Clinical Features and Dynamics of Blood Pressure in Children at the Age of 6 Months, Born in the Period of Early Preterm Labor.

Abstract

Children born at the time of early preterm labor (SPR) are a group with a high risk of developing cardiovascular diseases, including arterial hypertension, which can occur throughout their lives. Currently, the issues of diagnosis of high blood pressure in this category of children are relevant. Our aim of the study is to identify the clinical features and features of changes in the dynamics of blood pressure in children aged 6 months born at the time of early preterm labor. At 6 months of age, children born at the time of early preterm labor have low indicators of physical development, manifestations of vegetative-vascular dysfunction, cardiac arrhythmias, high blood pressure. High normal blood pressure was registered in 16.7% of subgroup 1 and 29.2% of subgroup 2, 13.6% in children of the comparison group (p1-2=0.001; p1-3=0.001; p2-3=0.004). Arterial hypertension was diagnosed only in the main group: 41.7% of children of subgroup 1, and 29.2% in subgroup 2 (p1-2=0.001; p1-3=0.001; p2-3=0.004). The results of laboratory data showed a statistically significant increase in the level of renin and angiotensin II in venous blood in children of the main group than in children of the comparison group. The highest levels of renin and angiotensin II were found in children weighing 500-750g. Children born in the period of early preterm labor require monthly monitoring of blood pressure levels and the development of individual dynamic monitoring programs.