Clinical features of pregnant women in Iran who died due to COVID‐19

Moghadam, Soheila Amini; Dini, Parisa; Nassiri, Setare; Motavaselian, Mahtab; Hajibaba, Marzieh; Sohrabi, Masoudreza

doi:10.1002/ijgo.13461

Cited by 6 publications

(6 citation statements)

References 25 publications

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“…We found neutrophilia but no lymphocytopenia in severe cases of pregnant women. Our findings of increased white-blood-cell count and neutrophil count are supported by the findings of Moghadam [ 37 ] in severe cases of pregnant SARS-CoV-2-infected women.…”

Section: Discussionsupporting

confidence: 91%

Brixia and qSOFA Scores, Coagulation Factors and Blood Values in Spring versus Autumn 2021 Infection in Pregnant Critical COVID-19 Patients: A Preliminary Study

et al. 2022

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(1) Background: From the recent variants of concern of the SARS-CoV-2 virus, in which the delta variant generated more negative outcomes than the alpha, we hypothesized that lung involvement, clinical condition deterioration and blood alterations were also more severe in autumn infection, when the delta variant dominated (compared with spring infections, when the alpha variant dominated), in severely infected pregnant patients. (2) Methods: In a prospective study, all pregnant patients admitted to the ICU of the Elena Doamna Obstetrics and Gynecology Hospital with a critical form of COVID-19 infection—spring group (n = 11) and autumn group (n = 7)—between 1 January 2021 and 1 December 2021 were included. Brixia scores were calculated for every patient: A score, upon admittance; H score, the highest score throughout hospitalization; and E score, at the end of hospitalization. For each day of Brixia A, H or E score, the qSOFA (quick sepsis-related organ failure assessment) score was calculated, and the blood values were also considered. (3) Results: Brixia E score, C-reactive protein, GGT and LDH were much higher, while neutrophil count was much lower in autumn compared with spring critical-form pregnant patients. (4) Conclusions: the autumn infection generated more dramatic alterations than the spring infection in pregnant patients with critical forms of COVID-19. Larger studies with more numerous participants are required to confirm these results.

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Section: Discussionsupporting

confidence: 91%

Brixia and qSOFA Scores, Coagulation Factors and Blood Values in Spring versus Autumn 2021 Infection in Pregnant Critical COVID-19 Patients: A Preliminary Study

et al. 2022

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“…Apenas quatro estudos analisados descreveram a faixa etária dos casos de mortalidade materna por COVID-19 (HANTOUSHZADEH et al, 2020;BELOKRINITSKAYA et al, 2021;ASALKAR et al, 2021;MOGHADAM et al, 2021). Houve variação das faixas etárias, um estudo destacou a faixa entre 25 e 35 anos, a qual é reconhecida como a idade reprodutiva feminina (ASALKAR et al, 2021), outros dois estudos descreveram a mesma tendência, com a média de idade com variação entre 30 a 32,3 anos (MOGHADAM et al, 2020;BELOKRINITSKAYA et al,2021).…”

