Clinical evaluation of particulate allogeneic with and without autogenous bone grafts and resorbable collagen membranes for bone augmentation of atrophic alveolar ridges

Abstract

Large vertical and/or horizontal ridge deficiencies may be treated with FDBA and ribose cross-linked collagen barrier membranes with good clinical outcome. No added effect of the application of a layer of autogenous bone in these bone augmentation procedures could be demonstrated. Spontaneous membrane exposure was the only parameter to affect the degree of new calcified tissue formation.

The effect of membrane exposure on lateral ridge augmentation: a case-controlled study

“…Still, even resorbable membranes show frequent events of membrane exposures after GBR procedures. For example, between 22 and 32% of early membrane exposure have been reported for collagen membrane by several authors [15–18]. A major drawback of collagen membrane might be that lose their integrity in 1 week [18] when exposed to the proteolytic environment of the oral cavity that leaves the graft material unprotected and can lead to graft loss.…”

Management of Failed Alveolar Bone Grafts

“…8 Beitlitum et al described their experience using particulate allograft bone to augment atrophic alveolar ridges in 50 patients. 9 They demonstrated effective augmentation of deficient alveolar ridges using allograft particulate bone grafts with and without the addition of autogenous bone.…”

Is Canine Eruption Velocity Affected by the Presence of Allograft Within a Repaired Alveolar Cleft?

“…Recently, hybrid formulations of allograft and autograft have been shown to result in stable repair of alveolar defects in patients with mixed dentition, with shorter operating times, improved bony healing, and no extrusion of bone graft material. 7 Although these results are encouraging, the rate of complete eruption was higher in the autograft group compared with the hybrid group, potentially an effect of follow-up time or innate differences in canine eruption velocity in allograft versus autograft.…”

“…1,2,6 Hybrid formulations of autograft and allograft bone have been used successfully to repair deficient alveolar ridges. 7 Advantages of the hybrid mix are the presence of osteocytes within the mixture, adequate volume, and potentially decreased donor-site morbidity with minimal access harvest. Recently, hybrid formulations of allograft and autograft have been shown to result in stable repair of alveolar defects in patients with mixed dentition, with shorter operating times, improved bony healing, and no extrusion of bone graft material.…”