Clinical features of idiopathic guttate hypomelanosis in 646 subjects and association with other aspects of photoaging

Abstract

It is very likely that IGH is a phenomenon associated with the skin's normal aging process and repeated microtrauma to skin.

Dermoscopic evaluation of idiopathic guttate hypomelanosis: A preliminary observation

“…IGH is commonly seen in elderly patients with obscure etiopathogenesis and characterized by hypopigmented or depigmented macules and patches clinically. [3] Authors thought dermoscopy may fill this gap making the possibility of clinical diagnosis of IGH. Dermoscopy, a noninvasive, in vivo technique for the microscopic examination of pigmented skin lesions, has the potential to improve the diagnostic accuracy.…”

Topical tacrolimus significantly promotes repigmentation in idiopathic guttate hypomelanosis: a double‐blind, randomized, placebo‐controlled study

“…demonstrated that photoageing might be associated with IGH. Besides that, 85% of histopathological sections from their patients’ facial IGH lesions revealed mild degree of infiltration by mononuclear inflammatory cells localized in perivascular region of the upper dermis despite of non‐inflammatory clinical appearance of the skin lesions 1 . These findings were indicative of dermatoheliosis.…”

“…In addition, IGH has been considered as a senile skin changes as its prevalence increases with age of patients 1,3 . A recent study from Shin et al.…”

“…The diagnostic criteria used for IGH in this study included acquired lesions, round to oval shape, size less than 2 cm, whitish or porcelain macules, non‐scaly smooth surface, well‐demarcated margin and scattered distribution 1,9 …”

“…Idiopathic guttate hypomelanosis (IGH) is a common condition affecting up to 87% of adults aged more than 40 years 1 . It is characterized by multiple round to oval, hypopigmented or porcelain white macules measuring 0.2–1.6 cm.…”