Clinical features of patients with carcinomatous meningitis in the chinese population: report of 4 cases and review of literature

Duan, Hao; Li, Mei; Sun, Xiaojiang

doi:10.5137/1019-5149.jtn.6936-12.1

Cited by 4 publications

(4 citation statements)

References 8 publications

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“…[ 9 ] In such a patient, naturally, by performing lumbar or thoracic osteotomy, it will be a better choice for the improvement of cervical deformity. [ 20 21 22 ] In patients undergoing decompression and fusion due to cervical stenosis, it is very important to protect cervical parameters; otherwise, HRQOL can also cause serious disruption. [ 23 ]…”

Section: Discussionmentioning

confidence: 99%

Changes in cervical sagittal alignment and the effects on cervical parameters in patients with cervical spondylotic myelopathy after laminoplasty

Özer

Ateş

Cerezci

et al. 2021

Journal of Craniovertebral Junction and Spine

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Objective: To monitor changes in cervical parameters before and after laminoplasty surgery. Cervical parameters and health-related quality-of-life (HRQOL) values that may be affected after laminoplasty were examined before and after surgery. The clinical and radiological course of these values was monitored, and their interaction with all spinal radiological parameters was revealed. Materials and Methods: Nineteen patients who underwent clinical and radiological evaluation for 2 years were followed in this study. Neck disability index, visual analog scale, and short form 36 scores were determined to evaluate HRQOL. For radiological parameters, the C0-C2 angle, C2-C7 angle, cervical sagittal vertical axis, T1 slope angle, neck tilt (NT) and thoracic inlet angle were used. The results of the 4-month, 1 year and 2-year follow-ups were statistically evaluated. Results: Both the HRQOL and cervical radiological parameters deteriorated in the first 4 months and returned to normal in the 2 nd year. Statistically, all parameters were meaningful ( P < 0.05), except for NT. Conclusion: Cervical parameters and HRQOL values, which deteriorated in the early period, recovered in the late period in the long-term follow-up of patients undergoing laminoplasty. The important point is that preoperative cervical parameters suitable for laminoplasty should be present, and spinopelvic parameters should be normal.

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Section: Discussionmentioning

confidence: 99%

Changes in cervical sagittal alignment and the effects on cervical parameters in patients with cervical spondylotic myelopathy after laminoplasty

Özer

Ateş

Cerezci

et al. 2021

Journal of Craniovertebral Junction and Spine

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“…The two patients in this study all presented progressive headache from the early stage to the end and the opening pressure of the first patient increasing from 200 to 350 mmH 2 O was consistent with her headache. The headache progresses quickly and is usually insufferable in the last stage until to cerebral herniation [5]. In view of the feature, the diagnosis of MC could keep in mind and further examination such as CSF cytology and brain MRI should be arranged to identify the disease.…”

Section: Discussionmentioning

confidence: 99%

Gadobutrol-enhanced magnetic resonance imaging of meningeal carcinomatosis: case report with emphasis on early diagnosis

Pan

Wen

et al. 2016

BMC Neurol

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BackgroundTimely diagnosis of meningeal carcinomatosis is often difficult even with the assistant of magnetic resonance imaging examination, cerebrospinal fluid analysis, or both. To the best of our knowledge, gadobutrol-enhanced MRI has not been reported in the diagnosis of meningeal carcinomatosis. Here we present two cases where meningeal carcinomatosis was identified on gadobutrol-enhanced magnetic resonance imaging.Case presentationWe identified two cases of meningeal carcinomatosis who had been diagnosed with malignant tumors several years ago. Both patients presented with progressive headache and seizures. Gadopentetate dimeglumine-enhanced magnetic resonance imaging of the brain was performed and did not detect any abnormality of meninges. Lumbar puncture was performed repeatedly, but cerebrospinal fluid cytology showed no evidence of malignant cells. Finally the gadobutrol-enhanced magnetic resonance imaging detected the meningeal metastasis, and supported the diagnosis of meningeal carcinomatosis.ConclusionGadobutrol provides higher lesion conspicuity and enhances lesion detection in meningeal metastasis compared with gadopentetate dimeglumine. Our observation is a cue to analyze the accuracy in the diagnosis of meningeal carcinomatosis, and presents a choice that may facilitate early diagnosis.

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“…The tumor cells disseminated to the leptomeninges occur via direct invasion, hematogenous spread, or perineural spread especially in head and neck cancer [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

Cauda Equina Syndrome Secondary to Leptomeningeal Carcinomatosis of Gastroesophageal Junction Cancer

Alkhotani¹,

Alrishi

Alhalabi

et al. 2016

Case Rep Neurol

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Leptomeningeal carcinomatosis (LMC) is a diffuse or multifocal malignant infiltration of the pia matter and arachnoid membrane. The most commonly reported cancers associated with LMC are breast, lung, and hematological malignancies. Patients with LMC commonly present with multifocal neurological symptoms. We report a case of LMC secondary to gastroesophageal junction cancer present initially with cauda equina syndrome. A 51-year-old male patient with treated adenocarcinoma of the gastroesophageal junction presented with left leg pain, mild weakness, and saddle area numbness. Initial radiological examinations were unremarkable. Subsequently, he had worsening of his leg weakness, fecal incontinence, and urine retention. Two days later, he developed rapidly progressive cranial neuropathies including facial diplegia, sensorineural hearing loss, dysarthria, and dysphagia. MRI with and without contrast showed diffuse enhancement of leptomeninges surrounding the brain, spinal cord, and cauda equina extending to the nerve roots. Cerebrospinal fluid cytology was positive for malignant cells. The patient died within 10 days from the second presentation. In cancer patients with cauda equina syndrome and absence of structural lesion on imaging, LMC should be considered. To our knowledge, this is the first case of LMC secondary to gastroesophageal cancer presenting with cauda equina syndrome.

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Clinical features of patients with carcinomatous meningitis in the chinese population: report of 4 cases and review of literature

Cited by 4 publications

References 8 publications

Changes in cervical sagittal alignment and the effects on cervical parameters in patients with cervical spondylotic myelopathy after laminoplasty

Changes in cervical sagittal alignment and the effects on cervical parameters in patients with cervical spondylotic myelopathy after laminoplasty

Gadobutrol-enhanced magnetic resonance imaging of meningeal carcinomatosis: case report with emphasis on early diagnosis

Cauda Equina Syndrome Secondary to Leptomeningeal Carcinomatosis of Gastroesophageal Junction Cancer

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