Clinical Findings Leading to the Diagnosis of Sepsis in Neonates Hospitalized in Imam Khomeini and Bu Ali Hospitals, Sari, Iran: 2011-2012

Abstract

Background:One of the important diseases in neonatal period is sepsis. Clinical sign and symptoms in addition to lab tests are the most important way to accurate diagnosis and prevention of mortality. This study was conducted with the aim of determining the most clinical sign and symptoms which leading to diagnosis of sepsis.Materials and Methods:This is a descriptive cross-sectional study. The medical records of patients hospitalized in hospitals of Mazandaran University of Medical Sciences during 2011-2012 were reviewed. Variables were age, sex, birth and admission weight, clinical sign and symptoms, methods of delivery, admission and discharge condition, discharge status, the time elapsed between showing the symptom and admission to hospital, gestational age and the result of cultures. The data were recorded in a checklist and analyzed with SPSS and descriptive statistics.Results:finding showed that 120 patients discharged during period of study with diagnosis of sepsis. Discharged status of 27 (%22/5) were expired. Median age was 1 day with 8 hours SD, length of stay were 12±1 days, gestational age was 34±3 weeks and median birth weight was 2477±977 grams. The median time elapsed between showing the symptom and admission to hospital was 38±31 hours. Blood culture in 10 (%8/3) and urine culture in 8 (%7/6) patients were positive. None of patients have positive lumbar puncture culture. The frequent sign and symptpms in patients were respiratory distress, poor feeding and lethargy.Conclusion:Early diagnosis of neonatal sepsis is not possible only by specific laboratory exams. Clinical sign and symptoms can help us to prediction and diagnosis of neonatal sepsis. Results of this research revealed that it is not clear which one of manifestations was started first or the second because of medical history sheets don’t show this process.

Role of Maternal Risk Factors and Neonatal Clinical Features in Diagnosis of Neonatal Sepsis: A Case Control Study

“…29 Respiratory distress was a symptom of neonatal sepsis in 47% neonates while previous reports suggest ~28% respiratory distress among neonatal sepsis. 29 Lethargy was seen in 60% cases in contrast to reports of lethargy in 15% neonates with sepsis. Jaundice was reported in 38% though previous reports suggest it in 7.4% neonates with sepsis.…”

“…63.3% neonates with sepsis had poor feeding and is reported as a symptom prevalent in initial four days of neonatal period more commonly during the 3 rd and 4 th day of neonatal life. 29 Vomiting was observed among 23% neonates and has been described as a feature of late onset neonatal sepsis. 29 Respiratory distress was a symptom of neonatal sepsis in 47% neonates while previous reports suggest ~28% respiratory distress among neonatal sepsis.…”

“…29 Vomiting was observed among 23% neonates and has been described as a feature of late onset neonatal sepsis. 29 Respiratory distress was a symptom of neonatal sepsis in 47% neonates while previous reports suggest ~28% respiratory distress among neonatal sepsis. 29 Lethargy was seen in 60% cases in contrast to reports of lethargy in 15% neonates with sepsis.…”

Cost and Time Reduction of Industrial Mold Design and Manufacturing by Implementing Additive Manufacturing for Premature Neonatal Prong

“…Babies born under 37 weeks gestational age are called premature [14]. Today, the highest number of neonatal intensive care unit admissions are preterm babies [15].…”

<p>Relationship of glucose-6-phosphate dehydrogenase deficiency and neonatal sepsis: a single-center investigation on the major cause of neonatal morbidity and mortality</p>

“…Neonatal sepsis is a serious disease with defined clinical and laboratory findings, which is confirmed through positive blood culture. If is not diagnosed rapidly and treated completely, it can lead to permanent disability, multiple organ failure, shock or death 1,2…”