Clinical evidence of benefits of a dietary supplement containing probiotic and carotenoids on ultraviolet-induced skin damage

Abstract

Nutritional supplementation combining a specific probiotic (La1) and nutritional doses of carotenoids reduced early UV-induced skin damage caused by simulated or natural sun exposure in a large panel of subjects (n=139). This latter result might suggest that DS intake could have a beneficial influence on the long-term effects of UV exposure and more specifically on skin photoageing.

Can dietary intake influence perception of and measured appearance? A Systematic Review

“…Thirteen studies had two intervention arms (control/intervention) [25][26][27][29][30][31][32][33][34][35][36][37][38], two had one arm [29] , one had three [39] and one had six intervention arms [28]. The majority of studies (15 out of 17) evaluated the effect of various dietary supplements with several active…”

“…Polyphenols [27,39], Omega 3 fatty acids [27,32,39], carotenoids [21], [32,36], [27,37] , vitamins E [27,36,37,39] and C [36] [27,37], Lactobacillus (La1) probiotics [29], green tea polyphenols [25,30,33], squalene [31], red ginseng [26] , and flavanol cocoa [34], whilst only one measured the effect derived from whole foods [28] which used foods high in beta-carotene.…”

“…Three clinical trials [29] evaluated the effect of a dietary supplement containing lactobacillus (La1) and 7.2mg carotenoids (beta-carotene and lycopene) on UVR exposed skin, using three levels of exposure; extreme (UV-SSR), moderate (UV-DL) and natural summer sunlight.…”

“…Trial one assessed early markers of UVR-induced skin damage using histology and immumohistochemistry [29]. In trial two, a chromameter was used to evaluate skin color changes, while in trial three both dermatologists and subjects completed assessment questionnaires on skin resistance to sun exposure [29].…”

“…In trial two, a chromameter was used to evaluate skin color changes, while in trial three both dermatologists and subjects completed assessment questionnaires on skin resistance to sun exposure [29]. There were significant increases in minimal erythema dose (MED) (threshold required to produce sunburn) after six weeks of dietary supplement (DS) intake (p<0.05).…”