Clinical Features, Diagnosis, the Results of Therapeutic and Surgical Treatment of Acanthamoebic Keratitis

Kasparova, Evg A; Kasparov, A A; Marchenko, N R; Федоров, А. А.; Egorova, G B; Kobzova, M V; Mitichkina, T S

doi:10.18008/1816-5095-2017-4-306-314

Cited by 2 publications

(1 citation statement)

References 13 publications

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“…Следует отметить, что частота встречаемости синдрома сухого глаза или роговично-конъюнктивального ксероза, которая, по разным статистическим данным, отмечается у 23-65% населения, обращающегося на прием к офтальмологам, в последние годы увеличилась. Это связано с широким распространением рефракционной эксимер-лазерной хирургии, ношением контактных линз, ухудшением экологических условий, использованием компьютерной техники и кондиционированием воздуха, применением ботокса для инъекций в параорбитальную область [12][13][14]. В связи с тем что средний возраст беременных составляет от 20 до 38 лет, именно эта возрастная группа в наибольшей степени подвержена негативному влиянию вышеуказанных факторов риска развития ССГ.…”

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The Functional State of Meibomian Glands and Tear Production in Pregnant Women

Трубилин¹,

Полунина²,

Анджелова³

et al. 2018

Ophthalmology in Russia

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Pregnant women are objects of special medical attention due to the fact that the new life — the life of her child — depends on the health and quality of life of the future mother. Pregnancy is a physiological load. It makes temporary changes in the functional state of all organs and systems, including the organ of vision. This study was aimed at identifying risk factors for the occurrence of disturbances in the tear-producing system — dysfunction of the Meibomian glands and/or dry eye syndrome (SSH), as well as to develop recommendations for compensating of disturbance. The study showed that physiological pregnancy does not affect to the condition of the ocular surface in case of absence of dry eye syndrome manifestations and Meibomian gland dysfunction before pregnancy. However, there is a predisposition for the development of the symptom complex of dry eye syndrome — a reliable decrease Schirmer test indicators of the test of in the group of pregnant women, it requires preventive control, — reduction in the mode of wearing contact lenses, which are a risk factor for the development of dry eye syndrome. It was determined that in vitro fertilization (IVF) affects to the condition of the ocular surface, namely, on the occurrence of dysfunction of Meibomian glands and dry eye syndrome, and is accompanied by corresponding complaints. There is a direct correlation between the duration of gestation, age indicators, the severity of complaints and their relationship to pregnancy. A direct was established, with a noticeable tightness of communication, between taking thyrotrophic drugs and complaints on dryness and discomfort. Therefore, special attention should be given to pregnant patients taking thyrotrophic medications and using contact lenses, since both of these factors provoke the development of the dry eye symptom complex. Patients with IVF pregnancy and accompanied by taking thyrotrophic drugs are recommended to limit the mode of wearing contact lenses, in case of complaints on dryness, discomfort, it is necessary to conduct therapeutic and prophylactic effects in the form of non-conserved tear-replacement therapy and eyelid hygiene. Timely diagnosis and subsequent prevention of Meibomian glands and dry eye syndrome in pregnant women will improve the quality of life of this patients group and prevent the development of complications related to this condition.

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The Functional State of Meibomian Glands and Tear Production in Pregnant Women

Трубилин¹,

Полунина²,

Анджелова³

et al. 2018

Ophthalmology in Russia

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The acantamoeba lesions of the cornea (diagnosis) (Review of literature)

Kasparov¹,

Marchenko²,

Kasparova³

2020

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The Aсanthamoeba keratitis is a rare, but very dangerous disease of cornea; its development is connected with contact lens wearing, and corneal microtraumas with contamination of particles of the soil or water. The disease has no pronounced distinguishing clinical signs therefore it is difficult to distinguish them from herpetic or fungal keratitis. Nevertheless, it can be suspected on the basis of anamnestic data (use of contact lenses, corneal injury with contamination by the soil or water), uneven strong pain syndrome, ring-shaped infiltration of cornea, absence of effect of traditional therapy. Isolation of Acanthamoeba by bioculture method, morphological research of corneal bioptat (by light and luminescent microscopy), gene diagnostics, in – vivo confocal microscopy of the cornea can give additional help in the diagnosis. Also perspective diagnostic methods of Acanthamoeba keratitis are given. Nevertheless, so far there is no conventional technique of diagnosis of this disease.

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Clinical Features, Diagnosis, the Results of Therapeutic and Surgical Treatment of Acanthamoebic Keratitis

Cited by 2 publications

References 13 publications

The Functional State of Meibomian Glands and Tear Production in Pregnant Women

The Functional State of Meibomian Glands and Tear Production in Pregnant Women

The acantamoeba lesions of the cornea (diagnosis) (Review of literature)

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