About 50% of the general population has a chronic disease not cured by biomedicine. Objectives: Meta-analysis of holistic clinical medicine for which chronic patients were treated and outcomes were, 1) global quality of life, 2) self-rated physical/ mental health, quality of life or ability of functioning, or 3) patients felt cured for a specific disease of dysfunction. Method'. MEDLINE and PsycINFO and specific journals were searched in January 2009. Results: Eleven clinical studies (18,500 participants) were identified. Positive effects: Quality of life Number Needed to Treat (NNT) = 2, physical health problems NNT = 3, mental health problems NNT = 2, sexual dysfunctions NNT = 2, self esteem NNT = 2, working/studying ability NNT = 2, anorgasmia NNT = 1, other specific sexual dysfunctions NNT = 2. Of 791 patients treated was 617, or 78.0% cured (NNT = 1). Side effects and adverse events: re-traumatization Number Needed to Harm (NNH) > 18,500; brief reactive psychosis (if mentally ill) NNH = 4,625; brief reactive psychosis (if not mentally ill) NNH > 9,250; brief reactive psychosis, all patients NNH = 9,250; depression NNH > 18,500; depersonalization and derealization NNH > 18,500; iatrogenic disturbances NNH > 18,500; minor bone fractures (ribs, hand) NNH = 4,625; serious bone fractures (spine, scull, pelvis) NNH > 18,500: suicides during or less than three month after therapy NNH > 18,500; suicide attempts during or less than three month after therapy NNH > 18,500. Suicide was prevented NNT = 1. Therapeutic value TV = NNH/NNT = 9,250. Conclusions: Holistic clinical medicine is an efficient complementary and alternative medicine (CAM) treatment for chronic illnesses and health related problems. Every second patient with physical and mental disorders, sexual dysfunctions, and existential problems were healed. Holistic clinical medicine had no significant side effects or adverse events. Brought to you by | University of Arizona Authenticated Download Date | 6/3/15 6:01 AM Physical diseases Asthma, eczema, allergy (59,90) Chronic infections and autoimmune diseases (63,90) Chronic pain (musculoskeletal and inner organs) (55,56,90) Cancer (3,57,61,90,99,100)-improving quality of life, reducing pain, and increasing survival Coronary heart disease (1,2,90) HIV -improving quality of life and possibly also survival (56) Neurologic dysfunction (Brain Damage, Narcolepsy, Dementia, Intelligence Deficit) (90,101-105) Rheumatologie disease (63,90,106)
Mental disordersEating disorders (60,68,86,91) Low self-esteem and self confidence (60,94) Anxiety (35,36,91) Schizophrenia and schizotypia (69,70,83,85,91) Borderline and other disorders of personality (35,36,69,70,85,91) Depression and hypothymia (mood and emotional disorders) (69,70,91) Alcoholism, ludomania, other types of dependency (62,91) Children and adolescence with autism or behavioural disturbances including ADHD (53,60,93) Post traumatic stress and other sequelae of violent or sexual trauma like rape and incest (24,25,40,55,60,64,66,76,77,91,98) Sexual and gynaecolog...