Clinical evaluation of lecithin as a lipid‐lowering agent

Abstract

The purpose of this investigation was to measure plasma lipid composition following oral administration of soybean lecithin in 32 patients with primary hyperlipidaemia. Lecithin granulate (Sternpur) was given for 30 days. Before starting the treatment and after 30 days of mangement blood was taken to establish the lipid concentration. Mean total cholesterol concentration was significantly decreased by 33%, while LDL-level was diminished by 38%. HDL-cholesterol concentration at the same time was increased significantly by 46%. Mean triglyceride concentration in these persons was significantly decreased by 33%. In conclusion, lecithin, a preparation obtained from soya, should be administered for the prevention and treatment of atherosclerosis.

Pollen composition and standardisation of analytical methods

“…A short review of the different quality criteria and on the methods used (analytical methods applied to the quality control of bee-pollen) Pollen collected by honey bees (bee-pollen) is promoted as a health food with a wide range of nutritional and therapeutic properties (Samochowiec and Wójcicki, 1981;Kosmider et al, 1983;Wójcicki et al, 1983;Lin et al, 1990;Iannuzzi, 1993;Wang et al, 1993;Dudov and Starodub, 1994;Liebelt et al, 1994;Yasumoto et al, 1995;Bevzo and Grygor'eva, 1997;Campos et al, 1997a;Linskens and Jorde, 1997;Bruneton, 1999;Haro et al, 2000;Cocan et al, 2005;Hamamoto et al, 2006;Yamaguchi et al, 2006). A high concentration of reducing sugars, essential amino acids, unsaturated and saturated fatty acids, the presence of Zn, Cu, Fe, and high K/Na ratio make honey bee pollen very important for human diets (Serra-Bonvehi and Escola-Jorda, 1997; Villanueva et al, 2002;Bastos et al, 2004;Almeida-Muradian et al, 2005).…”

Effect of Oxidized Phosphatidylcholine on Biomarkers of Oxidative Stress in Rats

“…In the present study, there was no significant difference in the weight of different organs of treated and untreated rats. Several authors reported the hypolipidemic effect of PC in rats and humans [38,39,[41][42][43]. The current study indicated that the rats treated with oxidized PC for 2 weeks (Group II) showed a significant increase in plasma cholesterol (P \ 0.05) and TG (P \ 0.01) content.…”

“…Lecithin has also been reported to produce cholesterol-lowering effects [38]. The lecithin administration has been suggested for the prevention and treatment of atherosclerosis [39]. It also reduces chemically induced hepatocarcinogenesis in rats and the growth of hepatic cancer cells [40].…”

Quantities of Phospholipid Molecular Classes in Japanese Meals and Prediction of Their Sources by Multiple Regression Analysis

“…Thus, it is considered that the daily intake of free choline, in addition to PC and SM may meet choline AI. Furthermore, in clinical studies, several reports regarding the effects of lecithin administration on blood lipid profile demonstrated a reduction in TAG, total cholesterol and low-density lipoprotein (LDL)-cholesterol levels, and an increase in high-density lipoprotein (HDL)-cholesterol levels in patients with hyperlipidemia (29,30), diabetes (31), or patients with hyperlipidemia on dialysis (32). Brook et al (29) .…”