Clinical Evaluation of “Immunoaugmentative Therapy (IAT)”: An Unconventional Cancer Treatment

Pfeifer, Bernd L.; Jonas, Wayne B.

doi:10.1177/1534735403002002003

Cited by 4 publications

(2 citation statements)

References 10 publications

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“…Pfeifer and Jonas used a PODS approach to investigate Immuno-Augmentative Therapy (IAT), a CAM therapy used by thousands of cancer patients that had not been previously evaluated in a systematic fashion for either safety or efficacy. 28 This PODS demonstrated no significant improvement in cancer survival following IAT over expected outcomes when all patients were followed up. A previous best case series had reported positive outcomes for IAT.…”

Section: Evolution and Development Of Searchmentioning

confidence: 68%

Scientific Evaluation and Review of Claims in Health Care (SEaRCH): A Streamlined, Systematic, Phased Approach for Determining “What Works” in Healthcare

Jonas

Crawford

Hilton

et al. 2017

The Journal of Alternative and Complementary Medicine

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Background: Answering the question of “what works” in healthcare can be complex and requires the careful design and sequential application of systematic methodologies. Over the last decade, the Samueli Institute has, along with multiple partners, developed a streamlined, systematic, phased approach to this process called the Scientific Evaluation and Review of Claims in Health Care (SEaRCH™). The SEaRCH process provides an approach for rigorously, efficiently, and transparently making evidence-based decisions about healthcare claims in research and practice with minimal bias.Methods: SEaRCH uses three methods combined in a coordinated fashion to help determine what works in healthcare. The first, the Claims Assessment Profile (CAP), seeks to clarify the healthcare claim and question, and its ability to be evaluated in the context of its delivery. The second method, the Rapid Evidence Assessment of the Literature (REAL©), is a streamlined, systematic review process conducted to determine the quantity, quality, and strength of evidence and risk/benefit for the treatment. The third method involves the structured use of expert panels (EPs). There are several types of EPs, depending on the purpose and need. Together, these three methods—CAP, REAL, and EP—can be integrated into a strategic approach to help answer the question “what works in healthcare?” and what it means in a comprehensive way.Discussion: SEaRCH is a systematic, rigorous approach for evaluating healthcare claims of therapies, practices, programs, or products in an efficient and stepwise fashion. It provides an iterative, protocol-driven process that is customized to the intervention, consumer, and context. Multiple communities, including those involved in health service and policy, can benefit from this organized framework, assuring that evidence-based principles determine which healthcare practices with the greatest promise are used for improving the public's health and wellness.

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Section: Evolution and Development Of Searchmentioning

confidence: 68%

Scientific Evaluation and Review of Claims in Health Care (SEaRCH): A Streamlined, Systematic, Phased Approach for Determining “What Works” in Healthcare

Jonas

Crawford

Hilton

et al. 2017

The Journal of Alternative and Complementary Medicine

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“…Pfeifer and Jonas used a similar approach to investigate immuno-augmentative therapy, a CIM therapy used by thousands of cancer patients that had not been previously evaluated in a systematic fashion for either safety or efficacy. 7 The EDS was later taken over by Samueli Institute where it was further developed and renamed SEaRCH, which contained the CAP as the initial descriptive phase of CAM evaluation. 8 …”

Section: Methodsmentioning

confidence: 99%

Evaluating Integrative Cancer Clinics With the Claim Assessment Profile: An Example With the InspireHealth Clinic

et al. 2016

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Background: The evaluation of freestanding integrative cancer clinical programs is challenging and is rarely done. We have developed an approach called the Claim Assessment Profile (CAP) to identify whether evaluation of a practice is justified, feasible, and likely to provide useful information. Objectives: A CAP was performed in order to (1) clarify the healing claims at InspireHealth, an integrative oncology treatment program, by defining the most important impacts on its clients; (2) gather information about current research capacity at the clinic; and (3) create a program theory and path model for use in prospective research. Study Design/Methods: This case study design incorporates methods from a variety of rapid assessment approaches. Procedures included site visits to observe the program, structured qualitative interviews with 26 providers and staff, surveys to capture descriptive data about the program, and observational data on program implementation. Results: The InspireHealth program is a well-established, multi-site, thriving integrative oncology clinical practice that focuses on patient support, motivation, and health behavior engagement. It delivers patient-centered care via a standardized treatment protocol. There arehigh levels of research interest from staff and resources by which to conduct research. Conclusions: This analysis provides the primary descriptive and claims clarification of an integrative oncology treatment program, an evaluation readiness report, a detailed logic model explicating program theory, and a clinical outcomes path model for conducting prospective research. Prospective evaluation of this program would be feasible and valuable, adding to our knowledge base of integrative cancer therapies.

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Scanlan¹

2011

Complementary Medicine for Veterinary Technicians and Nurses

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Clinical Evaluation of “Immunoaugmentative Therapy (IAT)”: An Unconventional Cancer Treatment

Cited by 4 publications

References 10 publications

Scientific Evaluation and Review of Claims in Health Care (SEaRCH): A Streamlined, Systematic, Phased Approach for Determining “What Works” in Healthcare

Scientific Evaluation and Review of Claims in Health Care (SEaRCH): A Streamlined, Systematic, Phased Approach for Determining “What Works” in Healthcare

Evaluating Integrative Cancer Clinics With the Claim Assessment Profile: An Example With the InspireHealth Clinic

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