Clinical features and management of kaposiform hemangioendothelioma and tufted angioma: Similarities and differences

Zhou, Jiangyuan; Yang, Kaiying; Dai, Shiyi; Qiu, Tong; Zhang, Xuepeng; Gong, Xue; Chen, Siyuan; Ji, Yi

doi:10.1016/j.jaad.2021.07.012

Cited by 13 publications

(9 citation statements)

References 5 publications

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“…The most common lesions of KHE occur in limbs (7). However, in current studies on KHE, there were no cases with symmetric limbs involved and confined to the bone.…”

Section: Discussioncontrasting

confidence: 60%

Case Report: Bilateral symmetrical primary kaposiform hemangioendothelioma of the femur

et al. 2022

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Kaposiform hemangioendothelioma (KHE) is a rare borderline vascular tumor that usually presents as a mass of skin or deep soft tissue. We report a unique case of an 8-year-old KHE patient with bilateral symmetrical sites involving both femurs. The laboratory, radiographic, and pathological findings of the patient were minutely described. During the 6-month follow-up, the symptoms of pain and dysfunction of this patient were relieved. This study aimed to arouse clinicians’ concern about the symmetrical sites of KHE patients.

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“…The most common lesions of KHE occur in limbs (7). However, in current studies on KHE, there were no cases with symmetric limbs involved and confined to the bone.…”

Section: Discussioncontrasting

confidence: 60%

Case Report: Bilateral symmetrical primary kaposiform hemangioendothelioma of the femur

et al. 2022

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“…In this study, 12 patients showed purpura-like skin changes and 14 had red or purplish skin changes, with 4 showing extensive skin lesions presenting as diffuse masses or swelling of the limbs, which suggested local infiltrative growth. Interestingly, Kaposiform hemangioendothelioma (KHE) and tufted hemangioma (TA) have overlapping clinical and histopathological features [ 11 ]. Therefore, hematological tests and imageological examinations should be performed in infants and children with the abovementioned symptoms.…”

Section: Discussionmentioning

confidence: 99%

Clinical and imaging features of Kaposiform hemangioendothelioma in infants

Hu¹,

Song²,

Wu³

et al. 2023

Heliyon

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“…However, sirolimus has recently emerged as a treatment option for complicated vascular anomalies and tumors in children, including KHE with or without KMP (5). Experience so far suggests that systemic sirolimus with or without corticosteroids is needed for most patients with KHE (6). Sirolimus plus steroids are now considered as first-line therapy for the treatment of KHE with KMP (2).…”

Section: Discussionmentioning

confidence: 99%

Case report: Experience of a rare case of rebound of the Kasabach-Merritt phenomenon during sirolimus treatment in kaposiform hemangioendothelioma

Wang

Wu³

et al. 2022

Front. Pediatr.

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Kaposiform hemangioendothelioma (KHE) is a rare vascular neoplasm associated with the Kasabach–Merritt phenomenon (KMP), which is a consumptive coagulopathy with associated potentially life-threatening thrombocytopenia. There are no standardized treatment protocols for the management of KHE with KMP. Moreover, there are limited reports regarding the treatment of cases of rebound. Herein, we describe a rare case of rebound of KHE/KMP, during systemic sirolimus treatment, successfully treated with embolization and vincristine infusion combined with microwave ablation.

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Clinical features and management of kaposiform hemangioendothelioma and tufted angioma: Similarities and differences

Cited by 13 publications

References 5 publications

Case Report: Bilateral symmetrical primary kaposiform hemangioendothelioma of the femur

Case Report: Bilateral symmetrical primary kaposiform hemangioendothelioma of the femur

Clinical and imaging features of Kaposiform hemangioendothelioma in infants

Case report: Experience of a rare case of rebound of the Kasabach-Merritt phenomenon during sirolimus treatment in kaposiform hemangioendothelioma

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