Clinical Evaluation of Highly Accelerated Compressed Sensing Time-of-Flight MR Angiography for Intracranial Arterial Stenosis

Lu, Shan-Shan; Qi, Mei; Zhang, X.; Mu, Xi Hu; Schmidt, Michaela; Sun, Yi; Forman, Christoph; Speier, Peter; Hong, Xiangfei

doi:10.3174/ajnr.a5786

Cited by 28 publications

(30 citation statements)

References 25 publications

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“…14 Different techniques to accelerate TOF-MRA have evolved over the recent years, one of which is compressed sensing, an undersampling algorithm of the k-space that is increasingly used in various MRI applications. [15][16][17][18][19][20][21] Spiral imaging is another method that has recently been introduced to clinical imaging applications. TOF-MRA using spiral imaging, as employed in this study, utilizes a stack of spirals with an in-plane spiral-out trajectory that has the advantage of short echo times (TEs) and an intrinsic compensation for higher gradient moments.…”

Section: Introductionmentioning

confidence: 99%

Novel Ultrafast Spiral Head MR Angiography Compared to Standard MR and CT Angiography

Greve

Sollmann

Höck³

et al. 2020

Journal of Neuroimaging

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Intracranial vessel imaging by time-of-flight MR angiography (TOF-MRA) is one of the most frequently performed investigations in clinical neuroradiology. Particularly in the acute setting, fast imaging is needed for diagnostics, with a sequence ideally depicting even small vessels. The purpose of this study was to compare image and diagnostic quality of a novel ultrashort TOF-MRA sequence accelerated by spiral imaging (TOF-Spiral-short) to a standard TOF-MRA sequence accelerated by compressed sensing (TOF-CS) and to CT angiography (CTA). METHODS: Forty-one patients (36.6% showing vessel pathologies) who had undergone TOF-CS (acquisition duration: 4 minutes 8 seconds), TOF-Spiral-short (acquisition duration: 51 seconds; spiral imaging [accelerating factor 1.3], decreased field of view [accelerating factor 1.2], and increased voxel size [accelerating factor 3.3]), and CTA were retrospectively evaluated. Assessment of image quality, diagnostic confidence, and quantification of stenosis or aneurysm diameter were performed by two readers. RESULTS: Image quality at the skull base was slightly reduced with TOF-Spiral-short compared to CTA and TOF-CS (P < .05). Delineation of small intracranial vessels was improved by TOF-Spiral-short compared to CTA (P < .0001). In TOF-Spiral-short, diagnostic confidence was not reduced compared to TOF-CS in patients with vessel pathologies. We observed no significant difference in quantitative pathology assessment between TOF-Spiral-short and the other two modalities. TOF-Spiral-short enabled the correct identification of all vessel pathologies. CONCLUSIONS: Accelerating TOF-MRA of brain-feeding arteries by a novel ultrashort spiral imaging sequence shows adequate image quality and sufficient diagnostic performance. Thus, TOF-Spiral-short holds potential for fast and reliable diagnostics of vessel pathologies, particularly in the acute setting.

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Section: Introductionmentioning

confidence: 99%

Novel Ultrafast Spiral Head MR Angiography Compared to Standard MR and CT Angiography

Greve

Sollmann

Höck³

et al. 2020

Journal of Neuroimaging

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“…CS-TOF-MRA has been successfully applied to the evaluation of different kinds of vascular pathologies, including intracranial aneurysm [33], moyamoya disease [31], and arterial stenosis [35][36][37]. However, to the best of our knowledge, the utility of CS-TOF-MRA in the evaluation of AVS has not been well investigated.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of cerebral arteriovenous shunts: a comparison of parallel imaging time-of-flight magnetic resonance angiography (TOF-MRA) and compressed sensing TOF-MRA to digital subtraction angiography

et al. 2020

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Purpose Time-of-flight (TOF)-MR angiography (MRA) is an important imaging sequence for the surveillance and analysis of cerebral arteriovenous shunt (AVS), including arteriovenous malformation (AVM) and arteriovenous fistula (AVF). However, this technique has the disadvantage of a relatively long scan time. The aim of this study was to compare diagnostic accuracy between compressed sensing (CS)-TOF and conventional parallel imaging (PI)-TOF-MRA for detecting and characterizing AVS. Methods This study was approved by the institutional review board for human studies. Participants comprised 56 patients who underwent both CS-TOF-MRA and PI-TOF-MRA on a 3-T MR unit with or without cerebral AVS between June 2016 and September 2018. Imaging parameters for both sequences were almost identical, except the acceleration factor of 3× for PI-TOF-MRA and 6.5× for CS-TOF-MRA, and the scan time of 5 min 19 s for PI-TOF-MRA and 2 min 26 s for CS-TOF-MRA. Two neuroradiologists assessed the accuracy of AVS detection on each sequence and analyzed AVS angioarchitecture. Concordance between CS-TOF, PI-TOF, and digital subtraction angiography was calculated using unweighted and weighted kappa statistics. Results Both CS-TOF-MRA and PI-TOF-MRA yielded excellent sensitivity and specificity for detecting intracranial AVS (reviewer 1, 97.3%, 94.7%; reviewer 2, 100%, 100%, respectively). Interrater agreement on the angioarchitectural features of intracranial AVS on CS-MRA and PI-MRA was moderate to good. Conclusion The diagnostic performance of CS-TOF-MRA is comparable to that of PI-TOF-MRA in detecting and classifying AVS with a reduced scan time under 2.5 min.

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“…CR values did not Introduction Time-of-Flight (TOF) Magnetic Resonance Angiography (MRA) is a non-invasive and contrast-media free MR technique that has been widely adopted in clinical institutions for intracranial vessel imaging in patients with suspected intracranial arterial disorders (stenosis, aneurysms etc.) [1][2][3][4][5][6][7][8]. TOF MRA has been shown to be a viable alternative to Digital Subtraction Angiography (DSA) [1][2][3][4][5][6][7][8].…”

Section: Resultsmentioning

confidence: 99%

“…[1][2][3][4][5][6][7][8]. TOF MRA has been shown to be a viable alternative to Digital Subtraction Angiography (DSA) [1][2][3][4][5][6][7][8]. However, conventional TOF-MRA imaging can be time consuming, especially when performing image acquisitions with sub-millimeter resolution [9].…”

Section: Resultsmentioning

confidence: 99%

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Clinical feasibility of ultrafast intracranial vessel imaging with non-Cartesian spiral 3D time-of-flight MR angiography at 1.5T: An intra-individual comparison study

Sartoretti

Schwenk

et al. 2020

PLoS ONE

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Clinical Evaluation of Highly Accelerated Compressed Sensing Time-of-Flight MR Angiography for Intracranial Arterial Stenosis

Abstract: Compressed sensing TOF both remarkably reduced the scan time and provided adequate image quality for the diagnosis of intracranial arterial stenosis.

Cited by 28 publications

References 25 publications

Novel Ultrafast Spiral Head MR Angiography Compared to Standard MR and CT Angiography

Novel Ultrafast Spiral Head MR Angiography Compared to Standard MR and CT Angiography

Evaluation of cerebral arteriovenous shunts: a comparison of parallel imaging time-of-flight magnetic resonance angiography (TOF-MRA) and compressed sensing TOF-MRA to digital subtraction angiography

Clinical feasibility of ultrafast intracranial vessel imaging with non-Cartesian spiral 3D time-of-flight MR angiography at 1.5T: An intra-individual comparison study

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