Clinical features, laboratory findings and differential diagnosis of benign acute childhood myositis

Zafeiriou, Dimitrios I.; Katzos, George; Gombakis, N.; Kontopoulos, EE; Tsantali, Chaido

doi:10.1080/080352500456714

Cited by 29 publications

(53 citation statements)

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“…Benign acute childhood myositis is a condition which is characterized by sudden calf pain, inability to walk or difficulty in walking occuring after a prodromal period of 1-5 days following a viral upper respiratory disease and which resolves spontaneously (3). Previous studies reported the prodromal period to range between 2 and 31 days (1)(2)(3)(4)(5)10).…”

Section: Discussionmentioning

confidence: 99%

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Çocukluk çağının selim akut miyoziti: 15 olgunun klinik ve laboratuvar bulguları

Saltık¹,

Sürücü²,

Özdemir³

2012

tpa

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Türk Pe di at ri Ar şi vi Der gi si, Ga le nos Ya yı ne vi ta ra fın dan ba sıl mış tır. / Tur kish Arc hi ves of Pe di at rics, pub lis hed by Ga le nos Pub lis hing Original Article Sum maryAim: In this study, clinical and laboratory findings of 15 cases with benign acute childhood myositis are presented to review pathognomonic findings of the disease. Material and Method: Fifteen typical cases with benign acute childhood myositis referred to our Pediatric Neurology Clinic because of inability to walk from 15th of January to 15th of March 2011 were enrolled into this study. Eighty percent of the cases were male and the mean age was 6.3 years. Guillian-Barre's syndrome was the most common initial diagnosis (47% of the cases). Results:The prodromal period lasted for 2-10 days and common symptoms included sore throat, fever and cough. When they were referred to our clinic, the patients complained of pain in both calves and inability to walk. The symptoms resolved rapidly and spontaneously in 3 days. Leucopenia was found in 87% of the patients, thrombocytopenia was found in 47% of the patients and mildly high alanine transaminase was found in 87% of the patients. Serum creatinine kinase level ranged from 580 to 8250 U/L and returned to normal within one week. Conclusions:In patients whose clinical and laboratory findings are suggestive of benign acute childhood myositis, it is important to consider the diagnosis early in terms of preventing unnecessary laboratory evaluations and different therapeutic approaches. (Turk Arch Ped 2012; 47: 55-8)

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Section: Discussionmentioning

confidence: 99%

“…It occurs in boys more frequently. The typical laboratory finding is high serum creatinine phosphokinase (CPK) level (2,3). Differential diagnosis with Guillain-Barre syndrome (GBS) which leads to difficulty to walk and with more severe diseases which proceed with myoglobinuria is important (3).…”

Section: Introductionmentioning

confidence: 99%

Çocukluk çağının selim akut miyoziti: 15 olgunun klinik ve laboratuvar bulguları

Saltık¹,

Sürücü²,

Özdemir³

2012

tpa

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“…There are several typical skin conditions that can cause similar clinical findings in children, such as dermatomyositis, which presents with a progressive bilateral proximal muscle weakness, an increased CPK level, EMG changes, unusual muscle biopsy findings, edema, and purplish color change in the eyelids [6]. For the diagnosis of BACM, the most typical diagnostic finding is an increased CPK level in the serum [3]. Moderate degree CPK has been reported to range from 558 to 6800.…”

Section: Introductionmentioning

confidence: 99%

“…Usually developings due to post-infectious pathogens, myositis associated with rotaviruses is rarely reported [2]. A typical laboratory finding is a high level of serum keratin phosphokinase (CPK) [3]. Knowing detailed characteristics of benign acute childhood myositis will prevent unnecessary tests and treatments.…”

Section: Introductionmentioning

confidence: 99%

The Benign Childhood Acute Myositis Due to Rotavirus Infections: Case Report

2017

Ann Clin Anal Med

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ÖzÇocukluk çağının akut selim miyoziti özellikle okul çağındaki genellikle erkek ço-cukları etkileyen, alt ekstremitenin distal kaslarını simetrik olarak tutarak yürüme güçlüğüne neden olan ve kendiliğinden düzelen bir klinik durumdur. Akut dönemde, ilerleyerek çocuğun yürümesini engellemesi ve ağrıya yol açmasıyla hekim ve ana babaları telaşlandırabilir. En sık influenza viruslarına bağlı olarak ortaya çıkmak-tadır. Ancak diğer virüsler ile de nadiren görülmektedir. Tipik laboratuvar bulgusu kreatinfosfokinaz düzeyindeki yükselmedir. Ayırıcı tanıda Guillain-Barré sendromu, müsküler distrofiler, dermatomiyozit, piyomiyozit ve büyüme ağrıları vardır.Bu yazıda 5,5 yaşındaki bir kız hastada rotavirüs enfeksiyonuna ikincil olarak gelişen akut myozit tablosu sunulmuştur. Anahtar KelimelerRotavirüs Enfeksiyonları; Çocuk; Myozit; Gastroenterit; Komplikasyonlar AbstractBenign acute childhood myositis usually affects males, especially school children, causes difficulty in walking by keeping the distal muscles of lower extremity symmetrically, and is a clinical condition that resolves spontaneously. In the acute stage, it can alarm the physician and the parents by blocking the child's walking and leading to pain. It arises most frequently due to influenza viruses, while it is rarely seen with other viruses. The typical laboratory finding is an increase in the level of keratin phosphokinase. The differential diagnosis includes Guillain-Barré syndrome, muscular dystrophy, dermatomyositis, pyomyositis, and growing pain. This paper presents an acute myositis case developing secondarily in a rotavirus infection in a 5.5-year-old female patient.

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“…Benign childhood acute myositisis is a muscle syndrome that is most commonly seen after a viral infection [1]. The most common presentation of the disease is acute refusal to walk or altered gait during walking.…”

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confidence: 99%