Clinical evaluation of treatment of gonorrhea in the female

New Antibiotics

“…In comparative trials in females, a dose of 4 g of spectinomycin (2 g in each buttock) has been shown to be comparable in efficacy with a single 2.4 mega unit dose of aqueous procaine benzylpenicillin (Lucas et al, 1967;Shapiro and Lentz, 1967). The study of Lucas et al (1967) involved 1,318 patients with acute uncomplicated gonorrhoea.…”

Consumption of antibiotics in Greenland, 1964-70. 3. Effect of coincidental administration of antibiotics on gonorrhoeal infections.

“…This is particularly true when the treatment used has a low rate of cure against infections caused by strains with reduced sensitivity (Krook and Juhlin, 1965). It is sometimes recommended, therefore, that a more intensive treatment should be used in females (Shapiro and Lentz, 1967;Lucas, 1971). It is difficult to determine whether the lower cure rate often found Received for publication July 7, 1972 in gonorrhoeal proctitis in females (Scott and Stone, 1966; Molin and Nystr6m, 1970) is due to the fact that these infections have lasted longer than in cases without proctitis, or to the failure of the drug used to reach curative levels in the rectum as well as in the urogenital tract.…”