Clinical evidence for acupuncture for adult asthma: Systematic review and meta-analysis of randomised sham/placebo-controlled trials

Pang, Jinhui; Shergis, Johannah Linda; Zheng, Li; Liu, Shaonan; Guo, Xinfeng; Zhang, Anthony Lin; Lin, Lin; Xue, Charlie Changli; Wu, Lei

doi:10.1016/j.ctim.2023.102956

Cited by 1 publication

(2 citation statements)

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“… 134 Therefore, more high-quality studies are needed to clarify the duration of acupuncture, improvement of clinical symptoms, adverse effects, and even reactions related to immune mechanisms. 23 However, even with the above problems, a large clinical acupuncture trial has revealed that acupuncture therapy for allergic asthma improves health-related quality of life compared with no acupuncture therapy 24 and can even replace some placebos with side effects. 135 This indicates that acupuncture therapy as an effective measure of CAM can improve the clinical effects of anti-asthma drugs and relieve symptoms of asthma.…”

Section: Discussionmentioning

confidence: 99%

“…22 These acupoints are mainly located on the lung meridian, conception vessel, stomach meridian, and bladder meridian, and these points are in agreement with a meta-analysis and data from Chinese clinical practice. [23][24][25] Apart from the common acupoints mentioned above, other auxiliary points are also essential to relieve the syndrome of asthma, for example, Yuji (LU10), Lieque (LU7), Fenglong (ST40), and Fuliu (KI7). The acupoints are mainly distributed in the back region and limbs of the body (Table 1, Figure 2).…”

Section: Acupoints For Asthmamentioning

confidence: 99%

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Research on the Mechanism and Application of Acupuncture Therapy for Asthma: A Review

Wang,

Jin

2024

JAA

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Asthma is a high-risk disease based on airway hyperresponsiveness (AHR). In this review, we found that there are many studies on clinical therapy for asthma that focus on the efficacy of acupuncture therapy and its mechanisms, including the functional connectivity of different brain regions, with the aid of functional magnetic resonance imaging (fMRI), immune responses/cell recognition (innate lymphoid cells and balance of Th1/Th2 and Treg/Th17), intracellular mechanism (autophagy, endoplasmic reticulum stress, and epigenetic alteration), and ligand-receptor/chemical signaling pathway (neurotransmitter, hormone, and small molecules). In this review, we summarized the clinical and experimental evidence for the mechanisms of acupuncture therapy in asthma to offer insights into drug discovery and clinical therapy. Given the paucity of clinical studies on the mechanisms of acupuncture in the treatment of asthma, this review notably included studies based on animal models to investigate the mechanisms of acupuncture in the treatment of asthma.

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