Section: B) Caracterização Da Mortalidade Maternaunclassified

Perfil epidemiológico da mortalidade materna por COVID-19: revisão integrativa

Cunha¹,

Cardoso

Matricardi

et al. 2022

CONJ

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A taxa de mortalidade materna relacionada à COVID-19 foram variáveis e aumentaram na maioria dos países. Portanto, o objetivo deste estudo foi sumarizar as evidências científicas referentes aos casos de mortalidade materna por COVID-19 ao nível global. Trata-se de uma pesquisa de revisão integrativa com busca nas bases: EMBASE, SCOPUS (Elsevier), PUBMED, Web of Science, CINAHL, no período de fevereiro a março de 2022. Os artigos foram pré-triados através do software Rayyan QCRI, os selecionados foram lidos na íntegra e os dados coletados conforme o Critical Appraisal of the Evidence, a hierarquia das evidências pelo Hierarchy of Evidence for Intervention Studies. Foram selecionados 15 publicações, que ocorreram entre os anos de 2020 a 2022, sendo a maior proporção no ano de 2021. Os países de origem dos estudos foram Índia, Estados Unidos, México, Irã, Brasil, Rússia, e um estudo multicêntrico em 16 países. Dois artigos evidenciaram as semanas epidemiológicas e os picos de óbito materno no ano de 2020. Estudos evidenciaram o aumento da Razão de Mortalidade Materna entre os anos de 2020 e 2021 apesar da tendência de queda. Risco e taxa de letalidade foram identificados com elevação. Foi possível identificar o perfil clínico das gestantes que foram a óbito, dentre os quais a faixa etária acima de 35 anos e grupos com comorbidades pré-existentes, apenas um estudo relacionou a deficiência de ferro com agravamento clínico. É possível sugerir com esta revisão que as mulheres gestantes, tendem a ser mais vulneráveis e propensas a agravamentos clínicos por COVID-19.

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“…Gastrointestinal symptoms such as nausea (n = 14, 1%), vomiting (n = 14, 1%) and diarrhea (n = 7, 0.5%) were also present in some patients. All symptoms and clinical and laboratory data have been summarized in Table 2 and Table S1 (see Supplementary file 1 8,[12][13][14][15][16][17][18][19][20][21][22] ).…”

Section: Maternal Clinical Characteristics and Outcomesmentioning

confidence: 99%

“…Common complications and prescribed medications have been summarized in Tables S2 and S3, respectively (see Supplementary file 1). 8,[12][13][14][15][16][17][18][19][20][21][22] Neonatal Complications Eight studies including seven case reports and one case series were selected that determined the neonatal complication of SARS-CoV-2 in newborns born to infected mothers. The characteristics of these selected studies have been summarized in Table 4.…”

Section: Maternal Clinical Characteristics and Outcomesmentioning

confidence: 99%

Maternal and Neonatal Complications, Outcomes and Possibility of Vertical Transmission in Iranian Women with COVID-19

et al. 2021

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Background: The emergence and fast spread of coronavirus disease 2019 (COVID-19) threatens the world as a new public health crisis. Little is known about its effects during pregnancy. This study aimed to investigate the clinical manifestations of COVID-19 on maternal and neonatal outcomes. Methods: In this systematic review, PubMed, Scopus, Web of Science, and Google Scholar databases were searched focusing on pregnancy and perinatal outcomes of COVID-19. Results: The initial search yielded 1236 articles, from which finally 21 unique studies, involving 151 pregnant women and 17 neonates, met the criteria. Mean ± SD age of included mothers and mean ± SD gestational age at admission were 30.6 ± 6.2 years and 30.8 ± 8.9 weeks, respectively. The common symptoms were fever, cough, fatigue, dyspnea and myalgia. The mortality rates of pregnant women and neonates were 28 out of 151 (18.5%) and 4 out of 17 (23.5%), respectively. Most of the neonates were preterm at the time of delivery. Three neonates had positive RT-PCR test on the first day after birth and three others on day two. On the average, neonate’s PCR became positive on day 4 for the first time. Conclusion: Early diagnosis of COVID-19 is crucial due to the possibility of the prenatal complications. Strict prevention strategies may reduce the risk of mother to infant transmission.

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Clinical features of pregnant women in Iran who died due to COVID‐19

Abstract: Background: To evaluate the clinical presentation of pregnant women in Iran who died due to COVID-19.

Cited by 6 publications

References 25 publications

Brixia and qSOFA Scores, Coagulation Factors and Blood Values in Spring versus Autumn 2021 Infection in Pregnant Critical COVID-19 Patients: A Preliminary Study

Brixia and qSOFA Scores, Coagulation Factors and Blood Values in Spring versus Autumn 2021 Infection in Pregnant Critical COVID-19 Patients: A Preliminary Study

Perfil epidemiológico da mortalidade materna por COVID-19: revisão integrativa

Maternal and Neonatal Complications, Outcomes and Possibility of Vertical Transmission in Iranian Women with COVID-19

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