Clinical features, causes, treatments, and outcomes of peristomal pyoderma gangrenosum (PPG) in 44 patients: The Mayo Clinic experience, 1996 through 2013

Peristomal pyoderma gangrenosum: 12‐year experience in a single tertiary referral centre

“…also reported high recurrence of PPG after stoma relocation . Like Barbosa et al ., Poritz et al . also reported that stoma closure, but not stoma relocation, was highly effective in the management of PPG .…”

“…PPG is a rare dermatological condition, and there have been limited case series on PPG in the literature. Notable studies on PPG include studies by the Cleveland Clinic ( n = 15), the Mayo Clinic ( n = 43), Funayama et al . ( n = 17) and Sheldon et al .…”

“…Due to its rarity, peristomal pyoderma gangrenosum (PPG) is often misdiagnosed, and there is often a delay in appropriate management. While there is an increasing body of literature on pyoderma gangrenosum, there is a scarcity of relevant literature specifically on PPG, with few case reports and several small case series . PPG is associated with rapidly progressive ulceration, with dermal neutrophilia and tissue necrosis, and ulcers may be associated with peristomal abscesses.…”

“…Both medical and surgical therapies have been described, with various management strategies reported. The recurrence rate is high .…”

“…Both medical and surgical therapies have been described, with various management strategies reported. The recurrence rate is high . The aetiology of PPG is unknown, but inflammatory bowel disease (IBD), autoimmune diseases and trauma have been associated with pyoderma gangrenosum.…”