Clinical evaluation of patients suffering from osteoarthritis along with prevalence, pharmacological and non-pharmacological treatment Authors

Abstract

Background: Osteoarthritis is a disorder of joints that most often influences the knee, spine, hip, and small hands joints. It is one of the common types of arthritis. It can lead to reduced mobility in elder patients. Primary objective: The aim of the project is to evaluate the current etiology, pathogenesis, investigations, and management of osteoarthritis. Methods/Design: The history of patients suffering from osteoarthritis was collected on a designed questionnaire which includes age, gender, job status, duration of disease, weight, pain, and current medical history. Setting: Data was taken from different people in the community Participants: Data from 50 patients were taken. Intervention: This work will discuss the challenges of developing good quality outcome measures for use in large-scale multicenter clinical trials for new osteoarthritis treatments, especially disease-modifying osteoarthritis drugs. Primary Outcome Measures: The data evaluation showed that this disease is most common in women than men having a weight greater than 50kg. Results: Most persons suffering from this disease were unemployed and had limited physical activities, and the maximum had complaints of knee pain and shoulder pain. A few patients complained of neck, elbow, feet, and backbone pain. Most were suffering from other concomitant diseases along with osteoarthritis, and a few were diagnosed with osteoarthritis only. Conclusion: This study clearly showed the prime factors involved in osteoarthritis which may help the community to avoid those factors to increase the quality of life.

Synthesis, characterization and evaluation of anti-arthritic and anti-inflammatory potential of curcumin loaded chitosan nanoparticles

“…Arthritis affects millions of people worldwide. The disease causes severe joint pain, stiffness, and swelling, which could result in disability if not managed effectively 2 . Rheumatoid arthritis (RA) is a severe autoimmune disorder that affects about 1% of the world's population and is associated with generous disability and mortality.…”