spiculations and calcifications, and was therefore more reliable for assessing complete excision of breast lesions.

show abstract

“…8,9 To save time during surgery, the use of portable intraoperative X-ray systems to take images of the removed tissue inside the operating room is becoming popular. [8][9][10][11] These X-ray systems are based on a filament, the cathode, which is heated to emit electrons by thermionic emission. The emitted electron beam is targeted to a reflection-type metal, the anode, which generates an Xray beam in the direction perpendicular to the direction of the electron beam.…”

Section: Introductionmentioning

confidence: 99%

A feasibility study of a portable intraoperative specimen imaging X‐ray system based on carbon nanotube field emitters

Gupta

Yeo²,

Mativenga

et al. 2021

Int J Imaging Syst Tech

View full text Add to dashboard Cite

When breast cancer is surgically removed, a rim of normal tissue surrounding the tumor is also removed. This rim of normal tissue is called a margin and is studied by a pathologist to determine whether or not all tumor was removed. The pathologist achieves this by cutting the surgically removed tissue into thin slices and observing each slice under a microscope. This process is time-consuming. Here, we investigate the feasibility of using a portable carbon nanotube (CNT)-based X-ray system for in situ detection of the presence of tumor cells in the surgical margin. Using the proposed technique, we successfully obtain X-ray images, which clearly show cancer masses and microcalcifications. This feasibility study shows that portable CNT-based X-ray systems are promising candidates for next-generation in situ pathological examinations.

show abstract

Clinical Evaluation of a Mobile Digital Specimen Radiography System for Intraoperative Specimen Verification

Cited by 11 publications

References 13 publications

Comparison of the time taken for localised breast surgery pre‐ and post‐introduction of intra‐operative digital specimen mammography

Comparison of the time taken for localised breast surgery pre‐ and post‐introduction of intra‐operative digital specimen mammography

Diagnostic performance of tomosynthesis, digital mammography and a dedicated digital specimen radiography system versus pathological assessment of excised breast lesions

A feasibility study of a portable intraoperative specimen imaging X‐ray system based on carbon nanotube field emitters

Contact Info

Product

Resources

About