Clinical factors in predicting acute renal failure caused by rhabdomyolysis in the ED

Chen, Chun-Yu; Lin, Yan Ren; Zhao, Lulu; Yang, Wen-Chieh; Chang, Yu-Jun; Wu, Han-Ping

doi:10.1016/j.ajem.2013.03.047

Cited by 55 publications

(48 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Thus, we consider that the AKI was not caused by rhabdomyolysis, but by hypovolemia from heat stroke. The elevation of serum creatinine is potentially caused by muscle injury by heat stroke, thereby meeting the AKI criteria [3,[6][7][8][9].…”

Section: Discussionmentioning

confidence: 99%

Increased Creatinine Clearance in Acute Kidney Injury due to Heat Stroke

Urabe¹,

Kotani²,

Tsujimoto³

2018

J Med Cases

View full text Add to dashboard Cite

Acute kidney injury (AKI) is associated with increased mortality and risk of chronic kidney disease (CKD). Whereas AKI is well known to occur frequently in patients with heat stroke, creatinine clearance levels of these patients have not been evaluated in literature. In this report, we present the case of a patient with increased creatinine clearance who developed AKI due to heat stroke. A 40-year-old male with no past medical history was admitted to the intensive care unit of our hospital due to AKI from heat stroke. Although he was diagnosed with stage 3 AKI at admission, his creatinine clearance, measured by a 12-h urine collection, was highly elevated to 230 mL/min/1.73 m 2 . His serum creatinine was decreased to the baseline level 12 h after admission, with fluid resuscitation. This case can suggest that creatinine clearance might be underestimated, although serum creatinine levels are elevated in AKI due to heat stroke.

show abstract

Section: Discussionmentioning

confidence: 99%

Increased Creatinine Clearance in Acute Kidney Injury due to Heat Stroke

Urabe¹,

Kotani²,

Tsujimoto³

2018

J Med Cases

View full text Add to dashboard Cite

show abstract

“…10 Farklı pediatrik rabdomiyoliz serilerinde akut renal hasar %3,3-8,7 arasında bildirilmiştir. 2,[11][12][13] Rabdomiyolizde akut renal zedelenmeye neden olan birkaç mekanizma vardır; miyoglobinin direkt renal hasarı, intrarenal vazokonstrüksiyon ve tü-büler obstrüksiyon. 10 Kas yıkımı sonucu oluşan miyoglobin ekstraselüler sıvıya geçer, glomerül-lerden süzülür, proksimal tübüllerden reabsorbe edilir.…”

unclassified

“…13 Agresif hidrasyon zedelenen kastan sıvı kaybını dengeler, renal iskemiyi önler ve miyoglobin eliminasyonunu sağlar. İdrar alkalinizasyonunun ise idrarda silendir oluşumunu önleyerek ve antioksidan etki yaparak yararlı olduğu rapor edilmektedir.…”

unclassified

“…İntra-venöz mannitol infüzyonu; ozmotik diürez, renal vazodilatasyon ve serbest radikalleri uzaklaştırma yolu ile etkili olmaktadır. 13 Yüksek etkinliğinin yol açtığı komplikasyonlar nedeni ile, çocuklarda rabdomiyolize bağlı gelişen akut renal zedelenme tedavisinde öncelikli kullanımda önerilmemektedir. Bizim olgumuzda; bikarbonatlı, SF'ye denk sodyum içeren sıvı tedavisi ile mannitol tedavisine gerek kalmadan renal zedelenmenin yol açtığı klinik ve biyokimyasal parametreler kontrol edilebilmiş ve olgu günler içinde düzelmiştir.…”

unclassified

See 1 more Smart Citation

A Rare Cause of Acute Renal Damage Followed by an Initial Diagnosis of STEC HUS: Rhabdomyolysis: Case Report

Saribaş¹,

Ekinci²

2015

Turkiye Klinikleri J Pediatr

View full text Add to dashboard Cite

“…More specifically, a better association was found between serum creatinine and serum myoglobin (r = 0.33; p < 0.001) than between serum creatinine and CK (r = 0.15; p = 0.01). Interestingly, when patients were grouped by CK Additional support to the use of serum myoglobin assessment for predicting AKI emerged from the study of Chen et al [10], who studied 202 patients admitted to the emergency department with a definite diagnosis of rhabdomyolysis. The leading causes of rhabdomyolysis were trauma and infections, both conditions accounting for approximately half of all patients.…”

mentioning

confidence: 99%