Clinical features and outcomes of pregnant women suspected of coronavirus disease 2019

Yang, Hui; Sun, Guoqiang; Tang, Fei; Peng, Min; Gao, Ying; Peng, Jing; Xie, Hui; Zhao, Yun; Jin, Zhichun

doi:10.1016/j.jinf.2020.04.003

Cited by 145 publications

(168 citation statements)

References 7 publications

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“…Recently published case series discuss clinical features and outcomes of pregnant women with suspected COVID-19. [1][2][3][4] In 1 series of 13 mothers with confirmed SARS-CoV-2 infection postpartum, 2 had a dry cough and 6 had ground-glass opacity infiltrates on chest CT. 1 In another retrospective single-centre study, 7 pregnant (third-trimester) women who tested positive for SARS-CoV-2 infection had infiltrates on CT consistent with infection but did not require intensive care postpartum. 2 Of a total of 20 reported patients, none developed postpartum acute decompensation.…”

Section: Discussionmentioning

confidence: 99%

“…2 Of a total of 20 reported patients, none developed postpartum acute decompensation. 1,2 Two recent reports from the same institution in New York described 29 women who had been asymptomatic but tested positive for SARS-CoV-2 infection on screening just before delivery. 3,4 Three women (out of 29) developed fever postpartum; in 2 of these women, the fever was thought to be related to endomyometritis, and in 1 woman, the fever was thought to be related to COVID-19.…”

Section: Discussionmentioning

confidence: 99%

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Postpartum exacerbation of antenatal COVID-19 pneumonia in 3 women

Wood

et al. 2020

CMAJ

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A 31-year-old pregnant woman (38 wk + 2 d) presented to the obstetrics and gynecology team with a 5-day history of cough, low-grade fever (maximum temperature 37.8°C) and intermittent shortness of breath. She also described bilateral lower-leg edema for 2 days. Because she reported contact with a potentially infected person from Wuhan, China, the epicentre of the coronavirus disease 2019 (COVID-19) outbreak, we placed her immediately in respiratory isolation.The patient's oxygen saturations were 90%-94%, respiratory rate was 28 breaths/min, heart rate was 90 beats/min and blood pressure was 160/100 mm Hg at the time of admission. Results of initial laboratory tests were as follows: leukocyte count 5.1 (reference range 3.5-9.5) ×10 9 /L, lymphocyte count 1.05 (reference range 1.1-3.2) ×10 9 /L and C-reactive protein (CRP) level 7.1 (reference range 0-8) mg/L. Real-time polymerase chain reaction (PCR) testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was positive. Fetal ultrasonography and maternal echocardiography were normal.We performed low-dose computed tomography (CT) of the chest to exclude pulmonary embolism and pneumonia; CT results were normal ( Figure 1A). After a failed induction of labour, the patient underwent a cesarean delivery, delivering a healthy boy weighing 4.2 kg. The newborn tested negative for SARS-CoV-2 by real-time PCR throat and anal swabs. After delivery, we prescribed the patient an antiviral treatment typically used for influenza, umifenovir. PRACTICE | CASES CPD

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Postpartum exacerbation of antenatal COVID-19 pneumonia in 3 women

Wood

et al. 2020

CMAJ

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“…Contradictory to the previous research showing that pleural effusion has no speci c type in patients with novel coronary pneumonia [16], the study found that severe patients are more likely to develop pleural effusion. The main reason is that the sample size of the previous study is too small.…”

Section: Discussionmentioning

confidence: 52%

Clinical Characteristics of COVID-19 and the Value of Mulbsta Scoring System in Prognosis Evaluation

Wang

Luo

et al. 2020

Preprint

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BackgroundCOVID-19, a worldwideinfectious disease, has killed more than 420000 people, whichis extremely harmful.MethodsIn this single-center retrospective study, we included the novel coronavirus pneumonia confirmed in our hospital. This study collected the basic information andclinical examination features.ResultsThe enrolled 704 patients were affirmed infected with 2019-nCoV by the test of throat swabs. There are 334 men and 369 women, and gender, age, combined with basic diseasesare distinct in diverse disease classification (p<0.05). From the symptom analysis, the proportion of fever over 38 degrees, dyspnea, fatigue, poor appetite and other symptoms is diverse in different types of diseases (p<0.05). As the severity of the disease increases, the median lymphocyte count decreases, C-reactive protein increase, erythrocyte sedimentation rateincrease, albumin decrease, pleural effusion increase, D-Dimer and NT-proBNP increase significantly (p<0.05).As the disease severity increases, the average value of MuLBSTA score obviously ascend (p<0.05), MuLBSTA scoring system predicts novel coronavirus pneumonia patients' prognosis is still insufficient, and may require additional indicators including anorexia, fatigue, C reactive protein, etc (p<0.05).ConclusionThe MuLBSTA evaluation system has certain value for the evaluation of the disease, but it needs to be improved.

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“…Fehlgeburten treten während der SARS-CoV-2 Pandemie bisher nicht häufiger auf, die Datenlage ist aber für eine abschließende Beurteilung noch unzureichend [12,20]. Die Frühgeburtenraten variieren je nach Studie zwischen 15 und 39 % [21,22].…”

Section: Schwangerschaftskomplikationenunclassified

Aktualisierte Empfehlungen zu SARS-CoV-2/COVID-19 und Schwangerschaft, Geburt und Wochenbett

Zöllkau

Hagenbeck

Hecher

et al. 2020

Z Geburtshilfe Neonatol

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ZusammenfassungMit Beginn der SARS-CoV-2 Pandemie haben die deutschen geburtshilflichen und pädiatrischen Fachgesellschaften im März 2020 Empfehlungen zur Versorgung infizierter Schwangerer und deren Neugeborener, wie auch notwendige Schutzmaßnahmen für das Personal veröffentlicht [1–3]. Eine Aktualisierung ist aufgrund des rasanten Wissenszuwachses notwendig. Die vorliegende Empfehlung versteht sich daher als Fortschreibung der bereits vorliegenden Publikationen [1–3].Von der Cochrane Pregnancy and Childbirth Group wurden weltweit nationale Empfehlungen verglichen und als Review veröffentlicht [4]. In methodischer Anlehnung hieran nehmen die vorliegenden aktualisierten Empfehlungen Stellung zu den Kernfragen der prä-, peri- und postnatalen Betreuung bei SARS-CoV-2 und COVID-19, auf der Grundlage der bis zum 30.05.2020 verfügbaren Publikationen. Die Stellungnahmen basieren auf einem sorgfältig abgestimmten ExpertInnenkonsens und können sich – insofern neue Erkenntnisse veröffentlicht werden – zeitnah ändern.Die Verantwortung für das konkrete Vorgehen bleibt bei dem vor Ort medizinisch betreuenden Team, dessen Entscheidungen durch diese Empfehlung unterstützt werden sollen.

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Clinical features and outcomes of pregnant women suspected of coronavirus disease 2019

Cited by 145 publications

References 7 publications

Postpartum exacerbation of antenatal COVID-19 pneumonia in 3 women

Postpartum exacerbation of antenatal COVID-19 pneumonia in 3 women

Clinical Characteristics of COVID-19 and the Value of Mulbsta Scoring System in Prognosis Evaluation

Aktualisierte Empfehlungen zu SARS-CoV-2/COVID-19 und Schwangerschaft, Geburt und Wochenbett

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