Clinical Features and Management of “Phlebitis-like Abnormal Reaction” After Cyanoacrylate Closure for the Treatment of Incompetent Saphenous Veins

Allergic contact dermatitis with systemic symptoms caused by VenaSeal

“…1 Park et al described a phlebitis-like abnormal reaction in 25% of patients treated with VenaSeal, which could be considered a hypersensitivity reaction to the compound. 2 Nasser et al reported a new case of phlebitis-like reaction with good response to oral corticosteroids. 3 Recently, Watts et al described a new case of allergic contact eczema at VenaSeal application site.…”

Audit of the efficacy and complications of cyanoacrylate glue embolisation to treat varicose veins in primary care

“…This percentage is in line with other reports. 11,12,15 Current discussion on post Venaseal TM phlebitis argues that it is not true phlebitis but a phlebitis-like, abnormal reaction due to type IV hypersensitivity, because it is too widespread, lasting 7-14 days with predilection to CAGE-treated truncal veins. 22 Our current practice is to allow the condition to run its course and prescribe anti-inflammatories and class II compression stockings for symptomatic relief only.…”

“…CAGE removes the need for TLA and use of compression stockings and reduces the risk of sensory nerve damage. 11,12 It is an office-based procedure that uses a medical adhesive (n-butyl-2-cyanoacrylate (CA)) to seal the target truncal varicose vein, requiring only a small stab incision for insertion under local anaesthesia. 11 In our practice, all patients have an initial assessment with explanation and information regarding all possible treatments, their benefits and potential adverse effects and complications.…”

“…We wished to establish whether our CAGE procedures have similar efficacy and adverse events rates as are reported in the literature. [9][10][11][12][13]15,16 Methods Data were collected from 0800 Vein Dr, a primary care vein clinic with branches in Hastings, Palmerston North and Auckland. We retrospectively reviewed the clinical records of 107 consecutive patients who underwent CAGE with the Venaseal TM Closure System between 11 November 2015 and 12 December 2017.…”

The 11th Japan-Korea Joint Meeting for Vascular Surgery

“…And more common in epi-fascial GSV (45.8%) than in subfascial GSV (23.2%) (p=.001). [1][2][3] Second, sometimes an additional glue injection is efficient to treat the large vein. IFU recommends injection of 0.1 cc glue for every 3 cm, but some literatures recommend an additional injection in case of large diameter vein.…”