Clinical Evaluation of Microneedling Therapy in the Management of Facial Scar: A Prospective Randomized Study

Bandral, Manjunatha Reddy; Padgavankar, Pritish Harish; Japatti, Sharanbasappa; Gir, Priyadarshani J.; Siddegowda, Chidambar Y; Gir, Rushikesh J

doi:10.1007/s12663-018-1155-7

Cited by 27 publications

(19 citation statements)

References 11 publications

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“…Further studies about clinical application of PCI for the treatment of scars of various etiologies were reported [8, 12, 14, 20, 23-26, 28, 32-37] with similar results. In one study labeled as a prospective randomized study [36], results of PCI in 50 patients with facial acne scars, traumatic scars, hypertrophic scars and scars with skin discoloration were assessed by three evaluators comparing preoperative and postoperative clinical photographs. Unfortunately, validity of evaluating skin appearance and texture based on 2D clinical photographs is highly questionable due to inconsistent quality of photographs that may vary by image composition (magnification, angle, perspective) or exposure (luminance, contrast, white balance, focus/depth of field) responsible for low reproducibility of clinical outcome.…”

Section: Discussionmentioning

confidence: 99%

“…Studies have observed that effects of microneedling changed over several months to reach a maximum at 3-6 months [6]. Time to follow-up was not specified in 4 clinical studies [8,25,33,36], and 4 others reported a follow-up period shorter than 3 months [15,23,32,37]. It must be noted though that multiple sittings were performed in many studies and the time to follow-up was from the last sitting.…”

Section: Discussionmentioning

confidence: 99%

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Microneedling: Percutaneous Collagen Induction (PCI) Therapy for Management of Scars and Photoaged Skin—Scientific Evidence and Review of the Literature

Atiyeh

Ghanem

Chahine³

2020

Aesth Plast Surg

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Demand for safe, less aggressive and cost-efficient treatment modality to improve skin quality and appearance following scarring or photoaging is increasing steadily. A treatment modality that preserves the epidermis while promoting regeneration rather than cicatrization would be ideal. Percutaneous collagen induction (PCI) therapy or microneedling is claimed to approach this ideal objective. The current comprehensive literature review is intended to analyze the scientific basis supporting this therapeutic modality and to evaluate the efficacy of PCI microneedling therapy versus no treatment of patients with photoaged skin and scars of various etiologies on aesthetic skin rejuvenation, skin tightening and scar quality in prospective, retrospective and experimental studies. Twenty-five published studies were identified and included in this review. Four publications are experimental animal studies; most clinical reports are case series or small cohort non-randomized studies or trials lacking methodological unity with a heterogenous mix of scars, wrinkles and skin laxity being treated. The majority are studies about management of scars of various etiologies while only 4 specifically investigated the effect of PCI on wrinkles and aging skin. One study compared burn scar erythema in the treated area to the untreated area, and 5 studies included histologic evaluation of biopsies. Despite PCI promising therapeutic benefits and its increasing cosmetic applications, the current literature review unfortunately revealed a limited number of high-quality studies mostly experimental. Data and conclusions of clinical studies must be carefully interpreted before translating the evidence presented into clinical recommendations.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Microneedling: Percutaneous Collagen Induction (PCI) Therapy for Management of Scars and Photoaged Skin—Scientific Evidence and Review of the Literature

Atiyeh

Ghanem

Chahine³

2020

Aesth Plast Surg

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“…Percutaneous collagen induction (PCI) therapy, also known more commonly as microneedling, is another non-energy-based treatment that is widely used to treat not only facial scars, such as acne scars, but also fine lines, wrinkles, rhytids, melasma, and other age-related dermatological conditions. 60 , 61 Microneedling entails creating hundreds of pin-sized holes in the skin to stimulate rejuvenation of healthy skin. 62 This technique was first developed in the early 21st century and many histometric studies since have reported increased epidermal thickness, upregulated elastin fiber and collagen lattice formation, and release of various regenerative growth factors in days and weeks following treatment.…”

Section: Microneedlingmentioning

confidence: 99%

A Comprehensive Review of Non-Energy-Based Treatments for Atrophic Acne Scarring

Tam¹,

Khong²,

Tam³

et al. 2022

CCID

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Scarring is a dire consequence of acne vulgaris. Particularly, atrophic acne scarring is highly prevalent among young adults, and its physical and psychological effects can persist throughout their lives if left untreated. This literature review will analyze various non-energy-based approaches to treating atrophic acne scarring, emphasizing recent advances within the last 5 to 10 years. To accomplish this, we performed a PubMed search for various acne scar treatments such as chemical peels, dermabrasion, microdermabrasion, subcision, microneedling, punch techniques, dermal fillers, and thread lifting. Our findings and analysis show that there is no panacean solution to treating atrophic acne scars, which explains the evolving trend towards developing unique combinatorial treatments. Although a fair comparison of each treatment approach is difficult to achieve due to the studies’ varying sample sizes, strength of evidence, treatment execution, etc, there still remains a level of consensus on what treatments are well suited for particular scar types.

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“…Microneedling is a non‐invasive procedure that uses needles to create controlled skin injury. There are various needling devices including Dermaroller ® (Dermaroller GmbH); Dermapen™ (Equipmed) Derma‐Stamps™ (Dermaroller) that use needles made of silicon, titanium, polymers, and even glass 40 …”

Section: Treatment Of Keloid and Hypertrophic Scarsmentioning

confidence: 99%

Update on management of keloid and hypertrophic scars: A systemic review

Elsaie

2021

J of Cosmetic Dermatology

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Numerous therapeutic strategies have been described for prevention and reduction of hypertrophic scars and keloids, but none of the treatments is effective in all patients. No universal consensus in treatment regimen has been established, and there is limited evidence‐based literature to guide the correct management. The process of scar development is complex and requires deeper understanding of the molecular mechanisms that cause their development and recurrences. Despite many available modes of targeting keloid and hypertrophic scars, yet they remain an ongoing challenge to patients and clinicians. To date, no one therapy has been universally accepted as the gold standard for the treatment of all excessive scars nor has the capability of complete scar resolution The search of literature included peer‐reviewed articles including clinical trials and scientific reviews. Literature was identified from electronic databases (MEDLINE/PubMed) through May 2021 and references of respective articles and only the articles published in English language were included.

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Clinical Evaluation of Microneedling Therapy in the Management of Facial Scar: A Prospective Randomized Study

Cited by 27 publications

References 11 publications

Microneedling: Percutaneous Collagen Induction (PCI) Therapy for Management of Scars and Photoaged Skin—Scientific Evidence and Review of the Literature

Microneedling: Percutaneous Collagen Induction (PCI) Therapy for Management of Scars and Photoaged Skin—Scientific Evidence and Review of the Literature

A Comprehensive Review of Non-Energy-Based Treatments for Atrophic Acne Scarring

Update on management of keloid and hypertrophic scars: A systemic review

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