Clinical Evaluation of an Instrument-Integrated OCT-Based Distance Sensor for Robotic Vitreoretinal Surgery

Cereda, Matteo Giuseppe; Parrulli, Salvatore; Douven, Yanick; Faridpooya, Koorosh; Romunde, Saskia H M van; Hüttmann, Gereon; Eixmann, Tim; Schulz‐Hildebrandt, Hinnerk; Kronreif, Gernot; Beelen, Maarten; Smet, Marc D. de

doi:10.1016/j.xops.2021.100085

Cited by 13 publications

(7 citation statements)

References 19 publications

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“…It is the standby functionality the ability to suspend any task carried out by a robotic system that allows such fine measurements and provides the surgeon with the ability to carry out these precision task, uninhibited by time constraints. This independence means that the advancement of the needle through the retina can be planned once inside the eye in real time using existing iOCT machines, and because there is little motion of the eye, the signal to noise compensation algorithms are fully functional which allow for a fully optimized image of various retinal planes ( 72 ).…”

Section: Robotic Assistance For Subretinal Deliverymentioning

confidence: 99%

Subretinal Therapy: Technological Solutions to Surgical and Immunological Challenges

et al. 2022

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Recent advances in ocular gene and cellular therapy rely on precisely controlled subretinal delivery. Due to its inherent limitations, manual delivery can lead to iatrogenic damage to the retina, the retinal pigment epithelium, favor reflux into the vitreous cavity. In addition, it suffers from lack of standardization, variability in delivery and the need to maintain proficiency. With or without surgical damage, an eye challenged with an exogenous viral vector or transplanted cells will illicit an immune response. Understanding how such a response manifests itself and to what extent immune privilege protects the eye from a reaction can help in anticipating short- and long-term consequences. Avoidance of spillover from areas of immune privilege to areas which either lack or have less protection should be part of any mitigation strategy. In that regard, robotic technology can provide reproducible, standardized delivery which is not dependent on speed of injection. The advantages of microprecision medical robotic technology for precise targeted deliveries are discussed.

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Section: Robotic Assistance For Subretinal Deliverymentioning

confidence: 99%

Subretinal Therapy: Technological Solutions to Surgical and Immunological Challenges

et al. 2022

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“…It allows surgeons to use standard microscopes, such as M822 F40 Leica (Diegem, Belgium) [260], Zeiss Rescan 700 (Oberkochen, Germany) [262], or other visualization techniques like intraoperative OCT (Zeiss Resight 7000, Oberkochen, Germany). This integration offers valuable real-time imaging and enhanced visualization feedback to the surgeon during the procedure [263,265]. Moreover, when combined with the Eyesi surgical simulator, the PSS facilitates surgeons' quick acquisition of basic competency, enabling skill development and assessment [189,213,267,268].…”

Section: Preceyes Surgical Systemmentioning

confidence: 99%

Microsurgery Robots: Applications, Design, and Development

Wang,

Li,

et al. 2023

Sensors

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Microsurgical techniques have been widely utilized in various surgical specialties, such as ophthalmology, neurosurgery, and otolaryngology, which require intricate and precise surgical tool manipulation on a small scale. In microsurgery, operations on delicate vessels or tissues require high standards in surgeons’ skills. This exceptionally high requirement in skills leads to a steep learning curve and lengthy training before the surgeons can perform microsurgical procedures with quality outcomes. The microsurgery robot (MSR), which can improve surgeons’ operation skills through various functions, has received extensive research attention in the past three decades. There have been many review papers summarizing the research on MSR for specific surgical specialties. However, an in-depth review of the relevant technologies used in MSR systems is limited in the literature. This review details the technical challenges in microsurgery, and systematically summarizes the key technologies in MSR with a developmental perspective from the basic structural mechanism design, to the perception and human–machine interaction methods, and further to the ability in achieving a certain level of autonomy. By presenting and comparing the methods and technologies in this cutting-edge research, this paper aims to provide readers with a comprehensive understanding of the current state of MSR research and identify potential directions for future development in MSR.

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“…We wonder if our multiprobe might be also integrated with an optical coherence tomography-distance sensor to the tip of the probe, that has been already evaluated clinically in a robot-assisted setting. 6 How can we imagine robot-assisted surgery without mechanized automatic multiprobes?…”

Section: Dear Editormentioning

confidence: 99%