Clinical Features of Children with COVID-19 Infection: Single-Center Experience

Güler, Muhammet Akif; Laloğlu, Fuat; Orbak, Zerrin; Ceviz, Naci; İşlek, Ali

doi:10.5152/eurasianjmed.2022.21083

Cited by 2 publications

(6 citation statements)

References 28 publications

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“…Although changes in laboratory results have been widely described in adults and in children with COVID-19, there are only a few studies concerning laboratory findings in hospitalized pediatric patients according to age. Similar to our observations, they have all reported leucopenia, neutropenia, lymphocytosis, thrombocytopenia, and elevated CRP, CK, LDH, ALT, and D-dimers as typical in most pediatric patients with COVID-19, especially in patients 0-5 years old [29,40,41,50,51]. Nevertheless, some publications show a relationship between the laboratory parameters at admission and hospitalization and the patient's prognosis at every age.…”

Section: Laboratory Findingssupporting

confidence: 90%

“…Other authors reported much longer stays exceeding 10 days [11,40]. Hospitalization was significantly longer in the group of infants, similar to other authors' reports [11,15,25,40].…”

Section: Disease Outcomesupporting

confidence: 86%

“…The most frequent symptoms were fever, cough, and rhinitis, especially in infants and toddlers. These symptoms were also described by other authors [25,32,[39][40][41][42][43]. In infants, cough and dyspnea were more common symptoms of upper respiratory tract infection, and the most common symptom was laryngitis (Table 5).…”

Section: Clinical Presentation and Final Diagnosessupporting

confidence: 71%

“…Nevertheless, some publications show a relationship between the laboratory parameters at admission and hospitalization and the patient's prognosis at every age. They showed that severe cases had significantly higher levels of mean serum lactate, CRP, ALT, and D-dimers, and an increase in LDH was observed even in asymptomatic patients [40,45,51].…”

Section: Laboratory Findingsmentioning

confidence: 99%

“…These symptoms influenced the need for hospitalization and intravenous rehydration but did not cause a severe and life-threatening course of the disease. In many previous publications, the authors reported gastrointestinal symptoms (vomiting, diarrhea, and abdominal pain) as typical for pediatric patients and more often in younger children [15,25,28,31,39,40,42,44]. Nevertheless, there are some publications reporting a low percentage of gastrointestinal symptoms in hospitalized children [41,45].…”

Section: Clinical Presentation and Final Diagnosesmentioning

confidence: 99%

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The Age-Related Course of COVID-19 in Pediatric Patients—1405 Cases in a Single Center

Stopyra

Kowalik

Stala

et al. 2022

JCM

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Since the beginning of the pandemic, many reports have pointed to age as the most important risk factor for severe COVID-19 in adults, but this relationship is less clear in children. Between March 2020 and April 2022, 1405 pediatric COVID-19 patients were included in our prospective study, which aimed to analyze the disease’s characteristics in three age groups: infants, toddlers (1–5 years), and children (5–18 years). We observed male prevalence of the disease in infants and toddlers compared to female prevalence in children. Comorbidities appeared most often in children. In the first pandemic wave, the vast majority of pediatric patients were children, but later, the percentage of infant and toddler patients increased significantly. A total of 74% of hospitalized children were younger than five years. Upper respiratory tract symptoms were most common in infants and toddlers, and lower respiratory tract symptoms and gastroenterocolitis were more common in children. Neurological symptoms appeared similarly in all age groups. The activities of ALT, CK, and LDH were the most elevated in infants, along with D-dimers. The median length of hospitalization fluctuated between three and four days and was highest in infants. Severe courses were more common in adolescents.

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Section: Laboratory Findingssupporting

confidence: 90%

“…Other authors reported much longer stays exceeding 10 days [11,40]. Hospitalization was significantly longer in the group of infants, similar to other authors' reports [11,15,25,40].…”

Section: Disease Outcomesupporting

confidence: 86%

Section: Clinical Presentation and Final Diagnosessupporting

confidence: 71%

Section: Laboratory Findingsmentioning

confidence: 99%

Section: Clinical Presentation and Final Diagnosesmentioning

confidence: 99%

See 3 more Smart Citations

The Age-Related Course of COVID-19 in Pediatric Patients—1405 Cases in a Single Center

Stopyra

Kowalik

Stala

et al. 2022

JCM

View full text Add to dashboard Cite

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Is Extracorporeal Membrane Oxygenation a Panacea?

Karaoğlanoğlu,

Akgün

2024

The Eurasian Journal of Medicine

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Extracorporeal membrane oxygenation (ECMO) has emerged as a vital life-support technique in critical care medicine, providing temporary circulatory and/or respiratory support for patients with severe cardiac or respiratory failure unresponsive to conventional therapies. This review aims to outline the importance of ECMO and provide a comprehensive overview of its main applications. Two primary types of ECMO, veno-arterial extracorporeal membrane oxygenation and veno-venous extracorporeal membrane oxygenation, serve distinct functions in supporting patients with cardiac or pulmonary dysfunction, respectively. While ECMO offers life-saving potential, its utilization requires careful consideration due to its cost and resource-intensiveness. Thus, a comprehensive evaluation of an individual patient’s clinical condition, prognosis, and potential for recovery is crucial. Ongoing research and technological advancements continually refine ECMO techniques, enhance patient selection criteria, and improve long-term outcomes. Within this narrative review, we present an updated approach to patient selection and ECMO utilization, supported by a detailed literature review. By consolidating the current evidence, we aim to provide healthcare professionals with valuable insights into the ECMO’s post-pandemic role.

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Clinical Features of Children with COVID-19 Infection: Single-Center Experience

Cited by 2 publications

References 28 publications

The Age-Related Course of COVID-19 in Pediatric Patients—1405 Cases in a Single Center

The Age-Related Course of COVID-19 in Pediatric Patients—1405 Cases in a Single Center

Is Extracorporeal Membrane Oxygenation a Panacea?

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